Abstract: This invention relates to a fixed-dose dry powder inhalation formulation comprising fluticasone propionate and albuterol sulfate, together with an ?-lactose monohydrate carrier. In the formulation, the albuterol sulfate stabilises fluticasone propionate.

Abstract: A text mining system providing NLP and NLU capabilities is operable to perform, at a first processing layer, a first operation on input data to produce metadata about the input data. At a second processing layer, a rules module applies a composite AI extraction rule to further process the input data. The composite AI extraction rule has a rule condition that leverages the metadata from the first operation and a rule action that involves a second operation. Other composite AI extraction rules involving multiple text mining operations may also be applied. For instance, a rule may specify using the tonality of a document from a sentiment analysis to classify the document according to a relevant taxonomy. Another rule may specify classifying documents of a particular type under a specific category. In this way, new/enhanced information about the input data can be deduced, validated, and/or enriched.

Abstract: This disclosure relates generally to improved methods of preparing pyrazolylthiazole-containing compounds and their intermediates.

Abstract: A system for aiding translation from a first language to a second language includes a frontend and a backend. An input document can be subdivided into segments, which in turn can be fragmented into document fragments. A document fragment, selected by a translator, can be further edited by that translator into sub-fragments which in turn can be provided as input to one or more suggestion engines. Output from the suggestion engines includes prior human translations of the sub-fragment, machine translations of the sub-fragment, and/or hybrid combinations thereof.

Abstract: An aircraft system has a first structure, and a second structure coupled to the first structure and movable between first and second positions relative to the first structure. The aircraft system has an electrical connector for providing an electrical connection running between respective components housed within the first and second structures. The electrical connector has a cable harness housed within the first structure, and a connector body coupled to an end of the cable harness. The connector body extends through an aperture formed in the first structure, and the connector body is coupled to the second structure such that movement of the second structure between the first and second positions relative to the first structure causes the connector body to move through the aperture.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: This disclosure provides a method for treating a subject afflicted with a tumor or a cancer, wherein the method comprises administering to the subject therapeutically effective amounts of an anti-TIM3 antibody, alone or in combination with an inhibitor of the PD-1 signaling pathway (e.g., anti-PD-1 antibody). In some embodiments, the antibody is administered as a flat dose or a weight-based dose.

Abstract: A disposable glove apparatus. A cartridge of disposable gloves can be configured and mounted for presentation to a user. A user's hands in proximity to an open portion of a glove causes a gas flow to inflate a pair of gloves. A user can insert hands into the open gloves and remove them, thereby donning gloves in an easy and sanitary manner.

Abstract: A text mining system providing NLP and NLU capabilities is operable to perform, at a first processing layer, a first operation on input data to produce metadata about the input data. At a second processing layer, a rules module applies a composite AI extraction rule to further process the input data. The composite AI extraction rule has a rule condition that leverages the metadata from the first operation and a rule action that involves a second operation. Other composite AI extraction rules involving multiple text mining operations may also be applied. For instance, a rule may specify using the tonality of a document from a sentiment analysis to classify the document according to a relevant taxonomy. Another rule may specify classifying documents of a particular type under a specific category. In this way, new/enhanced information about the input data can be deduced, validated, and/or enriched.

Abstract: This invention relates to a fixed-dose dry powder inhalation formulation comprising fluticasone propionate and albuterol sulfate, together with an ?-lactose monohydrate carrier. In the formulation, the albuterol sulfate stabilises fluticasone propionate.

Abstract: Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.

Abstract: There is provided a system, method, and computing device for distribution of cryptographic key generation data in a secure network, the secure network comprising a security server and one or more clients. The method including: receiving or generating indexed random data; communicating at least a portion of the indexed random data to one of the clients; and receiving or communicating the indices of the portions of the indexed random data shared with the client, a portion of the indexed random data is used for cryptographic key generation for encrypted communication between the client and another client. In some cases, the above is repeated for each client, wherein the indexed random data is unique for each client.

Abstract: An antibody has a glutamine-containing extension at the C-terminus of a light chain thereof, making it suitable for conjugation via transglutaminase-mediated transamidation.

Abstract: A multi-zone media system and method for providing multi-zone media. As a non-limiting example, various aspects of this disclosure provide a system and method that flexibly presents media content (e.g., audio content) to a user as the user moves throughout a premises.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof.

Abstract: A disposable glove apparatus. A cartridge of disposable gloves can be configured and mounted for presentation to a user. A user's hands in proximity to an open portion of a glove causes a gas flow to inflate a pair of gloves. A user can insert hands into the open gloves and remove them, thereby donning gloves in an easy and sanitary manner.

Abstract: The invention relates to a process to convert a carbon containing material contained in a waste feed, such as synthetic polymer and/or hydrocarbon, providing effective carbonization to produce carbon and optionally also hydrogen, said process comprising contacting and mixing the carbon containing material with a hydratable molten salt and converting in a carbonisation reactor into a conversion gas and a reaction mixture comprising non-volatile conversion products being solid carbon, collecting conversion gas and adding water or steam to the reaction mixture to re-hydrate the molten salt whereby phase separation occurs forming a non-volatile carbon containing phase and a re-hydrated molten salt phase, separating and de-hydrating the molten salt phase and recycling the dehydrated molten salt and steam back in the process.

Abstract: Provided are systems and methods for importing application content from a cloud environment where the application is being hosted onto a local user device. In one example, the method may include receiving, at a user device, a package exported from a host platform, extracting content of a software application hosted on the host platform and a script from the exported package, invoking the script within a runtime environment on the user device, and causing, via the script, a transfer objects of cloud content of the software application which are included in the exported package to a file system that is installed in a local storage on the user device.

Abstract: A method of improving patient recovery after a surgery includes: providing a pre-operative protocol, the pre-operative protocol having a first set of instructions for the consumption of a first nutritional supplement; and providing a post-operative protocol, the post-operative protocol having a second set of instructions for the consumption of a second nutritional supplement. The first set of instructions has an instruction to consume or administer the pre-operative protocol for seven days prior to the surgery. The first nutritional supplement has a base, vitamin D, Calcium, magnesium, potassium, sodium, ashwagandha, glutamine, and arginine in quantities selected to improve recovery after surgery. The second set of instructions has an instruction to consume or administer the post-operative protocol for thirty days after surgery.