Patents by Inventor Paul Predki

Paul Predki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10457937
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: October 29, 2019
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF SOUTHERN CALIFORNIA, CURATE BIOSCIENCES LLC
    Inventors: Emil P. Kartalov, Cheng-Chung Lee, Paul Predki
  • Patent number: 10174313
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: January 8, 2019
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF SOUTHERN CALIFORNIA, CURATE BIOSCIENCES LLC
    Inventors: Emil P. Kartalov, Cheng-Chung Lee, Paul Predki
  • Publication number: 20180171330
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Application
    Filed: January 31, 2018
    Publication date: June 21, 2018
    Inventors: Emil P. KARTALOV, Cheng-Chung LEE, Paul PREDKI
  • Publication number: 20180171331
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Application
    Filed: January 31, 2018
    Publication date: June 21, 2018
    Inventors: Emil P. KARTALOV, Cheng-Chung LEE, Paul PREDKI
  • Patent number: 9920315
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: March 20, 2018
    Assignees: CALIFORNIA INSTITUTE OF TECHNOLOGY, UNIVERSITY OF SOUTHERN CALIFORNIA, CURATE BIOSCIENCES LLC
    Inventors: Emil P. Kartalov, Cheng-Chung Lee, Paul Predki
  • Publication number: 20160208242
    Abstract: Provided herein are devices and methods for the micro-isolation of biological cellular material. A micro-isolation device described can comprise a photomask that protects regions of interest against DNA-destroying illumination. The micro-isolation device can further comprise photosensitive material defining access wells following illumination and subsequent developing of the photosensitive material. The micro-isolation device can further comprise a chambered microfluidic device comprising channels providing access to wells defined in photosensitive material. The micro-isolation device can comprise a chambered microfluidic device without access wells defined in photosensitive material where valves control the flow of gases or liquids through the channels of the microfluidic device.
    Type: Application
    Filed: January 15, 2016
    Publication date: July 21, 2016
    Inventors: Emil P. KARTALOV, Cheng-Chung LEE, Paul PREDKI
  • Publication number: 20160061774
    Abstract: The present teachings provide methods, devices, systems, and materials for performing electrophoresis in an automated fashion. The electrophoresis system may simultaneously image gel during an electrophoresis run. In some embodiments, the electrophoresis system may analyze an imaged gel during or after electrophoresis. The device may comprise a gel processing system, a gel illumination system, an image capture system, and an image analysis all housed within a housing.
    Type: Application
    Filed: August 3, 2015
    Publication date: March 3, 2016
    Inventors: Timothy UPDYKE, Paul PREDKI, Evangeline GONZALEZ, Randall LOWE, Tad SIMONS
  • Patent number: 9097663
    Abstract: The present teachings provide methods, devices, systems, and materials for performing electrophoresis in an automated fashion. The electrophoresis system may simultaneously image gel during an electrophoresis run. In some embodiments, the electrophoresis system may analyze an imaged gel during or after electrophoresis. The device may comprise a gel processing system, a gel illumination system, an image capture system, and an image analysis all housed within a housing.
    Type: Grant
    Filed: December 17, 2012
    Date of Patent: August 4, 2015
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Timothy Updyke, Paul Predki, Evangeline Gonzalez, Randall Lowe, Tad Simons
  • Publication number: 20120247958
    Abstract: The present teachings describe gel processing systems comprising at least an electrophoresis device and a computer system operably linked to perform electrophoresis. Systems of the disclosure may also comprise gel imaging systems, image capture systems, gel illumination systems and/or gel/image analysis systems. A computer system of the disclosure may comprise software components including graphical user interface (GUI) specifications and functional specifications. The disclosure also describes methods for gel processing performed on a gel processing system. Methods of the disclosure may comprise performing electrophoresis and in some embodiments, one or more additional steps, such as imaging, analysis, report generation and transfer of data to external sources. Methods and workflows of the disclosure may be user controlled and customized by using the GUI and other software and hardware functional components of the computer system.
    Type: Application
    Filed: April 2, 2012
    Publication date: October 4, 2012
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Timothy Updyke, Paul Predki, Evangeline Gonzalez, Randall Lowe, Tad Simons
  • Publication number: 20110042213
    Abstract: The present teachings provide methods, devices, systems, and materials for performing electrophoresis in an automated fashion. The electrophoresis system may simultaneously image gel during an electrophoresis run. In some embodiments, the electrophoresis system may analyze an imaged gel during or after electrophoresis. The device may comprise a gel processing system, a gel illumination system, an image capture system, and an image analysis all housed within a housing.
    Type: Application
    Filed: August 24, 2010
    Publication date: February 24, 2011
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Timothy UPDYKE, Paul PREDKI, Evangeline GONZALEZ, Randall LOWE, Tad SIMONS
  • Publication number: 20070042421
    Abstract: Disclosed are methods for identifying nucleic acids in a sample of nucleic acids in which nucleic acids are initially present in unequal amounts. The methods include partitioning the starting population of nucleic acids to form one or more subpopulations, and then identifying nucleic acids that are present in different amounts in the partitioned nucleic acid sample as compared to the starting population.
    Type: Application
    Filed: November 1, 2006
    Publication date: February 22, 2007
    Inventors: Jonathan Rothberg, Michael McKenna, Paul Predki, Andreas Windemuth, Richard Shimkets
  • Publication number: 20060223131
    Abstract: The present invention provides human protein arrays that include at least 1000 human proteins. In another embodiment, the present invention provides a method for identifying a substrate of an enzyme, comprising contacting the enzyme with a positionally addressable array comprising at least 100 proteins immobilized on functionalized glass surface, and identifying a protein on the positionally addressable array that is bound and/or modified by the enzyme, wherein a binding or modifying of the protein by the enzyme indicates that the protein is a substrate for the enzyme. In additional embodiments, provided herein are methods for making an array of at least 1000 human proteins under non-denaturing conditions, including human proteins that are difficult to express and/or difficult to isolate in a non-denatured state.
    Type: Application
    Filed: September 15, 2005
    Publication date: October 5, 2006
    Inventors: Barry Schweitzer, James Ball, Paul Predki, Fang Zhou, Gregory Michaud
  • Publication number: 20060141529
    Abstract: It has been determined Cortactin interacts with an ARG/ABL protein kinase. Thus, provided herein are compositions, kits and assays containing reagents directed to Cortactin and an ARG/ABL protein kinase.
    Type: Application
    Filed: July 27, 2005
    Publication date: June 29, 2006
    Inventors: Anthony Koleske, Scott Boyle, Greg Michaud, Barry Schweitzer, Paul Predki
  • Publication number: 20060099704
    Abstract: The present application relates to methods for providing a protein microarray product and related products and services to a customer, methods, kits, and systems for labeling a probe for a protein microarray, and methods for determining protein concentrations using a protein microarray. The methods for providing a protein micorarray can include, in certain aspects, a computer function for performing some of the steps of the methods. Methods and kits for labeling a probe can include a control array that includes a molecule that binds to a label of a probe.
    Type: Application
    Filed: July 14, 2005
    Publication date: May 11, 2006
    Inventors: Paul Predki, Barry Schweitzer
  • Publication number: 20050129678
    Abstract: The invention provides methods for the prediction of an epitope in a target protein. An epitope of the target protein can be bound by a given molecule, e.g., by an antibody. In particular, the methods of the invention comprise (i) identifying a plurality of cross-reactive proteins, i.e., proteins that can be bound by the same molecule, e.g., by the same antibody, as the target protein using, e.g., protein microarrays; and (ii) comparing the amino acid sequences of the target protein and the cross-reactive proteins with each other to identify windows of sequence homology, wherein the windows of sequence homology correspond to the epitope.
    Type: Application
    Filed: July 19, 2004
    Publication date: June 16, 2005
    Inventors: Paul Predki, Hong Guo
  • Patent number: D667134
    Type: Grant
    Filed: April 1, 2011
    Date of Patent: September 11, 2012
    Assignee: Life Technologies Corporation
    Inventors: Timothy Updyke, Paul Predki, Evangeline Gonzalez, Randall Lowe, Tad Simons
  • Patent number: D695418
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: December 10, 2013
    Assignee: Life Technologies Corporation
    Inventors: Timothy Updyke, Paul Predki, Evangeline Gonzalez, Randall Lowe, Tad Simons
  • Patent number: D719277
    Type: Grant
    Filed: June 1, 2012
    Date of Patent: December 9, 2014
    Assignee: Life Technologies Corporation
    Inventors: Jennifer Miller, Paul Predki, Timothy Updyke, Itay Sela, Shimon Spector
  • Patent number: D795449
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: August 22, 2017
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Jennifer Miller, Paul Predki, Timothy Updyke, Itay Sela, Shimon Spector
  • Patent number: D831847
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: October 23, 2018
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Jennifer Miller, Paul Predki, Timothy Updyke, Itay Sela, Shimon Spector