Patents by Inventor Paul Pieper

Paul Pieper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170340645
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: August 16, 2017
    Publication date: November 30, 2017
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER, Andreas SCHNAPP
  • Publication number: 20170216298
    Abstract: This invention relates to the B2-adrenoceptor agonist Olodaterol or a pharmaceutically acceptable salt thereof, for use in a method of treatment of cough from various origins.
    Type: Application
    Filed: April 20, 2017
    Publication date: August 3, 2017
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER
  • Publication number: 20170128455
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: January 23, 2017
    Publication date: May 11, 2017
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER, Andreas SCHNAPP
  • Publication number: 20160287600
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: June 9, 2016
    Publication date: October 6, 2016
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER, Andreas SCHNAPP
  • Publication number: 20160074410
    Abstract: This invention relates to the ?2-adrenoceptor agonist Olodaterol or a pharmaceutically acceptable salt thereof, for use in a method of treatment of cough from various origins.
    Type: Application
    Filed: November 24, 2015
    Publication date: March 17, 2016
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER
  • Publication number: 20150086489
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C14-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: December 3, 2014
    Publication date: March 26, 2015
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER, Andreas SCHNAPP
  • Publication number: 20140286879
    Abstract: A pharmaceutical composition comprising: (a) a compound of formula 1 wherein: n is 1 or 2; R1 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; R2 is hydrogen, halogen, C1-4-alkyl, or O—C1-4-alkyl; and R3 is hydrogen, C1-4-alkyl, OH, halogen, O—C1-4-alkyl, O—C1-4-alkylene-COOH, or O—C1-4-alkylene-COO—C1-4-alkyl, or an enantiomer, mixture of enantiomers, or racemate thereof, or an acid addition salt with pharmacologically acceptable acids thereof, or a solvate or hydrate thereof; and (b) another active substance 2, wherein the molar ratio of the compound of formula 1 to the active substance 2 is 1:10 to 12:1.
    Type: Application
    Filed: June 12, 2014
    Publication date: September 25, 2014
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER, Andreas SCHNAPP
  • Publication number: 20140100222
    Abstract: This invention relates to the ?2-adrenoceptor agonist Olodaterol or a pharmaceutically acceptable salt thereof, for use in a method of treatment of cough from various origins.
    Type: Application
    Filed: October 8, 2013
    Publication date: April 10, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Thierry BOUYSSOU, Michael Paul PIEPER
  • Patent number: 7652138
    Abstract: A compound of formula 1 wherein: A is a group selected from X? is an anion with a single negative charge; R1 and R2 are each independently a C1-C4-alkyl optionally substituted with hydroxy or halogen; and R3, R4, R5, R6, R7, and R8 are each independently hydrogen, C1-C4-alkyl, C1-C4-alkyloxy, hydroxy, CF3, CN, NO2, or halogen, with the proviso that at least one of the groups R3, R4, R5, R6, R7, and R8 is not hydrogen, processes for preparing these compounds, pharmaceutical compositions containing these compounds, and their use as pharmaceutical compositions.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: January 26, 2010
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck
  • Patent number: 7569581
    Abstract: The present invention relates to new anticholinergics of general formula 1 wherein A, X?, and the groups R1, R2, R3, R4, R5, R6 and R7 may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharmaceutical compositions.
    Type: Grant
    Filed: April 28, 2005
    Date of Patent: August 4, 2009
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Rolf Banholzer
  • Patent number: 7244742
    Abstract: A pharmaceutical composition comprising: (a) an anticholinergic of formula 1 wherein X? is an anion with a single negative charge; (b) a corticosteroid; and (c) a betamimetic, wherein each component (a), (b), and (c) are optionally in the form of the solvates or hydrates thereof, processes for preparing them, and their use in the treatment of respiratory diseases.
    Type: Grant
    Filed: July 23, 2003
    Date of Patent: July 17, 2007
    Assignee: Boehringer Ingelheim Pharma GmbH & Co KG
    Inventors: Michael Paul Pieper, Christopher John Montague Meade, Michel Pairet
  • Patent number: 6852728
    Abstract: A compound of formula 1 wherein: A is a group selected from X? is an anion with a single negative charge; R1 and R2 are each independently a C1-C4-alkyl optionally substituted with hydroxy or halogen; and R3, R4, R5, R6, R7, and R8 are each independently hydrogen, C1-C4-alkyl, C1-C4-alkyloxy, hydroxy, CF3, CN, NO2, or halogen, with the proviso that at least one of the groups R3, R4, R5, R6, R7, and R8 is not hydrogen, processes for preparing these compounds, pharmaceutical compositions containing these compounds, and their use as pharmaceutical compositions.
    Type: Grant
    Filed: September 28, 2001
    Date of Patent: February 8, 2005
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck
  • Publication number: 20040228805
    Abstract: A pharmaceutical composition comprising:
    Type: Application
    Filed: July 23, 2003
    Publication date: November 18, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Michael Paul Pieper, Christopher John Montague Meade, Michel Pairet
  • Publication number: 20040087617
    Abstract: The present invention relates to new anticholinergics of general formula 1 1
    Type: Application
    Filed: October 14, 2003
    Publication date: May 6, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Rolf Banholzer
  • Patent number: 6706726
    Abstract: The present invention relates to new anticholinergics of general formula 1: wherein A, X− and the groups R1, R2, R3, R4, R5, R6 and R7 may have the meanings given in the claims and in the specification, processes for preparing them and their use as pharamaceutical compositions.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: March 16, 2004
    Assignee: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Rolf Banholzer
  • Publication number: 20030087941
    Abstract: The invention relates to the use of dopamine receptor agonists for preparing a pharmaceutical composition for the reduction of excessive food intake.
    Type: Application
    Filed: September 27, 2002
    Publication date: May 8, 2003
    Applicant: Boehringer Ingelheim Pharma KG
    Inventors: Michael Paul Pieper, Joachim Mierau
  • Publication number: 20020119991
    Abstract: A compound of formula 1 1
    Type: Application
    Filed: September 28, 2001
    Publication date: August 29, 2002
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck
  • Publication number: 20020115680
    Abstract: The present invention relates to new anticholinergics of general formula 1 1
    Type: Application
    Filed: October 11, 2001
    Publication date: August 22, 2002
    Inventors: Helmut Meissner, Gerd Morschhaeuser, Michael Paul Pieper, Gerald Pohl, Richard Reichl, Georg Speck, Rolf Banholzer
  • Patent number: 4379417
    Abstract: A cutting tool arrangement for performing the process of opening up the slit cut in the workpiece by circular saws before the saw is retracted to facilitate removal of the saw. The workpiece being severed is moved perpendicular to the cutting plane as is the saw blade to accomplish the desired result.
    Type: Grant
    Filed: May 4, 1981
    Date of Patent: April 12, 1983
    Assignee: Rolf Peddinghaus
    Inventors: Paul Pieper, Walter Cordier
  • Patent number: 4289054
    Abstract: A cutting tool arrangement for performing the process of opening up the slit cut in the workpiece by circular saws before the saw is retracted to facilitate removal of the saw. The workpiece being severed is moved perpendicular to the cutting plane as is the saw blade to accomplish the desired result.
    Type: Grant
    Filed: August 30, 1979
    Date of Patent: September 15, 1981
    Assignee: Rolf Peddinghaus
    Inventors: Paul Pieper, Walter Cordier