Abstract: A malaria vaccine composition is disclosed herein that uses liver-stage parasite exported proteins as the target of a protective immune response instead of sporozoite proteins. Also disclosed is a recombinant viral particle that comprises a fusion protein disclosed herein, wherein the malaria antigen is displayed within the viral particle. Also disclosed is an isolated polynucleotide that comprises a nucleic acid sequence encoding a fusion protein disclosed herein operably linked to an expression control sequence. Also disclosed is a recombinant herpes simplex virus (HSV) genome comprising a modified VP26 gene encoding a fusion protein disclosed herein. Also disclosed is a vaccine composition that comprises a recombinant viral particle disclosed herein in a pharmaceutically acceptable excipient. In some cases, the composition further comprises an adjuvant.

Abstract: A feedback loop for the assessment of a user interface of a communications network is based on feature units for analysis and comparison. These units are subset collections that are grouped together to perform a particular task or function. When, these units can be objectively and quantitatively assessed, and compared among various user interfaces. The quantification, assessment, market testing and comparison informs the feedback loop to reveal ways in which a user interface can be improved so as to benefit a company's ability to effectively communicate with its customers. A Constant Sum Scale question is used to support the comparison among user interface features, and is also applicable in a wide variety of contexts.