Patents by Inventor Paul Rothstein

Paul Rothstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11903828
    Abstract: Delivery devices for a stented prosthetic heart valve. The delivery device includes a spindle, at least one cord, and a lateral control feature. The cord is tensioned to crimp the prosthesis to a compressed condition for delivery to a target site. Tension is lessened to allow the prosthesis to self-expand. In a tethered and expanded state in which the prosthesis has self-expanded and is connected to the spindle by the cord, the lateral control feature directs the spindle to a prescribed location relative to the prosthesis appropriate for a functional evaluation of the prosthesis. In some embodiments, the spindle is directed to a center of the prosthesis; in other embodiments, the spindle is held at a commissure of the prosthesis. The lateral control features of the present disclosure assume numerous forms.
    Type: Grant
    Filed: July 21, 2020
    Date of Patent: February 20, 2024
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventors: Jill Mendelson, Michele Silver, Michael Gloss, Timothy Groen, Paul Rothstein, Jeffrey Sandstrom, Phil Haarstad, Joel Racchini, David Blaeser
  • Publication number: 20230397986
    Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.
    Type: Application
    Filed: August 28, 2023
    Publication date: December 14, 2023
    Inventors: Paul Rothstein, Jeffrey Sandstrom, Geoffrey Orth
  • Patent number: 11826250
    Abstract: A delivery system for percutaneously deploying a valve prosthesis. The system includes a catheter assembly including a delivery sheath capsule and a handle having an oscillating device. The capsule is configured to compressively retain the valve prosthesis during implantation. After the valve prosthesis is partially exposed during implantation, the oscillating device can create a vibratory motion to reduce the friction between the valve prosthesis and the delivery sheath capsule in order to recapture the valve prosthesis.
    Type: Grant
    Filed: July 9, 2020
    Date of Patent: November 28, 2023
    Assignee: Medtronic, Inc.
    Inventors: Jason Quill, Paul Rothstein, Thomas Secord, Byron Johnson
  • Publication number: 20230301781
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Application
    Filed: May 18, 2023
    Publication date: September 28, 2023
    Inventors: Kshitija GARDE, Joel RACCHINI, Paul ROTHSTEIN, Jeffrey SANDSTROM
  • Patent number: 11737869
    Abstract: An integrated valve prosthesis includes an anchor stent, a tether component, and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the annulus of an aortic valve or the aorta. The valve component includes a valve frame and a prosthetic valve coupled to the valve frame, and is configured to be deployed within the anchor stent. The tether component includes a first end coupled to the anchor stent and a second end coupled to the valve frame. In the delivery configuration, the tether component extends in a first direction from the anchor stent to the valve component, and in the deployed configuration, the tether component extends in a second direction from the anchor stent to the valve component. The second direction is generally opposite the first direction. The tether component may set the location of the valve component relative to the anchor stent.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: August 29, 2023
    Assignee: Medtronic, Inc.
    Inventors: Paul Rothstein, Jeffrey Sandstrom, Geoffrey Orth
  • Patent number: 11712337
    Abstract: A delivery system for delivery of an implantable stented device to a body lumen that includes an elongated member having a distal tip and a proximal end portion, a wire connection member positioned between the distal tip and proximal end portion of the elongated member, and a plurality of capturing wires extending from a distal end of the wire connection member. Each of the capturing wires includes a distal end having a lower portion that is moveable relative to an upper portion between an open position and a closed position, and a slot defined by the upper and lower portions when they are in the closed position.
    Type: Grant
    Filed: October 5, 2020
    Date of Patent: August 1, 2023
    Assignee: Medtronic, Inc.
    Inventor: Paul Rothstein
  • Publication number: 20230233318
    Abstract: A modular valve prosthesis includes an anchor stent and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the aorta and a proximal arm component extending from a proximal end of the tubular frame member and configured to be deployed in the sinuses of the aortic valve. The anchor stent further includes attachment members extending from an internal surface of the tubular frame member. The valve component includes a valve frame configured to be deployed within the tubular frame member of the anchor stent such that the valve frame engages with the attachment members of the tubular frame member and a prosthetic valve coupled to the valve frame.
    Type: Application
    Filed: April 2, 2023
    Publication date: July 27, 2023
    Inventor: Paul Rothstein
  • Patent number: 11690713
    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.
    Type: Grant
    Filed: June 3, 2020
    Date of Patent: July 4, 2023
    Assignee: Medtronic CV Luxembourg S.A.R.L.
    Inventors: Kshitija Garde, Joel Racchini, Paul Rothstein, Jeffrey Sandstrom
  • Patent number: 11672656
    Abstract: A system for percutaneous delivery of a stented prosthetic heart valve. The system includes a delivery device with a self-expanding prosthetic heart valve attached thereto and a delivery sheath with an opening on a distal end thereof. The delivery sheath includes a funnel on a proximal end thereof. The delivery device is inserted into the funnel of the delivery sheath. As the delivery device is advanced into the funnel, the expanded heart valve is compressed by the shape of the funnel into a crimped arrangement. The delivery device further advances the heart valve distally within the delivery sheath past the delivery sheath opening. The delivery device is advanced relative to the delivery sheath in transitioning the heart valve from a crimped arrangement to the expanded and deployed arrangement.
    Type: Grant
    Filed: June 25, 2019
    Date of Patent: June 13, 2023
    Inventors: Devin Gosal, Susheel Deshmukh, Philip Haarstad, Joel Racchini, Finn Rinne, Paul Rothstein, Jeffrey Sandstrom
  • Patent number: 11672653
    Abstract: A prosthesis for implantation within a native valve is disclosed. The prosthesis includes a frame defining a lumen, and a tubular component formed of a flexible sheet that is attached to the frame to extend from a first end of the frame, wherein an interior of the tubular component is configured to support a prosthetic valve and is in fluid communication with the lumen of the frame. The prosthesis also includes a wire at least partially slidably disposed within the flexible sheet of the tubular component and operable to transition the tubular component into a deployed configuration that at least partially engages tissue at the native valve.
    Type: Grant
    Filed: May 19, 2020
    Date of Patent: June 13, 2023
    Assignee: Medtronic, Inc.
    Inventors: Paul Rothstein, Jeffrey Sandstrom
  • Publication number: 20230149160
    Abstract: A transcatheter prosthesis includes a stent, a prosthetic valve component, and an anti-paravalvular leakage component. The anti-paravalvular leakage component is coupled to the stent and includes an inner skirt, an outer wrap, a cavity, an opening, and a one-way valve. The inner skirt is disposed on an inner surface of the stent and has an inflow end and a downstream end. The outer wrap is disposed around an outer surface of the stent and has an inflow end coupled to the inflow end of the inner skirt and a downstream end. The cavity is formed between an outer surface of the inner skirt and an inner surface of the outer wrap. An opening is disposed between the inner skirt and the outer wrap. The one-way valve includes a flap at the opening configured to open to allow blood flow into the cavity but prevent blood flow out of the cavity.
    Type: Application
    Filed: January 13, 2023
    Publication date: May 18, 2023
    Inventors: Cynthia Clague, Ana Menk, Timothy Petersen, Paul Rothstein, Stephen Roller
  • Publication number: 20230145819
    Abstract: The disclosure relates to transcatheter stented prosthesis delivery devices including transition elements that route, constrain, support and reduce damage to tension member wear as tension in the tension members is varied to adjust the compression of a stented prosthesis loaded onto the delivery device. Various disclosed tension elements include inserts, edge treatments and guides proximate a distal portion of the delivery device upon which the stented prosthesis is loaded. In some embodiments, the transition feature is positioned proximate a location where at least one tension member transitions from a first orientation that is not parallel to the distal portion to a second orientation that is generally parallel to the distal portion. Further embodiments disclose configurations and methods of selectively locking and unlocking a longitudinal and/or rotational position of the stent frame with respect to the distal portion of the delivery device.
    Type: Application
    Filed: January 6, 2023
    Publication date: May 11, 2023
    Inventors: Michael Gloss, Patrick Griffin, Paul Rothstein, Jeffrey Sandstrom, Brendan Vaughan, Stephen Montgomery, Alan McGuinn
  • Patent number: 11628061
    Abstract: A modular valve prosthesis includes an anchor stent and a valve component. The anchor stent includes a self-expanding tubular frame member configured to be deployed in the aorta and a proximal arm component extending from a proximal end of the tubular frame member and configured to be deployed in the sinuses of the aortic valve. The anchor stent further includes attachment members extending from an internal surface of the tubular frame member. The valve component includes a valve frame configured to be deployed within the tubular frame member of the anchor stent such that the valve frame engages with the attachment members of the tubular frame member and a prosthetic valve coupled to the valve frame.
    Type: Grant
    Filed: April 5, 2020
    Date of Patent: April 18, 2023
    Assignee: MEDTRONIC, INC.
    Inventor: Paul Rothstein
  • Patent number: 11617651
    Abstract: The present disclosure relates to numerous delivery devices and methods for transcatheter prosthetic heart valve loading, deployment and delivery utilizing at least one suture. Disclosed delivery devices utilize improved suture routing methods and configurations that reduce suture tangling and also provide the ability to adjust the prosthetic heart valve expansion and contraction prior to the final release of the prosthetic heart valve from the delivery device.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: April 4, 2023
    Assignee: MEDTRONIC VASCULAR, INC.
    Inventor: Paul Rothstein
  • Patent number: 11583397
    Abstract: A transcatheter prosthesis includes a stent, a prosthetic valve component, and an anti-paravalvular leakage component. The anti-paravalvular leakage component is coupled to the stent and includes an inner skirt, an outer wrap, a cavity, an opening, and a one-way valve. The inner skirt is disposed on an inner surface of the stent and has an inflow end and a downstream end. The outer wrap is disposed around an outer surface of the stent and has an inflow end coupled to the inflow end of the inner skirt and a downstream end. The cavity is formed between an outer surface of the inner skirt and an inner surface of the outer wrap. An opening is disposed between the inner skirt and the outer wrap. The one-way valve includes a flap at the opening configured to open to allow blood flow into the cavity but prevent blood flow out of the cavity.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: February 21, 2023
    Assignee: Medtronic, Inc.
    Inventors: Cynthia Clague, Ana Menk, Timothy Petersen, Paul Rothstein, Stephen Roller
  • Patent number: 11571302
    Abstract: The disclosure relates to transcatheter stented prosthesis delivery devices including transition elements that route, constrain, support and reduce damage to tension member wear as tension in the tension members is varied to adjust the compression of a stented prosthesis loaded onto the delivery device. Various disclosed tension elements include inserts, edge treatments and guides proximate a distal portion of the delivery device upon which the stented prosthesis is loaded. In some embodiments, the transition feature is positioned proximate a location where at least one tension member transitions from a first orientation that is not parallel to the distal portion to a second orientation that is generally parallel to the distal portion. Further embodiments disclose configurations and methods of selectively locking and unlocking a longitudinal and/or rotational position of the stent frame with respect to the distal portion of the delivery device.
    Type: Grant
    Filed: June 25, 2020
    Date of Patent: February 7, 2023
    Assignee: MEDTRONIC, INC.
    Inventors: Michael Gloss, Patrick Griffin, Paul Rothstein, Jeffrey Sandstrom, Brendan Vaughan, Stephen Montgomery, Alan McGuinn
  • Publication number: 20220331105
    Abstract: A delivery system for transcatheter implantation of a heart valve prosthesis. The delivery system includes an outer sheath component defining a lumen therethrough, an elongate tube having at least two flat wires longitudinally extending from a distal end thereof, and self-expanding first and second frames disposed in series within a distal portion of the outer sheath component and held in a compressed delivery configuration therein. The elongate tube and the at least two flat wires are slidably disposed within the lumen of the outer sheath component. In the compressed delivery configuration the at least two flat wires longitudinally extend along exterior portions of the first and second frames and are woven through adjacent ends of the first and second frames to releasably couple them to each other. Proximal retraction of the at least two flat wires from the first and second frames releases at least the first frame from the delivery system.
    Type: Application
    Filed: July 6, 2022
    Publication date: October 20, 2022
    Inventors: Paul ROTHSTEIN, James R. KEOGH
  • Patent number: 11413172
    Abstract: An anchor stent assembly to be used with a valve component includes a generally tubular frame having a first end and a second end, the frame defining a central passage and a central axis. A secondary passage is defined between n inner surface of the frame and an outer surface of an inner rib disposed closer to the central axis than the frame. An extension tube is disposed through the secondary passage. The extension tube includes an extension tube lumen having a first opening at a first end of the extension tube and a second opening at a second end of the extension tube.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: August 16, 2022
    Assignee: Medtronic, Inc.
    Inventors: Shishira Nagesh, Paul Rothstein
  • Patent number: 11413144
    Abstract: A delivery system for transcatheter implantation of a heart valve prosthesis. The delivery system includes an outer sheath component defining a lumen therethrough, an elongate tube having at least two flat wires longitudinally extending from a distal end thereof, and self-expanding first and second frames disposed in series within a distal portion of the outer sheath component and held in a compressed delivery configuration therein. The elongate tube and the at least two flat wires are slidably disposed within the lumen of the outer sheath component. In the compressed delivery configuration the at least two flat wires longitudinally extend along exterior portions of the first and second frames and are woven through adjacent ends of the first and second frames to releasably couple them to each other. Proximal retraction of the at least two flat wires from the first and second frames releases at least the first frame from the delivery system.
    Type: Grant
    Filed: November 6, 2019
    Date of Patent: August 16, 2022
    Assignee: MEDTRONIC, INC.
    Inventors: Paul Rothstein, James R. Keogh
  • Patent number: 11219434
    Abstract: A method of surgical dissection of tissue with a dissector comprising: an elongate shaft comprising a proximal portion and a distal portion, wherein the distal portion comprises a plurality of segments that articulate with respect to one another and the plurality of segments includes a distal segment having a distal end; and a handle attached to the proximal portion of the shaft, wherein the handle comprises controls for articulating the plurality of segments of the distal portion of the shaft with respect to one another, comprising the steps of: positioning the distal end of the dissector in a body; advancing the distal end through the body to dissect tissue; and simultaneously articulating the plurality of segments with respect to one another. A method of surgical dissection of tissue and guiding a second device to a desired physiological location with a first device.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: January 11, 2022
    Assignee: Medtronic, Inc.
    Inventors: Mark Thompson, Darrin Dickerson, Brett S. Bowman, Christopher F. Kelly, William W. Malecki, David Francischelli, Mark Stewart, Thomas Daigle, Douglas Gubbin, David Kim, Paul Rothstein, Adam Podbelski, Christopher Plott, Benjamin K. Yaffe