Abstract: At least some aspects of the present disclosure are directed to systems and methods of an agronomic condition prediction and alerts engine. In some cases, the engine receives a set of field data and the set of field data includes one or more of geospatial data, crop data, user data, agronomic data, and weather data. In some cases, the engine retrieves a set of agronomic profile data from an agronomic data repository, where each of the set of agronomic profile data representing an agronomic condition and comprising one or more of geospatial profile, crop profile, pest profile, agronomic profile, user data profile, and weather profile corresponding to the agronomic condition. In some embodiments, the engine applies a multivariable processing to the set of field data using the set of agronomic profile data and generates an agronomic condition indicator indicative of one or more agronomic conditions.

Abstract: At least some embodiments of the present disclosure are directed to systems and methods for data analytics for a community and/or a campaign. In some cases, a process implemented by a data analytics system includes the steps of: providing an input data protocol to a plurality of data providers of a campaign; receiving a plurality of datasets from the plurality of data providers; processing the plurality of datasets to remove sensitive information contained in the plurality of agronomic datasets; aggregating the plurality of processed datasets to generate an aggregated dataset; and allowing a plurality of participants of the campaign to access the aggregated dataset.

Abstract: At least some aspects of the present disclosure are directed to systems and methods of an agronomic condition prediction and alerts engine. In some cases, the engine receives a set of field data and the set of field data includes one or more of geospatial data, crop data, user data, agronomic data, and weather data. In some cases, the engine retrieves a set of agronomic profile data from an agronomic data repository, where each of the set of agronomic profile data representing an agronomic condition and comprising one or more of geospatial profile, crop profile, pest profile, agronomic profile, user data profile, and weather profile corresponding to the agronomic condition. In some embodiments, the engine applies a multivariable processing to the set of field data using the set of agronomic profile data and generates an agronomic condition indicator indicative of one or more agronomic conditions.

Abstract: A system, method, and operating environment facilitate providing year-round agriculture management services to a grower. The method may include determining a geographic location of a field associated with a grower; obtaining information representative of an event prediction, such as a weather forecast, corresponding to the geographic location from one or more information sources; obtaining grower data associated with the grower; predicting an agronomic consequence based on the event prediction and the grower data; and providing a notification of the event prediction to the grower.

Abstract: At least some aspects of the present disclosure are directed to systems and methods of an agronomic condition prediction and alerts engine. In some cases, the engine receives a set of field data and the set of field data includes one or more of geospatial data, crop data, user data, agronomic data, and weather data. In some cases, the engine retrieves a set of agronomic profile data from an agronomic data repository, where each of the set of agronomic profile data representing an agronomic condition and comprising one or more of geospatial profile, crop profile, pest profile, agronomic profile, user data profile, and weather profile corresponding to the agronomic condition. In some embodiments, the engine applies a multivariable processing to the set of field data using the set of agronomic profile data and generates an agronomic condition indicator indicative of one or more agronomic conditions.

Abstract: Acid resistant Oligomers suitable for oral administration, orally acceptable formulations of such Oligomers and preparation of pharmaceutical formations of such Oligomers are provided.

Abstract: A composition for inactivating a target nucleic acid which comprises an oligonucleoside alkyl or arylphosphonate analogue which is complementary to the sequence of the target nucleic acid and includes a functional group which reacts with the target nucleic acid to render the target nucleic acid inactive or nonfunctional.

Abstract: A specific segment of double stranded DNA may be detected or recognized by formation of a triple helix structure using an Oligomer comprising an 8-modified purine base such as 8-oxo-adenine or 8-oxo-guanine to form a detectable triple helix complex. Function or expression of double stranded DNA segments may be prevented by triple helix formation. Novel Oligomers comprising an 8-modified purine base are useful in triple helix formation, and may be optionally derivatized with DNA modifying groups.

Abstract: A graphic display for chroma keyer controls presents background hue as a radial spoke of an outer chroma vector circle, with selectivity being displayed as a wedge about the radial spoke. Foreground suppression may be added to the graphic display by providing a concentric inner chroma vector circle with the foreground suppression hue being a radial spoke of the inner circle and foreground selectivity being a wedge within the inner circle about such radial spoke. That portion of the outer circle that is overlapped by the inner circle is suppressed, or rendered invisible, so that the background chroma information appears as a torus about the inner chroma vector circle.

Abstract: An oligonucleotide or analog thereof including a single cytidine residue at a selected position and having one or more cytidine residues which are 5-methyl substituted. The cytidine nucleus can be selectively transaminated to include an aminoalkyl or carboxyalkyl group as a linker for other functional groups which can be used to form DNA duplexes and triplexes.

Abstract: A process for selectively controlling or interfering with the effect or function of foreign nucleic acid in the presence of otherwise normal living cells which comprises determining the base sequence for said nucleic acid and binding the said nucleic acid with an appropriately prepared nonionic oligonucleoside alkyl or arylphosphonate analogue which is complementary to the indicated sequence of the foreign nucleic acid.

Abstract: Oligonucleoside-3'-alkyl or aryl phosphonates are prepared by condensing (i) a 5'-protected nucleoside 3'-alkyl or aryl phosphonic imidazolide with (ii) a nucleoside or oligomer which is attached through its 3'-position to a polymer support. The process is advantageously carried out in the presence of tetrazole.

Abstract: A nucleic acid-protein conjugate which is specific with respect to a selected living cell is prepared by linking said nucleic acid to a protein specific to said living cell.

Abstract: A process for selectively controlling or interfering with the effect or function of foreign nucleic acid in the presence of otherwise normal living cells which comprises determining the base sequence for the nucleic acid and binding the nucleic acid with an appropriately prepared nonionic oligonucleoside alkyl or arylphosphonate analogue which is complementary to the indicated sequence of the foreign nucleic acid.

Abstract: Process for synthesizing deoxyribonucleoside methylphosphonates on polystyrene polymer supports which involves condensing 5'-dimethoxytrityldeoxynucleoside 3'-methylphosphonates. The oligomers are removed from the support and the base protecting groups hydrolyzed by treatment with ethylenediamene in ethanol, which avoids hydrolysis of the methylphosphonate linkages. Two types of oligomers are synthesized: those containing only methylphosphonate linkages, d-Np(Np).sub.n N, and those which terminate with a 5' nucleotide residue, dNp(Np).sub.n N. The latter oligomers can be phosphorylated by polynucleotide kinase, and are separated by polyacrylamide gel electrophoresis according to their chain length. Piperidine randomly cleaves the oligomer methylphosphonate linkages and generates a series of shorter oligomers whose number corresponds to the length of the original oligomer. Apurinic sites introduced by acid treatment spontaneously hydrolyze to give oligomers which terminate with free 3' and 5'-OH groups.

Abstract: Oligonucleoside alkyl-- or aryl phosphonates are nonionic analogues of nucleic acid which possess unique physical and biological properties. These properties enable the analogues to enter living cells intact and to bind with specifically selected nucleic acids within the cell. As a result, the analogues can specifically inhibit the function or expression of a preselected nucleic acid sequence. Thus the analogues could be used to specifically inhibit the growth of tumor cells or replication of viruses in infected cells.

Abstract: Portions of the confining frame of a water bed are made so they can be tilted away from the water-filled mattress of that water bed to facilitate the positioning, and the smoothing, of a cover for that water-filled mattress adjacent the sides and end of that water-filled mattress.