Abstract: An antibody has a glutamine-containing extension at the C-terminus of a light chain thereof, making it suitable for conjugation via transglutaminase-mediated transamidation.

Abstract: A multi-zone media system and method for providing multi-zone media. As a non-limiting example, various aspects of this disclosure provide a system and method that flexibly presents media content (e.g., audio content) to a user as the user moves throughout a premises.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: Provided herein are antibodies, or antigen binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen binding portions thereof.

Abstract: A disposable glove apparatus. A cartridge of disposable gloves can be configured and mounted for presentation to a user. A user's hands in proximity to an open portion of a glove causes a gas flow to inflate a pair of gloves. A user can insert hands into the open gloves and remove them, thereby donning gloves in an easy and sanitary manner.

Abstract: The invention relates to a process to convert a carbon containing material contained in a waste feed, such as synthetic polymer and/or hydrocarbon, providing effective carbonization to produce carbon and optionally also hydrogen, said process comprising contacting and mixing the carbon containing material with a hydratable molten salt and converting in a carbonisation reactor into a conversion gas and a reaction mixture comprising non-volatile conversion products being solid carbon, collecting conversion gas and adding water or steam to the reaction mixture to re-hydrate the molten salt whereby phase separation occurs forming a non-volatile carbon containing phase and a re-hydrated molten salt phase, separating and de-hydrating the molten salt phase and recycling the dehydrated molten salt and steam back in the process.

Abstract: Provided are systems and methods for importing application content from a cloud environment where the application is being hosted onto a local user device. In one example, the method may include receiving, at a user device, a package exported from a host platform, extracting content of a software application hosted on the host platform and a script from the exported package, invoking the script within a runtime environment on the user device, and causing, via the script, a transfer objects of cloud content of the software application which are included in the exported package to a file system that is installed in a local storage on the user device.

Abstract: A method of improving patient recovery after a surgery includes: providing a pre-operative protocol, the pre-operative protocol having a first set of instructions for the consumption of a first nutritional supplement; and providing a post-operative protocol, the post-operative protocol having a second set of instructions for the consumption of a second nutritional supplement. The first set of instructions has an instruction to consume or administer the pre-operative protocol for seven days prior to the surgery. The first nutritional supplement has a base, vitamin D, Calcium, magnesium, potassium, sodium, ashwagandha, glutamine, and arginine in quantities selected to improve recovery after surgery. The second set of instructions has an instruction to consume or administer the post-operative protocol for thirty days after surgery.

Abstract: The present invention generally relates to golf shoes having a lace tightening system. The shoe includes an upper, midsole, and outsole. The upper includes various lace guides that are separated by gaps. The lace is threaded through these guides and the lace can be tightened or loosened. The lace tightening system can be used to close the instep region around the foot to secure the shoe and provide a comfortable fit. The midsole provides cushioning to the shoe. The outsole preferably contains multiple traction members to provide good stability and ground contact. The shoes of this invention help provide the golfer with stability and balance.

Abstract: A multi-zone media system and method for providing multi-zone media. As a non-limiting example, various aspects of this disclosure provide a system and method that flexibly presents media content (e.g., audio content) to a user as the user moves throughout a premises.

Abstract: A system and method for providing zone-specific media to a user. As a non-limiting example, various aspects of this disclosure provide a system and method that flexibly selects and provides media content (e.g., audio content), where such content is selected based, at least in part, on a user location (e.g., location within a premises).

Abstract: A text mining system providing NLP and NLU capabilities is operable to perform, at a first processing layer, a first operation on input data to produce metadata about the input data. At a second processing layer, a rules module applies a composite AI extraction rule to further process the input data. The composite AI extraction rule has a rule condition that leverages the metadata from the first operation and a rule action that involves a second operation. Other composite AI extraction rules involving multiple text mining operations may also be applied. For instance, a rule may specify using the tonality of a document from a sentiment analysis to classify the document according to a relevant taxonomy. Another rule may specify classifying documents of a particular type under a specific category. In this way, new/enhanced information about the input data can be deduced, validated, and/or enriched.

Abstract: A disposable glove apparatus. A cartridge of disposable gloves can be configured and mounted for presentation to a user. A user's hands in proximity to an open portion of a glove causes a gas flow to inflate a pair of gloves. A user can insert hands into the open gloves and remove them, thereby donning gloves in an easy and sanitary manner.

Abstract: Using approximated bin intervals to label the histograms provides clarity and allows for the histogram to be more intuitively understood. A dataset may comprise a plurality of records having a plurality of features including one or more continuous features. A selection of a continuous feature may be obtained. A bin width based on a number of bins and feature statistics of the continuous feature may be determined. An approximated bin interval range is determined by applying a bin mask based on the bin width to the feature statistics. An approximated bin width is determined based on the number of bins and the approximated bin interval range. Approximated bin intervals for the histogram are determined based on the approximated bin width. A histogram is generated having bins with intervals based the approximated bin intervals.

Abstract: Embodiments describe a technique for database schema migration that minimizes queries to the runtime database. A technique is described for detecting whether design time metadata has changed during a schema migration without performing a database query for runtime metadata and comparing the design time metadata with the runtime metadata. The technique may improve performance since it aims at minimizing the number of times the database is queried for runtime metadata during the schema migration.

Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: Anomalies may be detected using a multiple machine learning model anomaly detection framework. A clustering model is trained using an unsupervised machine learning algorithm on a historical anomaly dataset. A plurality of clusters of records are determined by applying the historical anomaly dataset to the clustering model. Then it is determined whether each cluster of the plurality of clusters is an anomaly-type cluster or a normal-type cluster. The plurality of labels for the plurality of records are updated based on the particular record's cluster classification. Non-pure clusters are determined from among the plurality of clusters based on a purity threshold. A supervised machine learning model is trained for each of the non-pure clusters using the records in the given cluster and the labels for each of those records. Then, predictions of an anomaly are made using the clustering model and the supervised machine learning models.

Abstract: Embodiments provide systems, methods and computer program products for cloud replication of data. One embodiment includes, accessing a virtual table definition and a data collection definition, the virtual table definition comprising a definition of a set of virtual table fields and a mapping of the set of virtual table fields to a set of target data types; automatically creating a virtual table according to the virtual table definition, the virtual table comprising the set of virtual table fields populated with the data of interest according to the data collection definition; and sending the virtual table and the mapping to a cloud computing environment. One embodiment further includes, in the cloud computing environment, storing the set of virtual table fields as a set of physical table fields in a physical table in a cloud hosted database, the set of physical table fields having the set of target data types.

Abstract: Embodiments of the present disclosure provide techniques for associating use case data with data listings in a structured manner. A processing device provides a listing creation interface that is used to assign a set of use cases to a first data listing and publish the data listing on a data exchange. The data listing is one of a plurality of data listings published on the data exchange and the processing device provides a data listing interface for displaying the plurality of data listings and an interactable menu including a selectable indication of each of the plurality of use cases. In response to receiving a selection of one or more of the plurality of use cases via the interactable menu, the processing device displays in the data listing interface, each of the plurality of data listings that have been assigned any of the selected one or more use cases.

Abstract: A composition comprising a synthetic growth factor analogue comprising a non-growth factor heparin binding region, a linker and a sequence that binds specifically to a cell surface receptor and an osteoconductive material where the synthetic growth factor analogue is attached to and can be released from the osteoconductive material and is an amplifier/co-activator of osteoinduction.