Abstract: The present disclosure provides compounds of Formula I or II. Compounds of Formula I or II may be used in pharmaceutical formulations, and may be used for modulating glucocorticoid receptors.

Abstract: A composition for forming a polyurethane foam is provided using polyol having a total unsaturation less than 0.04 meq/g, methylene diphenyl diisocyanate (MDI), and epoxidized soybean oil. The epoxidized soybean oil may comprise greater than about 5% by weight of the composition. A method for forming polyurethane foam using the aforementioned composition is also provided.

Abstract: A device for evaporating a liquid such as liquid fuel. The device comprises: a shell; means for supplying heat to the shell; a porous wick located in the shell so that there is a gap between an outer surface side of the porous wick and an inner surface of the shell; means for supplying liquid to the porous wick; and an outlet in the shell for vapour produced in the gap by the application of heat from the shell to the liquid in the wick.

Abstract: System and method are provided where parcels or packages are associated or grouped, into logical group or logical containerization of parcels or packages, without need for physical container, such that parcels or packages can be tracked as a group, for example with a unique group ID. Logical group may be tracked within specified logical zone on conveyor, transported, sorted and/or otherwise processed as unique logical group without need to be contained in physical container. System and method for automated sortation can accumulate set number or set volume of packages, and then process the accumulated set number or volume of packages.

Abstract: A composite oxidation catalyst for use in an exhaust system for treating an exhaust gas produced by a vehicular compression ignition internal combustion engine is disclosed. The composite oxidation catalyst comprises a honeycomb flow-through substrate monolith and two catalyst washcoat zones arranged axially in series on and along the substrate surface.

Abstract: A counterflow heat transfer system comprises a heat exchanger and a flow controller arranged to convey a first fluid through the heat exchanger in a first flow direction and a second fluid through the heat exchanger in a second counterflow direction. The heat exchanger comprises at least one first thermally conductive tube conveying the first fluid and at least one second thermally conductive tube conveying the second fluid. The first and second tubes are wound around one another and in contact with one another in an entwined tubular arrangement.

Abstract: A fuel tank inerting system for an aircraft, the system comprises a catalytic heat exchanger comprising a first flow path and a second flow path for heat exchange with the first flow path. The system further comprises a first inlet arranged upstream of the first flow path of the catalytic heat exchanger for providing a mixture of fuel vapour and oxygen to the first flow path for sustaining a catalysed reaction, and a second inlet arranged upstream of the second flow path for providing a flow of fuel to the second flow path of the catalytic heat exchanger for exchanging heat with the first flow path.

Abstract: A system comprising (i) a vehicular compression ignition engine comprising one or more engine cylinders and one or more electronically-controlled fuel injectors therefor; (ii) an exhaust line for the engine comprising: a first emissions control device comprising a first honeycomb substrate, which comprises a hydrocarbon adsorbent component; and a second emissions control device comprising an electrically heatable element and a catalysed second honeycomb substrate, which comprises a rhodium-free platinum group metal comprising platinum, wherein the electrically heatable element is disposed upstream from the catalysed second honeycomb substrate and wherein both the electrically heatable element and the catalysed second honeycomb substrate are disposed downstream from the first honeycomb substrate; a third emissions control device, which is a third honeycomb substrate comprising an ammonia-selective catalytic reduction catalyst disposed downstream from the second emissions control device; and one or more tempera

Abstract: The present invention is directed to a method of preparing a synthetic crystalline material, designated as JMZ-12, with a framework built up by the disorder AEI and CHA structures, substantially free of framework phosphorous and prepared preferably in the absence of halides such as fluoride ions. Such method comprises the step of heating a reaction mixture under crystallization conditions for a sufficient period to form a disordered zeolite having both CHA and AEI topologies, wherein the reaction mixture comprises at least one source of aluminum, at least one source of silicon, a source of alkaline or alkaline-earth cations, and a structure directing agent containing at least one source of quaternary ammonium cations and at least one source of alkyl-substituted piperidinium cations in a molar ratio of 0.20 to about 1.4. The resulting zeolites are useful as catalysts, particularly when used in combination with exchanged transition metal(s) and, optionally, rare earth metal(s).

Abstract: A composite oxidation catalyst (18, 20) for use in an exhaust system for treating an exhaust gas produced by a vehicular compression ignition internal combustion engine (30) and upstream of a particulate matter filter (44, 50) in the exhaust system comprises a substrate (5) having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); and three or more catalyst washcoat zones (1, 2, 3; or 1, 2, 3, 4) arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1, wherein L1<L, is defined at one end by the first substrate end (I) and at a second end by a first end (19, 21) of a second catalyst washcoat zone (2) having a length L2, wherein L2<L, wherein the first catalyst washcoat zone (1) comprises a first refractory metal oxide support material and two or more platinum group metal components supported thereon comprising both platinum and palla

Abstract: A system (2) comprising (i) a vehicular compression ignition engine (1) comprising one or more engine cylinders and one or more electronically-controlled fuel injectors therefor; (ii) an exhaust line (3) for the engine comprising: a first emissions control device (5) comprising a first honeycomb substrate, which comprises a hydrocarbon adsorbent component; and a second emissions control device (7) comprising an electrically heatable element (7a) and a catalysed second honeycomb substrate (7b), which comprises a rhodium-free platinum group metal (PGM) comprising platinum, wherein the electrically heatable element (7a) is disposed upstream from the catalysed second honeycomb substrate (7b) and wherein both the electrically heatable element (7a) and the catalysed second honeycomb substrate (7b) are disposed downstream from the first honeycomb substrate; a third emissions control device (22), which is a third honeycomb substrate comprising an ammonia-selective catalytic reduction catalyst disposed downstream from

Abstract: A method of treating exhaust gas from a lean burn internal combustion engine is disclosed. The method comprises: introducing ammonia or an ammonia precursor into the exhaust gas upstream of an Fe-SCR catalyst, the Fe-SCR catalyst comprising iron and a zeolite; and contacting the exhaust gas with the Fe-SCR catalyst; wherein the amount of ammonia or ammonia precursor introduced into the exhaust gas upstream of the Fe-SCR catalyst is controlled to provide an ammonia-to-NOx molar ratio (ANR) in the exhaust gas contacting the Fe-SCR catalyst of from greater than 2 to 6.

Abstract: Methods and apparatus monitor health by detection of sleep stage. For example, a sleep stage monitor (100) may access sensor data signals related to bodily movement and/or respiration movements. At least a portion of the detected signals may be analyzed to calculate respiration variability. The respiration variability may include one or more of variability of respiration rate and variability of respiration amplitude. A processor may then determine a sleep stage based on one or more of respiration variability and bodily movement, such as with a combination of both. The determination of sleep stages may distinguish between deep sleep and other stages of sleep, or may differentiate between deep sleep, light sleep and REM sleep. The bodily movement and respiration movement signals may be derived from one or more sensors, such as non-invasive sensor (e.g., a non-contact radio-frequency motion sensor or a pressure sensitive mattress).

Abstract: A compression ignition internal combustion engine (30) for a heavy-duty diesel vehicle comprising an exhaust system (32) comprising a composite oxidation catalyst (12, 42) and a soot filter substrate (44, 50) disposed downstream from the composite oxidation catalyst comprising: a substrate (5), preferably a honeycomb flow-through substrate monolith, having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); two catalyst washcoat zones (1, 2) arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1 and comprising a first catalyst washcoat layer (9), wherein L1<L, is defined at one end by the first substrate end (I) and at a second end by a first end (15) of a second catalyst washcoat zone (2) having a length L2 and comprising a second catalyst washcoat layer (11), wherein L2<L, wherein the second catalyst washcoat zone (2) is defined a

Abstract: Provided herein is a corneal topography system (218) that utilizes a prism placed in optical alignment between the pattern generator (201), such as a Placido disk, and the eye. The corneal topography system may be a prismatic triangulating corneal topography system that utilizes light rays of angle ? at the edge of the prism not passing through the prism (202), and using the deviation of the light rays passing through the prism at that edge to calculate angle ?. With angle ? calculated from the reflected image on the image sensor (209) intersecting with the light ray from the pattern generator (201) at angle ? at the reflection point on the corneal surface (207). This provides both the position and slope of the corneal surface (207) at that point. Also provided is a method for mapping a corneal surface of an eye of a subject utilizing an optical prism (202) to produce a reflection image from a corneal surface reflection point (206) on the corneal surface (207) of the eye.

Abstract: A processing system includes methods to promote sleep. The system may include a monitor such as a non-contact motion sensor from which sleep information may be determined. User sleep information, such as sleep stages, hypnograms, sleep scores, mind recharge scores and body scores, may be recorded, evaluated and/or displayed for a user. The system may further monitor ambient and/or environmental conditions corresponding to sleep sessions. Sleep advice may be generated based on the sleep information, user queries and/or environmental conditions from one or more sleep sessions. Communicated sleep advice may include content to promote good sleep habits and/or detect risky sleep conditions. In some versions of the system, any one or more of a bedside unit 3000 sensor module, a smart processing device, such as a smart phone or smart device 3002, and network servers may be implemented to perform the methodologies of the system.

Abstract: A child-resistant storage case has a lid hinged to a base to define an interior storage space. Two side latches are spaced apart from one another on opposing side aspects of the storage case. A front latch mechanism includes a horizontal tab extending forward from the front aspect of the case. To open the storage case, the user must simultaneously press inward on the side latches, press downward on the horizontal tab, and lift the lid upward. The required downward actuation of the front latch mechanism is counter-intuitive for most people, and in combination with the side latches, is very difficult for most small children.

Abstract: Systems and methods are provided for rendering a first interface for presentation by a user computing device based on a first user input and information received over a network. The first interface can include item information. Additional item information may be stored at the user computing device at the time that the first interface is processed, but not initially displayed. Based on receiving a second user input, a second interface can be displayed that includes the additional item information, where the second interface may be displayed over a first portion of the first interface such that the first user interface remains accessible. The second interface may be populated with portions of the previously stored additional item information without necessarily obtaining further information over the network.

Abstract: The present disclosure relates to a method and apparatus for cleaning a 3D printed article, in particular a 3D printed heat exchanger. After 3D printing, an article may have internal passages formed from bonded powder and said passages may contain unbonded powder that needs to be removed before further use of/processing of the article. To remove this unbonded powder, the article is filled with a cleaning fluid and vibrated. The cleaning fluid is then pumped out of the article and past a sensor that generates a magnetic field. The sensor detects the presence of powder particles in the fluid by detecting a perturbation of the magnetic field caused by said particles. The fluid is then filtered and returned to a reservoir for use. The sensor may indicate the article is sufficiently clean when a detected concentration of particles in the fluid drops below a threshold.