Patents by Inventor Paul Offit

Paul Offit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aqueous solven encapsulation method, apparatus and microcapsules
    Patent number: 6531156
    Abstract: The present invention relates to microcapsules comprising a wall and an aqueous core comprising various active agents, and prepared by the interfacial reaction in aqueous medium of Lewis acid and base wall-forming reactants.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: March 11, 2003
    Assignees: Temple University, Children's Hospital of Philadelphia
    Inventors: Fred M. Clark, Paul A. Offit, Tully J. Speaker
  • Rotavirus reassortant vaccine
    Patent number: 6290968
    Abstract: The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: September 18, 2001
    Assignees: Children's Hospital of Philadelphia, Wistar Institute of Anatomy and Biology
    Inventors: H Fred Clark, Paul Offit, Stanley A. Plotkin
  • Aqueous solvent based encapsulation of a bovine herpes virus type-1 subunit vaccine
    Patent number: 6270800
    Abstract: A microencapsulated subunit component from bovine herpes virus-1 (BHV-1) is disclosed. Vaccines, kits, and methods for using the same to vaccinate a member of a bovine species are also disclosed.
    Type: Grant
    Filed: April 21, 1998
    Date of Patent: August 7, 2001
    Assignee: Pfizer Inc.
    Inventors: Tully J. Speaker, H. Fred Clark, Charlotte A. Moser, Paul A. Offit, Manuel Campos, Patrick J. Frenchick
  • Rotavirus reassortant vaccine
    Patent number: 6113910
    Abstract: The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
    Type: Grant
    Filed: May 11, 1998
    Date of Patent: September 5, 2000
    Assignees: The Children's Hospital of Philadelphia, The Winstar Institute of Anatomy and Biology
    Inventors: H Fred Clark, Paul Offit, Stanley A. Plotkin
  • Rotavirus reassortant vaccine
    Patent number: 5750109
    Abstract: The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: May 12, 1998
    Assignees: The Wistar Institute of Anatomy & Biology, The Children's Hospital of Philadelphia
    Inventors: H. Fred Clark, Paul Offit, Stanley A. Plotkin
  • Rotavirus reassortant vaccine
    Patent number: 5626851
    Abstract: The present invention provides novel rotavirus reassortants, vaccines employing the novel reassortants and methods for their preparation and administration. One such reassortant contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus. Another reassortant contains the gene encoding the v.p.4 neutralization antigen of a human rotavirus. The remaining genes are provided solely from the bovine rotavirus WC3 strain, or from both the human and bovine strains.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: May 6, 1997
    Assignees: The Wistar Institute of Anatomy and Biology, The Children's Hospital of Philadelphia
    Inventors: H. Fred Clark, Paul Offit, Stanley A. Plotkin