Patents by Inventor Paul Rothstein

Paul Rothstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220331105
    Abstract: A delivery system for transcatheter implantation of a heart valve prosthesis. The delivery system includes an outer sheath component defining a lumen therethrough, an elongate tube having at least two flat wires longitudinally extending from a distal end thereof, and self-expanding first and second frames disposed in series within a distal portion of the outer sheath component and held in a compressed delivery configuration therein. The elongate tube and the at least two flat wires are slidably disposed within the lumen of the outer sheath component. In the compressed delivery configuration the at least two flat wires longitudinally extend along exterior portions of the first and second frames and are woven through adjacent ends of the first and second frames to releasably couple them to each other. Proximal retraction of the at least two flat wires from the first and second frames releases at least the first frame from the delivery system.
    Type: Application
    Filed: July 6, 2022
    Publication date: October 20, 2022
    Inventors: Paul ROTHSTEIN, James R. KEOGH
  • Patent number: 11413172
    Abstract: An anchor stent assembly to be used with a valve component includes a generally tubular frame having a first end and a second end, the frame defining a central passage and a central axis. A secondary passage is defined between n inner surface of the frame and an outer surface of an inner rib disposed closer to the central axis than the frame. An extension tube is disposed through the secondary passage. The extension tube includes an extension tube lumen having a first opening at a first end of the extension tube and a second opening at a second end of the extension tube.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: August 16, 2022
    Assignee: Medtronic, Inc.
    Inventors: Shishira Nagesh, Paul Rothstein
  • Patent number: 11413144
    Abstract: A delivery system for transcatheter implantation of a heart valve prosthesis. The delivery system includes an outer sheath component defining a lumen therethrough, an elongate tube having at least two flat wires longitudinally extending from a distal end thereof, and self-expanding first and second frames disposed in series within a distal portion of the outer sheath component and held in a compressed delivery configuration therein. The elongate tube and the at least two flat wires are slidably disposed within the lumen of the outer sheath component. In the compressed delivery configuration the at least two flat wires longitudinally extend along exterior portions of the first and second frames and are woven through adjacent ends of the first and second frames to releasably couple them to each other. Proximal retraction of the at least two flat wires from the first and second frames releases at least the first frame from the delivery system.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: August 16, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: Paul Rothstein, James R. Keogh
  • Patent number: 11219434
    Abstract: A method of surgical dissection of tissue with a dissector comprising: an elongate shaft comprising a proximal portion and a distal portion, wherein the distal portion comprises a plurality of segments that articulate with respect to one another and the plurality of segments includes a distal segment having a distal end; and a handle attached to the proximal portion of the shaft, wherein the handle comprises controls for articulating the plurality of segments of the distal portion of the shaft with respect to one another, comprising the steps of: positioning the distal end of the dissector in a body; advancing the distal end through the body to dissect tissue; and simultaneously articulating the plurality of segments with respect to one another. A method of surgical dissection of tissue and guiding a second device to a desired physiological location with a first device.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: January 11, 2022
    Assignee: Medtronic, Inc.
    Inventors: Mark Thompson, Darrin Dickerson, Brett S. Bowman, Christopher F. Kelly, William W. Malecki, David Francischelli, Mark Stewart, Thomas Daigle, Douglas Gubbin, David Kim, Paul Rothstein, Adam Podbelski, Christopher Plott, Benjamin K. Yaffe
  • Publication number: 20210346000
    Abstract: Medical devices for closing anatomical apertures, such as atrial or ventricular septal defects, are disclosed. The medical devices can include a plug body having a proximal end, a distal end, and a longitudinal axis. The plug body can include an exterior surface, an interior surface defining an interior lumen, and a seal which can be located within the interior lumen. The medical devices can also include at least one arm member extending through the plug body between the exterior surface and the interior surface of the plug body. In certain embodiments, the medical device can include a distal loop and a proximal loop extending through the plug body. In certain embodiments, the proximal loop can be smaller than the distal loop, such that a top end and a bottom end of the proximal loop can fit within a top end and a bottom end of the distal loop.
    Type: Application
    Filed: July 23, 2021
    Publication date: November 11, 2021
    Inventors: Paul ROTHSTEIN, Paul A. IAIZZO
  • Patent number: 11071533
    Abstract: Medical devices for closing anatomical apertures, such as atrial or ventricular septal defects, are disclosed. The medical devices can include a plug body having a proximal end, a distal end, and a longitudinal axis. The plug body can include an exterior surface, an interior surface defining an interior lumen, and a seal which can be located within the interior lumen. The medical devices can also include at least one arm member extending through the plug body between the exterior surface and the interior surface of the plug body. In certain embodiments, the medical device can include a distal loop and a proximal loop extending through the plug body. In certain embodiments, the proximal loop can be smaller than the distal loop, such that a top end and a bottom end of the proximal loop can fit within a top end and a bottom end of the distal loop.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: July 27, 2021
    Assignee: Medtronic, Inc.
    Inventors: Paul Rothstein, Paul A. Iaizzo
  • Publication number: 20210177593
    Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.
    Type: Application
    Filed: February 5, 2021
    Publication date: June 17, 2021
    Applicant: Medtronic, Inc.
    Inventors: Joel Racchini, Paul Rothstein, Jeffrey Sandstrom
  • Publication number: 20210085453
    Abstract: A transcatheter prosthesis includes a stent, a prosthetic valve component, and an anti-paravalvular leakage component. The anti-paravalvular leakage component is coupled to the stent and includes an inner skirt, an outer wrap, a cavity, an opening, and a one-way valve. The inner skirt is disposed on an inner surface of the stent and has an inflow end and a downstream end. The outer wrap is disposed around an outer surface of the stent and has an inflow end coupled to the inflow end of the inner skirt and a downstream end. The cavity is formed between an outer surface of the inner skirt and an inner surface of the outer wrap. An opening is disposed between the inner skirt and the outer wrap. The one-way valve includes a flap at the opening configured to open to allow blood flow into the cavity but prevent blood flow out of the cavity.
    Type: Application
    Filed: September 24, 2019
    Publication date: March 25, 2021
    Inventors: Cynthia Clague, Ana Menk, Tim Petersen, Paul Rothstein, Stephen Roller
  • Publication number: 20210077258
    Abstract: A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.
    Type: Application
    Filed: December 1, 2020
    Publication date: March 18, 2021
    Applicant: Medtronic Vascular Galway
    Inventors: Marian Creaven, Marc Anderson, Kate Corish, Declan Costello, Niall Duffy, Joshua Dwork, John Gallagher, Patrick Griffin, Gavin Kenny, Deirdre McGowan Smyth, John Milroy, Jason Quill, Herinaina Rabarimanantsoa Jamous, Paul Rothstein, Jeffrey Sandstrom, Edmond Sheahan, Frank White
  • Patent number: 10945840
    Abstract: A system for replacing a heart valve of a patient. The system includes a delivery device and a prosthetic heart valve. The system is configured to be transitionable between a loaded state, a partially deployed state and a deployed state. In the loaded state, the prosthetic heart valve engages a coupling structure and is compressively retained within a primary capsule, which constrains the prosthetic heart valve in a compressed arrangement. In the partially deployed state, the prosthetic heart valve engages the coupling structure and is compressively retained within a secondary capsule, which constrains the prosthetic heart valve to a partially deployed arrangement. The partially deployed arrangement is less compressed than the compressed arrangement and less expanded than a deployed arrangement. In the deployed state, the primary and secondary capsules are retracted from over the prosthetic heart valve, which expands to the deployed arrangement and is released from the coupling structure.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: March 16, 2021
    Assignee: Medtronic, Inc.
    Inventors: Joel Racchini, Paul Rothstein, Jeffrey Sandstrom
  • Publication number: 20210052383
    Abstract: A delivery system for delivery of an implantable stented device to a body lumen that includes an elongated member having a distal tip and a proximal end portion, a wire connection member positioned between the distal tip and proximal end portion of the elongated member, and a plurality of capturing wires extending from a distal end of the wire connection member. Each of the capturing wires includes a distal end having a lower portion that is moveable relative to an upper portion between an open position and a closed position, and a slot defined by the upper and lower portions when they are in the closed position.
    Type: Application
    Filed: October 5, 2020
    Publication date: February 25, 2021
    Inventor: Paul Rothstein
  • Publication number: 20210045875
    Abstract: Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.
    Type: Application
    Filed: November 2, 2020
    Publication date: February 18, 2021
    Inventors: Jason QUILL, Cynthia Clague, Michael Green, Alexander J. Hill, Ana Menk, Paul Rothstein, Georg Bortlein
  • Publication number: 20200405481
    Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.
    Type: Application
    Filed: September 10, 2020
    Publication date: December 31, 2020
    Inventors: Paul Rothstein, Jeffrey Sandstrom, Geoffrey Orth
  • Patent number: 10869761
    Abstract: A heart valve therapy system including a delivery device and a stented valve. The delivery device includes an outer sheath, an inner shaft, an optional hub assembly, and a plurality of tethers. In a delivery state, a stent frame of the prosthesis is crimped over the inner shaft and maintained in a compressed condition by the outer sheath. The tethers are connected to the stent frame. In a partial deployment state, the outer sheath is at least partially withdrawn, allowing the stent frame to self-expand. Tension in the tethers prevents the stent frame from rapidly expanding and optionally allowing recapture. Upon completion of the stent frame expansion, the tethers are withdrawn.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: December 22, 2020
    Assignee: Medtronic Vascular Galway
    Inventors: Marian Creaven, Marc Anderson, Kate Corish, Declan Costello, Niall Duffy, Joshua Dwork, John Gallagher, Patrick Griffin, Gavin Kenny, Deirdre McGowan Smyth, John Milroy, Jason Quill, Herinaina Rabarimanantsoa Jamous, Paul Rothstein, Jeffrey Sandstrom, Edmond Sheahan, Frank White
  • Patent number: 10856932
    Abstract: Device and method for sub-xiphoid ablation of patient tissue. A sub-xiphoid access clamp has a handle, an elongate neck coupled to the handle and first and second opposing jaws. The first and second opposing jaws have first and second opposing relief segments being generally co-planar and concave with respect to one another to form a void therebetween, and first and second opposing elongate ablation elements positioned along the first and second opposing jaws and distal of the first and second opposing relief segments relative to the handle. The first and second opposing jaws are articulate between a closed position and an open position to admit, at least in part, a second portion of tissue of the patient within the void created by the first and second opposing relief segments while the first portion of tissue is positioned between the first and second ablation elements in the closed position.
    Type: Grant
    Filed: May 18, 2017
    Date of Patent: December 8, 2020
    Assignee: Medtronic Inc.
    Inventors: Mark Stewart, Thomas Daigle, David Francischelli, John Liddicoat, Paul Rothstein, Steven F. Bolling
  • Publication number: 20200375739
    Abstract: The present disclosure relates to numerous delivery devices and methods for transcatheter prosthetic heart valve loading, deployment and delivery utilizing at least one suture. Disclosed delivery devices utilize improved suture routing methods and configurations that reduce suture tangling and also provide the ability to adjust the prosthetic heart valve expansion and contraction prior to the final release of the prosthetic heart valve from the delivery device.
    Type: Application
    Filed: August 19, 2020
    Publication date: December 3, 2020
    Applicant: Medtronic Vascular, Inc.
    Inventor: Paul Rothstein
  • Patent number: 10849749
    Abstract: Systems and methods for modifying a heart valve annulus in a minimally invasive surgical procedure. A helical anchor is provided, having a memory set to a coiled shape or state. The helical anchor is further configured to self-revert from a substantially straight state to the coiled state. The helical anchor is loaded within a needle that constrains the helical anchor to the substantially straight state. The needle is delivered to the valve annulus and inserted into tissue of the annulus. The helical anchor is then deployed from the needle (e.g., the needle is retracted from over the helical anchor). Once deployed, the helical anchor self-transitions toward the coiled shape, cinching engaged tissue of the valve annulus.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: December 1, 2020
    Assignee: MEDTRONIC, INC.
    Inventors: Jason Quill, Cynthia Clague, Michael Green, Alexander J. Hill, Ana Menk, Paul Rothstein, Georg Bortlein
  • Publication number: 20200345490
    Abstract: Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature. The cord is tensioned to crimp the prosthesis to a compressed condition for delivery to a target site. Tension is lessened to allow the prosthesis to self-expand. In a tethered and expanded state in which the prosthesis has self-expanded and is connected to the spindle by the cord, the lateral control feature directs the spindle to a prescribed location relative to the prosthesis appropriate for a functional evaluation of the prosthesis. In some embodiments, the spindle is directed to a center of the prosthesis; in other embodiments, the spindle is held at a commissure of the prosthesis. The lateral control features of the present disclosure assume numerous forms.
    Type: Application
    Filed: July 21, 2020
    Publication date: November 5, 2020
    Applicant: Medtronic Vascular, Inc.
    Inventors: Jill Mendelson, Michele Silver, Michael Gloss, Timothy Groen, Paul Rothstein, Jeffrey Sandstrom, Phil Haarstad, Joel Racchini, David Blaeser
  • Publication number: 20200337839
    Abstract: A delivery system for percutaneously deploying a valve prosthesis. The system includes a catheter assembly including a delivery sheath capsule and a handle having an oscillating device. The capsule is configured to compressively retain the valve prosthesis during implantation. After the valve prosthesis is partially exposed during implantation, the oscillating device can create a vibratory motion to reduce the friction between the valve prosthesis and the delivery sheath capsule in order to recapture the valve prosthesis.
    Type: Application
    Filed: July 9, 2020
    Publication date: October 29, 2020
    Inventors: Jason Quill, Paul Rothstein, Thomas Secord, Byron Johnson
  • Patent number: 10813755
    Abstract: The disclosure relates to transcatheter stented prosthesis delivery devices including transition elements that route, constrain, support and reduce damage to tension member wear as tension in the tension members is varied to adjust the compression of a stented prosthesis loaded onto the delivery device. Various disclosed tension elements include inserts, edge treatments and guides proximate a distal portion of the delivery device upon which the stented prosthesis is loaded. In some embodiments, the transition feature is positioned proximate a location where at least one tension member transitions from a first orientation that is not parallel to the distal portion to a second orientation that is generally parallel to the distal portion. Further embodiments disclose configurations and methods of selectively locking and unlocking a longitudinal and/or rotational position of the stent frame with respect to the distal portion of the delivery device.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: October 27, 2020
    Assignee: Medtronic, Inc.
    Inventors: Michael Gloss, Patrick Griffin, Paul Rothstein, Jeffrey Sandstrom, Brendan Vaughan, Stephen Montgomery, Alan McGuinn