Patents by Inventor Paul Powell BEROZA

Paul Powell BEROZA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compounds and methods of use
    Patent number: 11787775
    Abstract: The invention relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: October 17, 2023
    Assignee: Genentech, Inc.
    Inventors: Jason R. Zbieg, Paul Powell Beroza
  • HETEROBIFUNCTIONAL MOLECULES AS TEAD INHIBITORS
    Publication number: 20230242506
    Abstract: The invention relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: September 2, 2022
    Publication date: August 3, 2023
    Applicant: GENENTECHT, INC.
    Inventors: Jason Robert Zbieg, Elisia Villemure, Joachim Rudolph, Paul Powell Beroza, James John Crawford
  • THERAPEUTIC COMPOUNDS AND METHODS OF USE
    Publication number: 20230203062
    Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: November 21, 2022
    Publication date: June 29, 2023
    Applicant: Genentech, Inc.
    Inventors: Jason Robert ZBIEG, Paul Powell BEROZA, Vishal Anil VERMA, Bing-Yan ZHU, Ramsay BEVERIDGE, Liang ZHAO, Melissa LEBLANC, Lisa Marie BARTON, Bryan Ka Ip CHAN, Samir BOUAYAD-GERVAIS, Anwesha DEY, Marie Anne EVANGELISTA, Russell Tyler SMITH
  • THERAPEUTIC COMPOUNDS AND METHODS OF USE
    Publication number: 20230202984
    Abstract: This disclosure relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: November 21, 2022
    Publication date: June 29, 2023
    Applicant: Genentech, Inc.
    Inventors: Jason Robert Zbieg, Russell Tyler Smith, Paul Powell Beroza, Vishal Anil Verma, Bing-Yan Zhu, Ramsay Beveridge, Lisa Marie Barton, Bryan Ka lp Chan, Curtis Colwell, Samir Bouayad-Gervais, Anwesha Dey, Marie Anne Evangelista
  • THERAPEUTIC COMPOUNDS AND METHODS OF USE
    Publication number: 20230054741
    Abstract: The invention relates to compounds and methods of using said compounds, as well as pharmaceutical compositions containing such compounds, for treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: July 22, 2021
    Publication date: February 23, 2023
    Applicant: Genentech, Inc.
    Inventors: Jason R. Zbieg, Paul Powell Beroza
  • THERAPEUTIC COMPOUNDS
    Publication number: 20210238184
    Abstract: The present disclosure relates to compounds of formula (I): and pharmaceutically acceptable salts thereof, wherein R1-R3 have any of the values defined herein, and compositions and uses thereof. The compounds are useful as inhibitors of the YAP:TEAD protein:protein interaction. Also included are pharmaceutical compositions comprising a compound of formula (I) or a pharmaceutically acceptable salt thereof, and methods of using such compounds and salts in the treatment of various YAP:TEAD-mediated disorders, including cancer.
    Type: Application
    Filed: November 25, 2020
    Publication date: August 5, 2021
    Applicant: Genentech, Inc.
    Inventors: Jason Robert Zbieg, Paul Powell Beroza, James John Crawford
  • CARBOXAMIDE AND SULFONAMIDE DERIVATIVES USEFUL AS TEAD MODULATORS
    Publication number: 20210188775
    Abstract: The invention is concerned with the compounds of formula (I) and formula (II): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of using the compounds of formula (I) and formula (II) as well as pharmaceutical compositions containing such compounds. The compounds are useful in treating diseases and conditions mediated by TEAD, such as cancer.
    Type: Application
    Filed: March 2, 2021
    Publication date: June 24, 2021
    Applicant: Genentech, Inc.
    Inventors: Christian CUNNINGHAM, Paul Powell BEROZA, James John CRAWFORD, Wendy Lee, Olivier RENE, Jason Robert ZBIEG, Jiangpeng LIAO, Tao WANG, Chen YU