Patents by Inventor Paul Robel

Paul Robel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating a degenerative disease of the nervous system using 3-methoxy-pregnenolone or derivatives thereof
    Patent number: 10561671
    Abstract: The present invention relates to a method of enhancing retention of recognition memory and/or recovering recognition memory deficits using 3?-methoxy-pregna-5-ene-20-one.
    Type: Grant
    Filed: November 24, 2015
    Date of Patent: February 18, 2020
    Assignee: MAPREG
    Inventors: Etienne-Emile Baulieu, Esther Fellous, Paul Robel
  • METHOD FOR TREATING A DEGENERATIVE DISEASE OF THE NERVOUS SYSTEM USING 3-METHOXY-PREGNENOLONE OR DERIVATIVES THEREOF
    Publication number: 20160166586
    Abstract: The present invention relates to a method for the treatment of a degenerative disease of the nervous system in a patient, comprising administering to said patient an effective quantity of 3?-methoxy-pregna-5-ene-20-one (3?-methoxy-PREG) or derivatives thereof.
    Type: Application
    Filed: November 24, 2015
    Publication date: June 16, 2016
    Applicant: MAPREG
    Inventors: Etienne-Emile BAULIEU, Esther FELLOUS, Paul ROBEL
  • Use of 3-methoxy-pregnenolone for the preparation of a drug for treating a traumatic brain injury
    Patent number: 9339508
    Abstract: A method for the treatment of a traumatic brain lesion comprises administering to the patient an effective quantity of 3?-methoxy-pregna-5-ene-20-one (3?-methoxy-PREG).
    Type: Grant
    Filed: November 1, 2012
    Date of Patent: May 17, 2016
    Assignee: MAPREG
    Inventors: Etienne-Emile Baulieu, Esther Fellous, Paul Robel
  • THE USE OF 3-METHOXY-PREGNENOLONE FOR HTE PREPARATION OF A DRUG FOR TREATING A TRAUMATIC BRAIN INURY
    Publication number: 20140228336
    Abstract: A method for the treatment of a traumatic brain lesion comprises administering to the patient an effective quantity of 3?-methoxy-pregna-5-ene-20-one (3?-methoxy-PREG).
    Type: Application
    Filed: November 1, 2012
    Publication date: August 14, 2014
    Applicant: MAPREG
    Inventors: Etienne-Emile BAULIEU, Esther FELLOUS, Paul ROBEL
  • THE USE OF 3-METHOXY-PREGNENOLONE FOR THE PREPARATION OF A DRUG FOR TREATING A TRAUMATIC BRAIN INJURY
    Publication number: 20140045807
    Abstract: A method for the treatment of a traumatic brain lesion comprises administering to the patient an effective quantity of 3?-methoxy-pregna-5-ene-20-one (3?-methoxy-PREG).
    Type: Application
    Filed: November 1, 2012
    Publication date: February 13, 2014
    Inventors: Etienne-Emile BAULIEU, Ester Esther FELLOUS, Paul ROBEL, Massimiliano BIANCHI
  • USE OF 3-METHOXY-PREGNENOLONE FOR THE PREPARATION OF A DRUG FOR TREATING DEPRESSIVE DISORDERS AND LONG-TERM NEUROLOGICAL DISEASES
    Publication number: 20130244991
    Abstract: A method for the treatment of a traumatic brain lesion comprises administering to the patient an effective quantity of 3?-methoxy-pregna-5-ene-20-one (3?-methoxy-PREG).
    Type: Application
    Filed: November 1, 2012
    Publication date: September 19, 2013
    Applicant: MAPREG
    Inventors: Etienne-Emile BAULIEU, Ester FELLOUS, Paul ROBEL, Massimiliano BIANCHI
  • Use of 3-methoxy-pregnenolone for the preparation of a drug for treating depressive disorders and long-term neurological diseases
    Patent number: 8334278
    Abstract: The invention relates to the therapeutic use of pregnenolone derivatives for treating depressive disorders and long-term neurological diseases.
    Type: Grant
    Filed: September 26, 2008
    Date of Patent: December 18, 2012
    Assignee: Mapreg
    Inventors: Etienne-Emile Baulieu, Ester Fellous, Paul Robel, Massimiliano Bianchi
  • Use of 3-methoxy-pregnenolone in the production of a medicament for treating neurodegenerative diseases
    Patent number: 8034798
    Abstract: The invention relates to a novel use of derivatives of neurosteroids, particularly pregnenolone, for the treatment of acute or chronic lesions of the nervous system, especially certain neurodegenerative diseases, related in particular to the ability thereof to stabilize and/or increase the polymerization of neuronal microtubules.
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: October 11, 2011
    Assignee: MAPREG
    Inventors: Etienne-Emile Baulieu, Esther Fellous, Paul Robel
  • Use of 3-methoxy-pregnenolone for the preparation of a drug for treating depressive disorders and long-term neurological diseases
    Publication number: 20090143347
    Abstract: The invention relates to the therapeutic use of pregnenolone derivatives for treating depressive disorders and long-term neurological diseases.
    Type: Application
    Filed: September 26, 2008
    Publication date: June 4, 2009
    Inventors: Etienne-Emile Baulieu, Ester Fellous, Paul Robel, Massimiliano Bianchi
  • Use of 3-methoxy-pregnenolone in the production of a medicament for treating neurodegenerative diseases
    Publication number: 20060199790
    Abstract: The invention relates to a novel use of derivatives of neurosteroids, particularly pregnenolone, for the treatment of acute or chronic lesions of the nervous system, especially certain neurodegenerative diseases, related in particular to the ability thereof to stabilize and/or increase the polymerization of neuronal microtubules.
    Type: Application
    Filed: January 16, 2004
    Publication date: September 7, 2006
    Inventors: Etienne-Emile Baulieu, Esther Fellous, Paul Robel
  • Compounds capable of binding to proteins constituting or associated with cytoskeletal elements, and their applications for the manufacture of medicaments
    Publication number: 20050197322
    Abstract: The invention concerns the use of steroids and non-toxic compounds, capable of crossing the blood brain barrier characterized in that they are capable of binding the same site as pregnenolone on proteins constituting or associated with elements of the cytoskeleton and of displacing the MAP2-bound pregnenolone, and of influencing the assembling and stabilization of microtubules. The invention is particularly useful for treating the nervous system, for fighting against ageing of cells containing MAP5, and for treating cancers.
    Type: Application
    Filed: March 28, 2005
    Publication date: September 8, 2005
    Inventors: Etienne-Emile Baulieu, Paul Robel, Esther Fellous, Koichi Murakami
  • Compounds capable of binding with the cytoskeleton
    Publication number: 20030125311
    Abstract: The invention concerns the use of steroids and non-toxic compounds, capable of crossing the blood brain barrier characterised in that they are capable of binding the same site as pregnenolone on proteins constituting or associated with elements of the cytoskeleton and of displacing the MAP-bound pregnenolone, and of influencing the assembling and stabilisation of microtubules The invention is particularly useful for treating the nervous system, for fighting against ageing of cells containing MAPs, and for treating cancers.
    Type: Application
    Filed: September 17, 2002
    Publication date: July 3, 2003
    Inventors: Etienne-Emile Baulieu, Paul Robel, Esther Pellous, Kokhi Murakami