Patents by Inventor Paul Richard Giles

Paul Richard Giles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Probes for imaging huntingtin protein
    Patent number: 12258355
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: March 25, 2025
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Samuel Coe, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Jonathan Bard, Elise Lucienne Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • Probes for imaging huntingtin protein
    Patent number: 11059836
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: July 13, 2021
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Samuel Coe, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Jonathan Bard, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • Probes for imaging huntingtin protein
    Patent number: 10907197
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: February 2, 2021
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Derek Alexander Weddell, Daryl Simon Walter, Paul Richard Giles, Ian James Wigginton, Malcolm George Taylor, Sébastien René Gabriel Galan, Peter David Johnson, Thomas Martin Krülle, Inaki Morao, Daniel Clark-Frew
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20200102328
    Abstract: Provided are imaging agents comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 2, 2019
    Publication date: April 2, 2020
    Inventors: Celia Dominguez, Samuel Coe, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Jonathan Bard, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • Probes for imaging huntingtin protein
    Patent number: 10479802
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: November 19, 2019
    Assignee: CHDI Foundation, Inc.
    Inventors: Celia Dominguez, Samuel Coe, Jonathan Bard, Peter David Johnson, Michael Edward Prime, Christopher John Brown, Sébastien René Gabriel Galan, Paul Richard Giles, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, John Wityak, Alex Kiselyov, Sarah Hayes
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20170292150
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 28, 2015
    Publication date: October 12, 2017
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Christopher John Brown, Michael Edward Prime, Derek Alexander Weddell, Daryl Simon Walter, Paul Richard Giles, Ian James Wigginton, Malcolm George Taylor, Sébastien René Gabriel Galan, Peter David Johnson, Thomas Martin Krülle, Inaki Morao, Daniel Clark-Frew
  • PROBES FOR IMAGING HUNTINGTIN PROTEIN
    Publication number: 20170283436
    Abstract: Provided are imaging agents comprising a compound of Formula (I), or a pharmaceutically acceptable salt thereof, and methods of their use.
    Type: Application
    Filed: August 28, 2015
    Publication date: October 5, 2017
    Inventors: Celia Dominguez, John Wityak, Jonathan Bard, Alex Kiselyov, Christopher John Brown, Sébastien René Gabriel Galan, Michael Edward Prime, Paul Richard Giles, Elise Luciennen Paulette Gadouleau, Thomas Martin Krülle, Daniel Clark-Frew, Peter David Johnson, Samuel Coe, Sarah Hayes
  • Thieno-and furopyrimidine derivatives as A2A-receptor antagonists
    Patent number: 6787541
    Abstract: Compounds of formula (I): wherein X is S. Compounds can be used for treating a disorder in which the blocking of purine receptors is beneficial.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: September 7, 2004
    Assignee: Vernalis Research Limited
    Inventors: Roger John Gillespie, Joanne Lerpiniere, Paul Richard Giles, Claire Elizabeth Dawson, David Bebbington
  • 4-quinolinemethanol derivatives as purine receptor antagonists (II)
    Patent number: 6608085
    Abstract: Use of a compound of formula (I) as defined herein, or a pharmaceutically acceptable salt or prodrug thereof, in the manufacture of a medicament for the treatment or prevention of a disorder in which the blocking of purine receptors, particularly adenosine receptors and more particularly A2a receptors, may be beneficial, such as a movement disorder, for example, Parkinson's Disease or progressive supemuclear palsy, Huntingtons disease, multiple system atrophy, corticobasal degeneration, Wilsons disease, Hallerrorder-Spatz disease, progressive pallidal atrophy, Dopa-responsive dystonia-Parkinsonism, spasticity, Alzheimer's disease or other disorders of the basal ganglia which result in dyskinesias.
    Type: Grant
    Filed: May 9, 2001
    Date of Patent: August 19, 2003
    Assignee: Vernalis Research Limited
    Inventors: Roger John Gillespie, Joanne Lerpiniere, Paul Richard Giles, David Reginald Adams, Lars Jacob Stray Knutsen, Ian Anthony Cliffe
  • Preparation of aldehydes or ketones from alcohols
    Patent number: 5912388
    Abstract: A process for preparing an aldehyde or ketone comprising reacting a primary or secondary alcohol with oxygen in the presence of a base, a catalytic amount of a copper salt and a suitable lignad under anhydrous conditions.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: June 15, 1999
    Assignee: Zeneca Limited
    Inventors: Christopher John Urch, Istvan Ettienne Marko, Masao Tuskazaki, Paul Richard Giles, Stephen Martin Brown