Patents by Inventor Paul R. Klaiber
Paul R. Klaiber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11666523Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patients tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.Type: GrantFiled: August 22, 2018Date of Patent: June 6, 2023Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Yizhong Wang, Tiffany T. Ton, Carola A. Carrera Vidal, Joel D. Oxman, Jennifer J. Post, Paul R. Klaiber
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Publication number: 20230134622Abstract: A method of applying a two-part dental sealant is described comprising providing a syringe device (1) comprising a cartridge (10) including first and second chamber. The first chamber contains a first part of a dental sealant comprising a (meth)acrylate resin and an oxidizing curing agent. The second chamber contains a second part of a dental sealant comprising a (meth)acrylate resin and a reducing curing agent that reacts with the oxidizing curing agent of the first chamber. The first and/or second part of the dental sealant further comprise a single component or multiple components that neutralize acid and promote remineralization. The syringe device comprises a dispensing nozzle (17) comprising a static mixer and an outlet at one end of the cartridge and a plunger (20) at the opposing end of the cartridge. Also described is a kit for storing and applying the dental sealant is described.Type: ApplicationFiled: June 4, 2019Publication date: May 4, 2023Inventors: Randilynn B. Christensen, Kenton D. Budd, Afshin Falsafi, Mahmut Aksit, Jana Ninkovic, Jie J. Liu, Mark B. Agre, Masayuki Nakamura, Jason W. Bjork, Bradley D. Craig, Richard P. Rusin, Paul J. Homnick, Joel D. Oxman, Yizhong Wang, Paul R. Klaiber, Bill H. Dodge
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Publication number: 20230110368Abstract: A method of removing calculus from a tooth is described comprising: applying aqueous compositions A and B to the tooth surface, wherein the composition A comprises hydrogen peroxide or a precursor thereto and composition B comprises catalase and a stabilizer comprising hydroxyl groups; and removing at least a part of the calculus from the tooth surface. Preferred stabilizers include dipropylene glycol and 1,3 propane diol. Also described are aqueous compositions and kits.Type: ApplicationFiled: September 20, 2022Publication date: April 13, 2023Inventors: Petra L. Kohler Riedi, Steven P. Swanson, Paul R. Klaiber
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Publication number: 20230000596Abstract: A method for making a dental appliance configured to position at least one tooth of a patient includes printing a hardenable liquid resin composition on a major surface of a polymeric material to form a pattern thereon, wherein the hardenable liquid resin composition includes a glass ionomer, a resin modified glass ionomer, and mixtures and combinations thereof. A dental appliance is formed from the polymeric material that includes an arrangement of cavities configured to receive one or more teeth.Type: ApplicationFiled: December 23, 2020Publication date: January 5, 2023Inventors: Bhaskar V. Velamakanni, Paul R. Klaiber, Richard P. Rusin, Yizhong Wang, Kevin T. Reddy, Matthew S. Stay, Matthew R.D. Smith, Jennifer J. Post
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Publication number: 20220211603Abstract: A composition comprising from 1 wt-% to 3 wt-% total of glucosamine a derivative of glucosamine, or a combination thereof based on the total weight of the composition, and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula (I): HOCH2—(OHOH)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3 and SO2R4 with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group and an aralkyl group, wherein n is an integer from 2 to 5.Type: ApplicationFiled: May 18, 2020Publication date: July 7, 2022Inventors: Richard P. Rusin, Jie Yang, Petra L. Kohler Riedi, Jodi L. Connell, Ingo Haeberlein, Hannah C. Cohen, Katie F. Wlaschin, Paul R. Klaiber, Yizhong Wang, Joel D. Oxman, Tiffany T. Ton, Roxanne A. Boehmer
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Patent number: 11377263Abstract: A dispenser (1) for liquids includes a reservoir (100) defining a volume (V100) for housing a liquid (150); a delivery tube (200) with a first end (201) attached to the reservoir, and a second end (202) distal from the reservoir, the delivery tube including a passage (203) in fluid communication with the volume of the reservoir and extending away from the reservoir; an applicator element (300) including an applicator tip (320) and a base (310) attached to the second end of the delivery tube, the applicator tip having a plurality of fingers (322) extending away from the base to a distal end of the applicator element distal from the delivery tube; and a removable seal (340), wherein removal of the removable seal creates an opening in the passage at a location upstream of the applicator tip and a fluid distribution channel between the fingers.Type: GrantFiled: November 1, 2018Date of Patent: July 5, 2022Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Henry C. Gydesen, Paul R. Klaiber, Yizhong Wang, Bruce R. Broyles
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Publication number: 20220192953Abstract: A composition comprising: from 0.2 wt-% to 3 wt-% total of arginine, glycine, or a combination thereof based on the total weight of the composition; and from 0.3 wt-% to 3 wt-% total of one or more surfactants, based on the total weight of the composition, of Formula I: HOCH2—(CHOH)n—CH2NR1R2 (I) wherein R1 and R2 are independently selected from the group consisting of a hydrogen atom, an alkyl group, C(O)R3, and SO2R4; with R3 and R4 being independently selected from the group consisting of an alkyl group, an aryl group, and an aralkyl group; wherein n is an integer from about 2 to about 5.Type: ApplicationFiled: May 20, 2020Publication date: June 23, 2022Inventors: Richard P. Rusin, Jie Yang, Petra L. Kohler Riedi, Jodi L. Connell, Ingo Haeberlein, Katie F. Wlaschin, Hannah C. Cohen, Tiffany T. Ton, Paul R. Klaiber, Yizhong Wang, Joel D. Oxman
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Patent number: 11337902Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.Type: GrantFiled: May 11, 2020Date of Patent: May 24, 2022Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Yizhong Wang, Tiffany T. Ton, Melinda B. Gustafson, Jennifer Post, Paul R. Klaiber, Carola A. Carrera Vidal, Joel D. Oxman
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Publication number: 20210353387Abstract: A dental appliance is described, the dental appliance including a polymeric substrate with a plurality of cavities for receiving one or more teeth, an arrangement of engineered microstructures on the substrate wherein the engineered microstructures include a therapeutic agent. The microstructures may be three-dimensionally engineered on a polymeric film disposed on a major surface of the polymeric substrate, wherein the microstructures extend outwards from the surface. The microstructures also comprise a compound releasable from the three-dimensionally engineered microstructures over a predetermined patient wear time.Type: ApplicationFiled: October 11, 2019Publication date: November 18, 2021Inventors: Bhaskar V. Velamakanni, Paul R. Klaiber, Richard P. Rusin, Daniel J. Skamser, Negus B. Adefris
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Publication number: 20210228315Abstract: A hardenable (e.g. dental) compositions is described comprising an encapsulated material. The encapsulated material comprises a basic core material and an inorganic shell material having certain viscosity criteria. Also described are dispensing devices and kits are described comprising a hardenable (e.g. dental) composition comprising a liquid material and an encapsulated material wherein the encapsulated material comprises a basic core material and an inorganic shell material comprising a metal oxide surrounding the core. The dispensing devices and kits can facilitate the methods of applying the hardenable composition. The hardenable or hardened (e.g. cured) composition can provide various technical effects such as a delayed release of a basic core material, a delayed increase in basicity, promoting remineralization of a tooth or bone structure, and increasing the average alkaline phosphatase (ALP) activity of pulp cells. In some embodiments, the composition is a dental (e.g.Type: ApplicationFiled: June 5, 2019Publication date: July 29, 2021Inventors: Randilynn B. Christensen, Kenton D. Budd, Afshin Falsafi, Mahmut Aksit, Jana Ninkovic, Jie J. Liu, Mark B. Agre, Masayuki Nakamura, Jason W. Bjork, Bradley D. Craig, Richard P. Rusin, Paul J. Homnick, Joel D. Oxman, Yizhong Wang, Paul R. Klaiber
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Publication number: 20200307863Abstract: A dispenser (1) for liquids includes a reservoir (100) defining a volume (V100) for housing a liquid (150); a delivery tube (200) with a first end (201) attached to the reservoir, and a second end (202) distal from the reservoir, the delivery tube including a passage (203) in fluid communication with the volume of the reservoir and extending away from the reservoir; an applicator element (300) including an applicator tip (320) and a base (310) attached to the second end of the delivery tube, the applicator tip having a plurality of fingers (322) extending away from the base to a distal end of the applicator element distal from the delivery tube; and a removable seal (340), wherein removal of the removable seal creates an opening in the passage at a location upstream of the applicator tip and a fluid distribution channel between the fingers.Type: ApplicationFiled: November 1, 2018Publication date: October 1, 2020Inventors: Henry C. Gydesen, Paul R. Klaiber, Yizhong Wang, Bruce R. Broyles
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Publication number: 20200268625Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.Type: ApplicationFiled: May 11, 2020Publication date: August 27, 2020Inventors: Yizhong Wang, Tiffany T. Ton, Melinda B. Gustafson, Jennifer Post, Paul R. Klaiber, Carola A. Carrera Vidal, Joel D. Oxman
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Publication number: 20200197289Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.5 wt-% to 4.8 wt-% of a water-soluble cationic N-containing polymer, a pharmaceutically acceptable buffer, 1.0 wt-% to 2.5 wt-% of sodium fluoride; and at least 60 wt-% water, wherein the weight percentages are based on the total weight of the aqueous composition.Type: ApplicationFiled: August 22, 2018Publication date: June 25, 2020Inventors: Yizhong Wang, Tiffany T. Ton, Carola A. Carrera Vidal, Joel D. Oxman, Jennifer J. Post, Paul R. Klaiber
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Patent number: 10682300Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.Type: GrantFiled: October 1, 2018Date of Patent: June 16, 2020Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Yizhong Wang, Tiffany T. Ton, Melinda B. Gustafson, Jennifer Post, Paul R. Klaiber, Carola A. Carrera Vidal, Joel D. Oxman
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Publication number: 20190183621Abstract: A method of applying a dental treatment composition to a patient's teeth, including selecting a dental treatment composition, applying the dental treatment composition to a surface of at least one tooth of the patient; and applying pressurized gas on the dental treatment composition to spread the dental treatment composition smoothly across the surface of the tooth.Type: ApplicationFiled: November 28, 2018Publication date: June 20, 2019Inventors: Bruce R. Broyles, Paul R. Klaiber, Jennifer Post
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Publication number: 20190099338Abstract: An aqueous oral care fluoride treatment composition, a method of providing fluoride to a patient's tooth surface, and a method of reducing the incidence of dental caries, wherein the composition includes: 0.1 wt-% to 3.0 wt-% of a crosslinked poly acid having carboxylic acid side groups; a pharmaceutically acceptable buffer; 1.0 wt-% to 2.5 wt-% of sodium fluoride; 0.025 wt-% to 1.75 wt-% of a multivalent cation salt; and at least 60 wt-% water; wherein the weight percentages are based on the total weight of the aqueous composition.Type: ApplicationFiled: October 1, 2018Publication date: April 4, 2019Inventors: Yizhong Wang, Tiffany T. Ton, Melinda B. Gustafson, Jennifer Post, Paul R. Klaiber, Carola A. Carrera Vidal, Joel D. Oxman
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Patent number: 10064802Abstract: An oral composition and a method of delivering an oral composition to a dental structure are described. The oral composition can include a solvent; an acidic copolymer having acidic acrylate monomeric units, acidic methacrylate monomeric units, or a combination thereof; a neutral copolymer having neutral acrylate monomeric units, neutral methacrylate monomeric units, or a combination thereof; and optionally an active agent. The acidic and neutral copolymers can be dissolved in the oral composition and the oral composition can form a film on a surface when contacted with an aqueous solution.Type: GrantFiled: September 10, 2014Date of Patent: September 4, 2018Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Yizhong Wang, Joel D. Oxman, Paul R. Klaiber, Jie J. Liu, Joanne A. Fitch, Tiffany T. Ton, Reinhold Hecht
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Publication number: 20160220473Abstract: An oral composition and a method of delivering an oral composition to a dental structure are described. The oral composition can include a solvent; an acidic copolymer having acidic acrylate monomeric units, acidic methacrylate monomeric units, or a combination thereof; a neutral copolymer having neutral acrylate monomeric units, neutral methacrylate monomeric units, or a combination thereof; and optionally an active agent. The acidic and neutral copolymers can be dissolved in the oral composition and the oral composition can form a film on a surface when contacted with an aqueous solution.Type: ApplicationFiled: September 10, 2014Publication date: August 4, 2016Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Yizhong Wang, Joel D. Oxman, Paul R. Klaiber, Jie J. Liu, Joanne A. Fitch, Tiffany T. Ton, Reinhold Hecht
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Patent number: 8557893Abstract: Substituted saccharide compounds, dental compositions comprising substituted saccharide compounds, and methods of using dental compositions are described. In one embodiment, the substituted saccharide amide compound comprises a hydrophobic group and at least one free-radically polymerizable group with the proviso that the hydrophobic group is not bonded to the ethylenically unsaturated carbon atom of the free-radically polymerizable group. The hydrophobic group is typically bonded to a nitrogen atom of a saccharide amine residue or a carbonyl moiety of saccharide amide residue.Type: GrantFiled: August 19, 2011Date of Patent: October 15, 2013Assignee: 3M Innovative Properties CompanyInventors: Jie Yang, Sumita B. Mitra, Yi He, Brian A. Shukla, Naimul Karim, Afshin Falsafi, Richard B. Ross, Paul R. Klaiber, George W. Griesgraber
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Publication number: 20130164709Abstract: Substituted saccharide compounds, dental compositions comprising substituted saccharide compounds, and methods of using dental compositions are described. In one embodiment, the substituted saccharide amide compound comprises a hydrophobic group and at least one free-radically polymerizable group with the proviso that the hydrophobic group is not bonded to the ethylenically unsaturated carbon atom of the free-radically polymerizable group. The hydrophobic group is typically bonded to a nitrogen atom of a saccharide amine residue or a carbonyl moiety of saccharide amide residue.Type: ApplicationFiled: August 19, 2011Publication date: June 27, 2013Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Jie Yang, Sumita B. Mitra, Yi He, Brian A. Shukla, Naimul Karim, Afshin Falsafi, Richard B. Ross, Paul R. Klaiber, George W. Griesgraber