Patents by Inventor Paul R. Augustine

Paul R. Augustine has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method and apparatus for measuring the volume of an animal paw
    Patent number: 7735366
    Abstract: Disclosed is an improved method for measuring the volume of an animal paw, suitable for use in a rat paw edema assay. Also disclosed is a novel apparatus for measuring the volume of liquid displaced by the insertion of an object into a liquid filled cup (1) which is on a cup holder basin (3), the liquid filled cup and cup holder basin being inside a rectangular support assembly (5), the measurement obtained by determining the buoyant force produced as a result of the displacement of the liquid by the animal paw.
    Type: Grant
    Filed: May 6, 2006
    Date of Patent: June 15, 2010
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Gary S. Kath, Michael K. Wismer, Paul R. Augustine, Cordelia G. Rasa
  • METHOD AND APPARATUS FOR MEASURING THE VOLUME OF AN ANIMAL PAW
    Publication number: 20090282913
    Abstract: Disclosed is an improved method for measuring the volume of an animal paw, suitable for use in a rat paw edema assay. Also disclosed is a novel apparatus for measuring the volume of liquid displaced by the insertion of an object into a liquid filled cup (1) which is on a cup holder basin (3), the liquid filled cup and cup holder basin being inside a rectangular support assembly (5), the measurement obtained by determining the buoyant force produced as a result of the displacement of the liquid by the animal paw.
    Type: Application
    Filed: May 5, 2006
    Publication date: November 19, 2009
    Inventors: Gary S. Kath, Michael K. Wismer, Paul R. Augustine, Cordelia G. Rasa
  • Electrical field stimulation of eukaryotic cells
    Patent number: 7276206
    Abstract: Methods of identifying activators and inhibitors of voltage-gated ion channels are provided in which the methods employ electrical field stimulation of the cells in order to manipulate the open/close state transition of the voltage-gated ion channels. This allows for more convenient, more precise experimental manipulation of these transitions, and, coupled with efficient methods of detecting the result of ion flux through the channels, provides methods that are especially suitable for high throughput screening.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: October 2, 2007
    Assignee: Merck & Co., Inc.
    Inventors: Paul R. Augustine, Randal M. Bugianesi, Gary S. Kath, Owen B. McManus, Paul B. Bennett, Tina A. Garyantes, John P. Imredy