Patents by Inventor Paul Richard Moody

Paul Richard Moody has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230084931
    Abstract: Methods of characterizing an analyte using a nanopore. One aspect features methods for characterizing a double-stranded polynucleotide using a nanopore, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.
    Type: Application
    Filed: August 3, 2022
    Publication date: March 16, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: James Anthony Clarke, James White, Richard Muscat, Jessica Mary May Knott, Ramiz Iqbal Nathani, Andrew John Heron, Mark John Bruce, Lakmal Jayasinghe, Domenico Caprotti, David Jackson Stoddart, Rebecca Victoria Bowen, Christopher James Wright, Paul Richard Moody
  • Publication number: 20230041418
    Abstract: Provided herein is a method of concentrating a tethering complex in a region of an amphiphilic layer, such as a lipid membrane. Also provided herein are methods of assembling a tethering complex; methods of concentrating an analyte in the region of a detector; amphiphilic layers; and arrays and devices for use in the disclosed methods.
    Type: Application
    Filed: December 3, 2020
    Publication date: February 9, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Clive Gavin Brown, Andrew John Heron, James Anthony Clarke, Paul Richard Moody, Aaron Luke Acton, Jason Robert Hyde
  • Patent number: 11466317
    Abstract: Methods of characterizing an analyte using a nanopore. One aspect features methods for characterizing a double-stranded polynucleotide using a nanopore, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: October 11, 2022
    Assignee: Oxford Nanopore Technologies PLC
    Inventors: James Clarke, James White, Richard Muscat, Jessica Mary May Knott, Ramiz Iqbal Nathani, Andrew John Heron, Mark John Bruce, Lakmal Nishantha Jayasinghe, Domenico Caprotti, David Jackson Stoddart, Rebecca Victoria Bowen, Christopher James Wright, Paul Richard Moody
  • Publication number: 20210363577
    Abstract: Methods of characterizing an analyte using a detector such as a nanopore and an enzyme are provided. One aspect features methods for characterizing a double-stranded polynucleotide using a detector, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.
    Type: Application
    Filed: June 6, 2019
    Publication date: November 25, 2021
    Applicant: Oxford Nanopore Technologies Limited
    Inventors: James Anthony Clarke, James White, Richard Muscat, Jessica Mary May Johnson, Ramiz Iqbal Nathani, Andrew John Heron, Mark John Bruce, Lakmal Nishantha Jayasinghe, Domenico Caprotti, David Jackson Stoddart, Rebecca Victoria Bowen, Christopher James Wright, Paul Richard Moody
  • Publication number: 20190352709
    Abstract: Methods of characterizing an analyte using a nanopore. One aspect features methods for characterizing a double-stranded polynucleotide using a nanopore, e.g., without using a hairpin connecting a template and a complement of the double-stranded polynucleotide. Another aspect features methods for characterizing an analyte using a tag-modified nanopore with increased sensitivity and/or higher throughput. Compositions and systems including, e.g., adaptors for attachment to double-stranded polynucleotides and tag-modified nanopores, which can be used in the methods are also provided.
    Type: Application
    Filed: November 29, 2017
    Publication date: November 21, 2019
    Applicant: Oxford Nanopore Technologies Limited
    Inventors: James Clarke, James White, Richard Muscat, Jessica Mary May Knott, Ramiz Iqbal Nathani, Andrew John Heron, Mark John Bruce, Lakmal Nishantha Jayasinghe, Domenico Caprotti, David Jackson Stoddart, Rebecca Victoria Bowen, Christopher James Wright, Paul Richard Moody