Abstract: The present invention provides an isolated animal cell comprising an exogenous nucleic acid encoding a mutated phytase, wherein the cell produces phytase and secretes the phytase from the cell. The present invention also provides an animal having a phenotype not naturally occurring, characterized by secretion of phytase into the lumen of the gastrointestinal tract of the animal, the phenotype being conferred by a transgene contained in the cells of the animal, the transgene comprising a nucleic acid sequence encoding phytase and methods of making said animal.

Abstract: The present invention provides an isolated animal cell comprising an exogenous nucleic acid encoding a mutated phytase, wherein the cell produces phytase and secretes the phytase from the cell. The present invention also provides an animal having a phenotype not naturally occurring, characterized by secretion of phytase into the lumen of the gastrointestinal tract of the animal, the phenotype being conferred by a transgene contained in the cells of the animal, the transgene comprising a nucleic acid sequence encoding phytase and methods of making said animal.

Abstract: The present invention relates to an isolated protein or polypeptide selectively expressed in chondrocytes in lower proliferative or upper hypertrophic zones of long bone and embryonic vertebrae growth plates as well as to antibodies, fragments, and probes recognizing these proteins or polypeptides. The proteins or polypeptides can be used for treating non-union bone defects. The antibodies, binding portions thereof, and probes can be used to inhibit arthritic progression of articular chondrocytes. The antibodies, binding portions thereof, and probes can also be used to identify the occurrence of chondrocytes proliferation or hypertrophy. The encoding DNA molecule, either alone in isolated form or in an expression system or a host cell, is also disclosed.

Abstract: A system for designing an intercommunication network among a plurality of devices. The system includes a device for storing rules to meet design requirements and a mechanism connected to the device for storing rules in order to revise the rules dynamically. Also provided is a device for storing data and a mechanism connected to the device for storing data in order to revise the data. A requestor has the ability to access all rules and to revise a portion of the data. Moreover, a designer has the ability to access all rules and to revise another portion of the data, which portion has at least one subportion that cannot be revised by the requestor.

Abstract: A system for designing an intercommunication network among a plurality of devices. The system includes a device for storing rules to meet design requirements and a mechanism connected to the device for storing rules in order to revise the rules dynamically. Also provided is a device for storing data and a mechanism connected to the device for storing data in order to revise the data. A requestor has the ability to access all rules and to revise a portion of the data. Moreover, a designer has the ability to access all rules and to revise another portion of the data, which portion has at least one subportion that cannot be revised by the requestor.