Abstract: A bioreactor comprising a housing defining a perfusion chamber, the housing including at least one port, wherein the at least one port is coupled to the housing, and a sample holder positioned within the perfusion chamber. A bioreactor and spheroid-based biofabrication method for making perfusible tissue constructs and perfusing them.

Abstract: The invention concerns pharmaceutical compositions containing a hydrogen sulphate salt of 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and solvates, crystalline forms and amorphous forms thereof, to the use of said compositions as a medicament, and to processes for the preparation of said compositions.

Abstract: A system and method enabling the automated installation and configuration of satellite system premises device. The system and method utilize stored information indicative of the types of viable interfaces that a premises device should be adapted to mate with, to intelligently recognize a particular subset of satellite system signals, and then responsively configure and install a premises device.

Abstract: An access control system for controlling access to restricted physical areas, the access control system comprising: a first access control apparatus for controlling access to a first restricted physical area, the first access control apparatus comprising a first data store storing a first list of access tokens by which the first restricted physical area can be accessed; and a second access control apparatus for controlling access to a second restricted physical area, the second access control apparatus comprising a second data store storing a second list of access tokens by which the second restricted physical area can be accessed and a third list of access tokens by which it is desired that the first restricted physical area can be accessed; the second access control apparatus being responsive to an indication from the first access control apparatus of a location of a third data store to write the third list to the third data store; and the first access control apparatus being operative to: (i) receive the t

Abstract: Provided is an axial flux motor including a rotor having a wound ribbon core, the wound ribbon core including a metal amorphous nanocomposite material. The axial flux motor further includes a stator assembly spaced apart from the rotor along a rotation axis of the rotor. The stator assembly includes a body including a metal amorphous nanocomposite material and a plurality of permanent magnets substantially free of rare-earth materials. The plurality of permanent magnets is arranged on the body of the stator assembly.

Abstract: A flag system removably attaches to a rearview mirror of a vehicle. The system uses a pair of clips that each hook, via a hook portion, to a rearward facing edge of the mirror housing, one clip hooked to the upper edge of the housing, the other clip hooked to the lower edge of the housing. A flag extends upwardly from the upper clip. A strap connects the two clips and passes along the forward-facing outer surface of the mirror housing. The strap is pulled taut and secured in the taut position, thereby securing the flag system to the mirror housing. The flag may be secured to a post which is attached to the upper clip. Strap sizing can be achieved using a pair of cooperating hook and loop sections, one section at an end of the strap, the other section located medially along the strap.

Abstract: A composite, zone-coated, dual-use ammonia (AMOX) and nitric oxide oxidation catalyst (12) comprises: a substrate (5) having a total length L and a longitudinal axis and having a substrate surface extending axially between a first substrate end (I) and a second substrate end (O); two or more catalyst washcoat zones (1; 2) comprised of a first catalyst washcoat layer (9) comprising a refractory metal oxide support material and one or more platinum group metal components supported thereon and a second catalyst washcoat layer (11) different from the first catalyst washcoat layer (9) and comprising a refractory metal oxide support material and one or more platinum group metal components supported thereon, which two or more catalyst washcoat zones (1; 2) being arranged axially in series on and along the substrate surface, wherein a first catalyst washcoat zone (1) having a length L1, wherein L1<L, is defined at one end by the first substrate end (I) and at a second end (13) by a first end (15) of a second catal

Abstract: The present disclosure relates to adapter assemblies for use with and to electrically and mechanically interconnect electromechanical surgical devices and surgical reloads, and to surgical systems including handheld electromechanical surgical devices and adapter assemblies for connecting surgical reloads to the handheld electromechanical surgical devices.

Abstract: A near-field probe (and associated method) compatible with near-infrared electromagnetic radiation and high temperature applications above 300° C. (or 500° C. in some applications) includes an optical waveguide and a photonic thermal emitting structure comprising a near-field thermally emissive material coupled to or part of the optical waveguide. The photonic thermal emitting structure is structured and configured to emit near-field energy responsive to at least one environmental parameter of interest, and the near-field probe is structured and configured to enable extraction of the near-field energy to a far-field by coupling the near-field energy into one or more guided modes of the optical waveguide.

Abstract: An electrical system for a drug delivery device is proposed, the electrical system comprising an electrical liquid sensitive unit, wherein the electrical liquid sensitive unit comprises at least one liquid sensing arrangement, wherein the electrical liquid sensitive unit is configured to react to the exposure of the liquid sensing arrangement to liquid, and wherein the electrical system is configured to change its state from a normal state to an error state in response to the exposure of the at least one liquid sensing arrangement to liquid.

Abstract: The present disclosure relates to an encoder ring for a dose recording system of a drug delivery device. The encoder ring includes a support ring having a substantially circular configuration and includes a proximal end face and a distal end face. The encoder ring further includes a series of flag segments rigidly connected to each other via the support ring, wherein each flag segment has a substantially rectangular outer surface extending in a curved plane, and wherein at least one flag segment of the series of flag segments includes one or more of a retention clip and a positioning pin.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: Electronic system, user interface member, drug delivery device and method for detecting whether a drug delivery device is, or was, exposed to fluid In at least one embodiment, the electronic system is configured to compare measurements taken with a measurement (21) unit with a reference and to determine, based on the result of the comparison, an exposure of the drug delivery device to fluid. The measurements are suitable to provide information about the drug delivery device.

Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.

Abstract: The present disclosure is generally directed to an attachment mechanism suitable for attaching a module to an object, e.g. to a portion of a drug delivery device. Further, the disclosure is directed to an electronic system, e.g. an electronic add-on module, which is configured to be, e.g. releasably, attached to a drug delivery device as well as an assembly including the electronic add-on module as well as the drug delivery device. The attachment mechanism may include at least one attachment member with a longitudinal axis, an adhesive distal end surface and an opposite adhesive proximal end surface.

Abstract: An implantable neuromodulation system can include an electrode configured to be disposed at or near a first branch of a hypoglossal nerve of a patient and configured to provide a first electrostimulation therapy to treat a sleep disorder or breathing disorder of a patient. The system can include a sensor configured to provide a sensor signal that includes information about a patient response to the first electrostimulation therapy, information about a patient respiration, or information about one or more other physiologic status indicators for the patient. The sensor signal information can be used to quantify a progression of a breathing disorder for the patient.

Abstract: A cleaning roller is mountable to a cleaning robot. The cleaning roller includes a sheath comprising a shell, an outer diameter of the shell tapering from a first end portion of the sheath and a second end portion of the sheath toward a center of the roller. The cleaning roller further includes a core including a central portion interlocked with the sheath to rotationally couple the core to the sheath and inhibit relative translation of the sheath and the core along an axis of rotation. An inner surface of the sheath and an outer surface of the core define an air gap therebetween, the air gap extending from the central portion of the core longitudinally along the axis of rotation toward the first end portion or the second end portion.

Abstract: The invention concerns pharmaceutical compositions containing a hydrogen sulphate salt of 6-(4-bromo-2-chloro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide and solvates, crystalline forms and amorphous forms thereof, to the use of said compositions as a medicament; and to processes for the preparation of said compositions.

Abstract: A nameserver receives a request to access a webpage from a client device. The nameserver generates a blockchain query based on the request for querying a domain registrar blockchain storing domain name registration data in smart contracts. The nameserver sends the first blockchain query to the domain registrar blockchain. In response to receiving a nameserver identifier from the domain registrar blockchain, the nameserver retrieves a DNS record for the webpage using the received nameserver identifier. The nameserver then provides information from the retrieved DNS record to the client device to allow the client device to access the webpage.

Abstract: A system for controlling a steam cracking furnace may include a controller configured to control an electric heater to pre-heat a combustion air feed to a radiation section of the cracking furnace, and one or more sensors configured to sense properties of a recovered pure hydrogen stream fed to the radiation section of the cracking furnace as fuel. The controller can be configured to receive the sensed properties from the one or more sensors and control the electric heater based on the one or more sensed properties.