Patents by Inventor Paul Roche

Paul Roche has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11413300
    Abstract: Methods are disclosed for the reduction or elimination of bacterial biofilms on biological and non-biological surfaces, as methods for the treatment of wounds, skin lesions, mucous membrane lesions, and other biological surfaces infected or contaminated with bacterial biofilms using compositions comprising a synergistic combination of thermolysin and at least one aminoglycoside antibacterial agent.
    Type: Grant
    Filed: January 26, 2018
    Date of Patent: August 16, 2022
    Assignee: SMITH & NEPHEW, INC.
    Inventors: Aleksa Jovanovic, Lei Shi, Eric Roche, Paul Renick
  • Patent number: 10070910
    Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
    Type: Grant
    Filed: July 9, 2013
    Date of Patent: September 11, 2018
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Frank W. Ingle, Robert F. Bencini, Josef V. Koblish, Jonathan A. Wohlgemuth, Paul A. Roche
  • Publication number: 20170143419
    Abstract: An embodiment of a system for ablating tissue comprises an electrode configured for use to deliver RF power to ablate the tissue, and a heat flow sensor configured to provide a measurement of heat flow from the electrode to blood or irrigation fluid. According to some embodiments, the system further comprises an RF source configured to generate RF power connected to the electrode (PE) to ablate tissue, and a controller configured to control a level of RF power and a duration for an ablation procedure. The controller is programmed to implement a process to estimate RF power dissipated in tissue (PT), including calculating power loss due to convective heat flow (PCONV) from the tissue through the electrode to the blood or the irrigation fluid to cool the electrode, and calculating the RF power dissipated in tissue (PT) by subtracting PCONV from PE.
    Type: Application
    Filed: February 1, 2017
    Publication date: May 25, 2017
    Inventors: Frank Ingle, Paul A. Roche
  • Publication number: 20150327922
    Abstract: An ablation catheter system includes a tip assembly configured to provide ablation energy to tissue. The tip assembly includes an outer surface and a piezoelectric element is acoustically coupled to the outer surface of the tip assembly. The piezoelectric element is configured to cause the outer surface of the tip assembly to vibrate.
    Type: Application
    Filed: May 14, 2015
    Publication date: November 19, 2015
    Inventors: Shuja Dawood, Jennifer Leschkies, Anna Mandernach, Rebecca Tin, Venkata Vegesna, Paul A. Roche, Vikrant Singh Badwal, Noel Keane, Adrian Valdelomar, Priya Sundaramurthy
  • Patent number: 9119636
    Abstract: An electrosurgery system includes a catheter including one or more active electrodes adapted to be positioned adjacent biological tissue at an in vivo treatment site in a patient and to deliver electrical energy to the biological tissue. The electrosurgery system further includes a dispersive electrode assembly including a conductive element having a first end and a second end. The dispersive electrode assembly is configured to surround a waist of the patient such that a first surface of the conductive element is in contact with the waist and the first end of the conductive element is adjacent the second end of the conductive element.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: September 1, 2015
    Assignee: Boston Scientific Scimed Inc.
    Inventors: Venkata Vegesna, Paul A. Roche
  • Patent number: 9080551
    Abstract: An energy generation system works to convert wind created by aircraft exhaust into electrical power. The system uses a wind turbine including a plurality of blades extending from a shaft with a generator coupled to the shaft. The wind turbine is placed behind a runway to collect the wind from the engine of an aircraft, generating energy and converting the energy into electricity.
    Type: Grant
    Filed: February 4, 2013
    Date of Patent: July 14, 2015
    Inventors: Alexander Jay Yudkovitz, Sheran Ranchith Perera, Paul Roche Bartholomew, Samuel David Faggert, Michael Andrew Cwietniewicz
  • Publication number: 20150141978
    Abstract: Ablation devices and methods for determining a degree of contact between an electrode and a target tissue are disclosed. An example ablation device for treating body tissue may include a catheter having a proximal end region and a distal end region. An electrode may be disposed adjacent to the distal end region of the catheter. The device may also include a processing unit having a memory. The processing unit may be in electrical communication with the electrode. The processing unit may be capable of determining a degree of contact between the electrode and a target tissue.
    Type: Application
    Filed: November 19, 2014
    Publication date: May 21, 2015
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: RAJ SUBRAMANIAM, PAUL A. ROCHE
  • Patent number: 8702693
    Abstract: Methods and apparatus for supplying fluid during a tissue coagulation procedure.
    Type: Grant
    Filed: February 15, 2010
    Date of Patent: April 22, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Raj Subramaniam, Paul Roche
  • Publication number: 20130341932
    Abstract: An energy generation system works to convert wind created by aircraft exhaust into electrical power. The system uses a modified version of an Archimedes screw-shaped wind turbine placed behind a runway to collect the energy, currently wasted, from the aircraft and convert it to usable electricity.
    Type: Application
    Filed: February 4, 2013
    Publication date: December 26, 2013
    Inventors: Alexander Jay Yudkovitz, Sheran Ranchith Perera, Paul Roche Bartholomew, Samuel David Faggert, Michael Andrew Cwietniewicz
  • Publication number: 20130289550
    Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
    Type: Application
    Filed: July 9, 2013
    Publication date: October 31, 2013
    Inventors: FRANK W. INGLE, ROBERT F. BENCINI, JOSEF V. KOBLISH, JONATHAN A. WOHLGEMUTH, PAUL A. ROCHE
  • Patent number: 8480663
    Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: July 9, 2013
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Frank W. Ingle, Robert F. Bencini, Josef V. Koblish, Jonathan A. Wohlgemuth, Paul Roche
  • Publication number: 20120330304
    Abstract: An electrosurgery system includes a catheter including one or more active electrodes adapted to be positioned adjacent biological tissue at an in vivo treatment site in a patient and to deliver electrical energy to the biological tissue. The electrosurgery system further includes a dispersive electrode assembly including a conductive element having a first end and a second end. The dispersive electrode assembly is configured to surround a waist of the patient such that a first surface of the conductive element is in contact with the waist and the first end of the conductive element is adjacent the second end of the conductive element.
    Type: Application
    Filed: May 14, 2012
    Publication date: December 27, 2012
    Inventors: Venkata Vegesna, Paul A. Roche
  • Publication number: 20110022041
    Abstract: An embodiment of a system for ablating tissue comprises an electrode configured for use to deliver RF power to ablate the tissue, and a heat flow sensor configured to provide a measurement of heat flow from the electrode to blood or irrigation fluid. According to some embodiments, the system further comprises an RF source configured to generate RF power connected to the electrode (PE) to ablate tissue, and a controller configured to control a level of RF power and a duration for an ablation procedure. The controller is programmed to implement a process to estimate RF power dissipated in tissue (PT), including calculating power loss due to convective heat flow (PCONV) from the tissue through the electrode to the blood or the irrigation fluid to cool the electrode, and calculating the RF power dissipated in tissue (PT) by subtracting PCONV from PE.
    Type: Application
    Filed: July 13, 2010
    Publication date: January 27, 2011
    Inventors: Frank Ingle, Paul Roche
  • Publication number: 20100211070
    Abstract: Methods and apparatus for supplying fluid during a tissue coagulation procedure.
    Type: Application
    Filed: February 15, 2010
    Publication date: August 19, 2010
    Inventors: Raj Subramaniam, Paul Roche
  • Publication number: 20090287202
    Abstract: Apparatus and methods for performing cryogenic ablation of tissue and adjusting the size and/or location of a cryogenic cooling region. A cooling assembly may include tubes for dispensing and exhausting a coolant or refrigerant. One or both of the tubes may be moved, e.g., slidably adjusted, in order to adjust the location or size of a cryogenic ablation region. The cooling assembly may be integrated into cryogenic ablation devices including a cryogenic balloon device that includes an inner inflatable balloon and another balloon that is at least partially wrapped around the inner balloon and carries refrigerant for performing cryo-ablation. Electrodes permit electrical mapping of tissue before or after cryo-ablation to verify success of the procedure.
    Type: Application
    Filed: April 29, 2009
    Publication date: November 19, 2009
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Frank W. Ingle, Robert F. Bencini, Josef V. Koblish, Jonathan A. Wohlgemuth, Paul Roche
  • Publication number: 20070199913
    Abstract: A container closure having a closed position and an open position and including a molded portion, such as a threaded flat cap, having a molded three dimensional image, in particular a lithophane image, on at least one surface thereof, wherein the image is configured to be viewed with the container in the open position and the image is configured to be un-viewable with the container in the closed position. The flat cap may include a sealing member such as a clear liner engaging a support shoulder surrounding the image. The flat cap may further include tamper evident features for the cap.
    Type: Application
    Filed: March 12, 2007
    Publication date: August 30, 2007
    Applicant: ERIE COUNTY PLASTICS CORPORATION
    Inventors: Peter Kelley, Joseph Mendillo, Patrick Pigott, Martin Binder, Brett Niggel, Paul Roche, Robert Smith