Patents by Inventor Paul On-Pong Ts'o

Paul On-Pong Ts'o has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs, triple helix complexes formed thereby and oligomers used in their formation

Patent number: 5834185

Abstract: Methods of detecting, recognizing or inhibiting or altering expression of a target sequence of a single stranded nucleic acid having any combination of purine and pyrimidine nucleosides by formation of triple helix complexes in conjunction with Second and Third Strands which comprise optionally covalently linked Oligomers are provided.

Type: Grant

Filed: November 21, 1994

Date of Patent: November 10, 1998

Assignee: Johns Hopkins University

Inventors: Paul On-Pong Ts'o, Tina Lynn Trapane

Formation of triple helix complexes of single stranded nucleic acids using nucleoside oligomers which comprise pyrimidine analogs, triple helix complexes formed thereby and oligomers used in their formation