Abstract: There are provided systems and methods for using fuel-rich partial oxidation to produce an end product from waste gases, such as flare gas. In an embodiment, the system and method use air-breathing piston engines and turbine engines for the fuel-rich partial oxidation of the flare gas to form synthesis gas, and reactors to convert the synthesis gas into the end product. In an embodiment the end product is methanol.

Abstract: Disclosed are devices, systems, and methods of a wearable compression control system for actively controlling an applied pressure against an extremity to restrict blood flow along the extremity of a user performing an exercise or undergoing a therapy. In some embodiments, the system can include an inflatable band that extends circumferentially around the extremity. The inflatable band can include a bladder having an expandable inner volume for receiving fluid to cause the inflatable band to increase in thickness and increase an applied pressure against the extremity. The system can further include a controller that releasably couples to the inflatable band and includes a processor having a programmed pressure range. The processor can be configured to actively maintain the applied pressure within the programmed pressure range throughout the user performing the exercise or the user undergoing the therapy.

Abstract: The present disclosure is directed to a method of operating a chromatography column. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is determined based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. The height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: A method of operating a chromatography column is described. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is calculated based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. A height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: The present disclosure is directed to a method of operating a chromatography column in methods of manufacture for producing anti-IL-12/IL-23p40 antibodies, e.g., the anti-IL-12/IL-23p40 antibody STELARA® (ustekinumab), specific pharmaceutical compositions of the antibodies, and antigen binding fragments thereof. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is determined based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. The height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: A method of operating a chromatography column is described for use in methods of manufacture for producing anti-IL-12/IL-23p40 antibodies, e.g., the anti-IL-12/IL-23p40 antibody STELARA® (ustekinumab). This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is calculated based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. A height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: A method of operating a chromatography column is described for use in methods of manufacture for producing anti-TNF antibodies, e.g., the anti-TNF? antibody SIMPONI® (golimumab). This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is calculated based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. A height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: A method of operating a chromatography column is described. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is calculated based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. A height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: A method of operating a chromatography column is described for use in methods of manufacture for producing anti-IL-12/IL-23p40 antibodies, e.g., the anti-IL-12/IL-23p40 antibody STELARA® (ustekinumab). This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is calculated based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. A height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value.

Abstract: The invention builds a natural-language query by associating a auto-complete menu system with a domain-specific concept model, generating a command displayed in a list of proper commands, in a auto-complete fashion to the user (the list of proper commands comprising all elements of a set of proper commands), detecting a command choice of the user, and displaying the command choice in the entry area upon determining that the command choice is a proper command, and generating a target concept in a similar manner. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).

Abstract: The invention utilizes a known syntax and concept model to enable a user to make a reliable and accurate database query with words that more closely resemble the user's natural language and less like a structured database query. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).

Abstract: The invention compares a user-generated inquiry to a known data source in order to present a user with a choice of valid natural language inquiries. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims.

Abstract: The invention defines a domain specific concept model that is flexible, intuitive, and which easily integrates into disparate, but similarly architected, domain-specific databases. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. 37 CFR 1.72(b).

Abstract: Disclosed are catalysts comprising copper chromite, palladium and lanthanum having hydrogenation activity. The combination of copper chromite with palladium and lanthanum enhances catalyst activity more than the presence of either palladium alone or palladium in combination with alkali or alkaline earth metals. The catalysts are useful for the preparation of methanol from carbon monoxide and hydrogen and for the hydrogenation of carbonyl compounds such as, for example, aldehydes, ketones, and esters, to their corresponding alcohols. The catalysts may be used for the preparation of cyclohexanedimethanols from dialkyl cyclohexanedicarboxylates or of ethylene glycol from alkyl glycolates.

Abstract: Disclosed are catalysts comprising copper chromite, ruthenium and at least one promoter selected from alkali metals, alkaline earth metals, rare earth elements having hydrogenation activity. The combination of copper chromite with ruthenium and the alkali, alkaline earth, and/or rare earth elements enhances catalyst activity more than the addition of either type of promoter alone. The catalysts are useful for the preparation of methanol from carbon monoxide and hydrogen and for the hydrogenation of carbonyl compounds such as, for example, aldehydes, ketones, and esters, to their corresponding alcohols. The catalysts may be used for the preparation of cyclohexanedimethanols from dialkyl cyclohexanedicarboxylates or of ethylene glycol from alkyl glycolates.

Abstract: Disclosed are catalysts comprising copper chromite, palladium and lanthanum having hydrogenation activity. The combination of copper chromite with palladium and lanthanum enhances catalyst activity more than the presence of either palladium alone or palladium in combination with alkali or alkaline earth metals. The catalysts are useful for the preparation of methanol from carbon monoxide and hydrogen and for the hydrogenation of carbonyl compounds such as, for example, aldehydes, ketones, and esters, to their corresponding alcohols. The catalysts may be used for the preparation of cyclohexanedimethanols from dialkyl cyclohexanedicarboxylates or of ethylene glycol from alkyl glycolates.

Abstract: A retainer clip includes a ratchet plate and a cooperating pawl for anchoring a sink to a countertop with a press-in, above-counter installation. The ratchet plate has a plurality of detents and is affixed to an edge of a cutout in the countertop. The pawl includes a spring element mountable to the sink and has at least one upwardly angled, resilient tab which successively engages the ratchet plate detents with a one-way action as the sink moves downwardly in the cutout. When the sink is fully inserted, the tab seats upwardly in a detent of the ratchet plate. In an embodiment, the pawl includes multiple tabs having slightly different lengths to provide an installation tolerance that is less than an incremental distance between ratchet plate detents.

Abstract: A retainer clip includes a ratchet plate and a cooperating pawl for anchoring a sink to a countertop with a press-in, above-counter installation. The ratchet plate has a plurality of detents and is affixed to an edge of a cutout in the countertop. The pawl includes a spring element mountable to the sink and has at least one upwardly angled, resilient tab which successively engages the ratchet plate detents with a one-way action as the sink moves downwardly in the cutout. When the sink is fully inserted, the tab seats upwardly in a detent of the ratchet plate. In an embodiment, the pawl includes multiple tabs having slightly different lengths to provide an installation tolerance that is less than an incremental distance between ratchet plate detents.

Abstract: A sink mounting device includes a weld bracket, a movable clip member and a hanger assembly used to movably couple the clip member to the weld bracket. The weld bracket is secured to a side portion of a sink bowl and the movable clip is used to engage an overhanging portion of the underside of the countertop. The clip includes a base having an axially positioned through-opening, an elongated arm member which extends longitudinally in a direction axially from the base, a projecting finger, which extends laterally from the end of the arm remote from the base, and includes a locating flange which, when the sink mounting device is operated, engages the hanger assembly, weld bracket and/or sink bowl at a limit position to prevent further rotation of the movable arm about the axis.

Abstract: A portable unit comprising a tiltable accelerometer is mounted on a vehicle which is allowed to coast on a plane and a reading is taken to provide an indication of vehicle rolling resistance without regard to terrain, slope, vehicle weight or speed. By proper precalibration of the accelerometer, it is possible to obtain the coefficient of friction directly from the accelerometer reading. Other values which may be directly obtained from the output of the accelerometer when it is properly recalibrated include accelerating rate and braking rate of a vehicle and grade of terrain.