Patents by Inventor Paul Oran

Paul Oran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180374584
    Abstract: The disclosure herein relates generally to the dynamic presentation of health information and treatment options. Methods and systems for automatically causing the display of a desired visual depiction of health information and treatment options are disclosed.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 27, 2018
    Inventor: Paul Oran
  • Publication number: 20160042152
    Abstract: The disclosure herein relates generally relate, for example, to the dynamic identification of health goals (such as health therapies, plans, and guidance, among other examples) and related devices and/or computing applications. Methods and systems for automatically determining and causing the display of such health goals, devices and computing applications are disclosed.
    Type: Application
    Filed: September 8, 2014
    Publication date: February 11, 2016
    Inventor: Paul Oran
  • Publication number: 20130217630
    Abstract: The invention relates to PTH variants and uses thereof in the detection, diagnosis, and treatment of various disease states.
    Type: Application
    Filed: October 26, 2011
    Publication date: August 22, 2013
    Applicant: ARIZONA BOARD OF REGENTS, a body corporate of the State of Arizona, acting for an on behalf of Arizo
    Inventors: Randall W. Nelson, Paul Oran
  • Publication number: 20130217058
    Abstract: Methods are described for monitoring the amounts of PTH variants in a biological sample by digesting the sample to produce surrogate peptides specific to the targeted PTH variants, and detecting and quantifying the surrogate peptides by selective reaction monitoring (SRM) mass spectrometry, using a set of precursor-to-product ion transitions optimized for sensitivity and selectivity. The PTH variants, or a portion thereof, may be concentrated in the sample by means of immunoaffinity capture or other suitable technique. The mass spectrometric method described herein enables the concurrent measurement of peptides representative of a plurality of targeted PTH variants in a single assay.
    Type: Application
    Filed: February 25, 2013
    Publication date: August 22, 2013
    Inventors: Mary Frances LOPEZ, David A. SARRACINO, Amol PRAKASH, Randall W. NELSON, Paul ORAN, Bryan E. KRASTINS, Taha REZAI
  • Patent number: 8383417
    Abstract: Methods are described for monitoring the amounts of PTH variants in a biological sample by digesting the sample to produce surrogate peptides specific to the targeted PTH variants, and detecting and quantifying the surrogate peptides by selective reaction monitoring (SRM) mass spectrometry, using a set of precursor-to-product ion transitions optimized for sensitivity and selectivity. The PTH variants, or a portion thereof, may be concentrated in the sample by means of immunoaffinity capture or other suitable technique. The mass spectrometric method described herein enables the concurrent measurement of peptides representative of a plurality of targeted PTH variants in a single assay.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: February 26, 2013
    Assignees: Thermo Finnigan, LLC, Intrinsic Bioprobes, Inc.
    Inventors: Mary Frances Lopez, David A. Sarracino, Amol Prakash, Randall W. Nelson, Paul Oran, Bryan E. Krastins, Taha Rezai
  • Publication number: 20110250618
    Abstract: The present invention is directed to novel biomarkers and combinations thereof. The present invention also provides assays and data evaluation methods related to the detection and monitoring of diseases, particularly, diabetes. In particular, the biomakers in accordance with the present invention include, but are not limited to, modified forms of nominally wild-type proteins, such as Gc-Globulin or GcG (also known as Vitamin D binding protein), beta-2-microglobulin (b2m), cystatin C (cysC), Albumin and Hem A&B. Particular forms of diabetes contemplated by the methods of the present invention include, but are not limited to, type 1 diabetes (T1D), type 2 diabetes (T2DM), pre-T1D and pre-T2DM. The present invention also provides methods of detecting multiple biomarkers in a single assay and to employ data evaluation methods that is able to accurately use these data in the determination and monitoring of diseases, such as diabetes.
    Type: Application
    Filed: March 17, 2009
    Publication date: October 13, 2011
    Applicant: Arizona Board of Regents, for and on behalf of Arizona State University
    Inventors: Randall W. Nelson, Chad R. Borges, Paul Oran
  • Publication number: 20110151568
    Abstract: Methods are described for monitoring the amounts of PTH variants in a biological sample by digesting the sample to produce surrogate peptides specific to the targeted PTH variants, and detecting and quantifying the surrogate peptides by selective reaction monitoring (SRM) mass spectrometry, using a set of precursor-to-product ion transitions optimized for sensitivity and selectivity. The PTH variants, or a portion thereof, may be concentrated in the sample by means of immunoaffinity capture or other suitable technique. The mass spectrometric method described herein enables the concurrent measurement of peptides representative of a plurality of targeted PTH variants in a single assay.
    Type: Application
    Filed: December 22, 2009
    Publication date: June 23, 2011
    Inventors: Mary Frances Lopez, David A. Sarracino, Amol Prakash, Randall W. Nelson, Paul Oran, Bryan E. Krastins, Taha Rezai