Patents by Inventor Paul Schlesinger

Paul Schlesinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of making trabecular bone
    Patent number: 11060060
    Abstract: Provided herein are methods of producing trabecular bone material, such as trabecular bone or trabecular bone matrix and cells useful in preparing the trabecular bone material.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: July 13, 2021
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, The United States Government as represented by the Department of Veterans Affairs, University of Chicago, Washington University
    Inventors: Harry Colbert Blair, Quitterie Larrouture, Irina L. Tourkova, Deborah J. Nelson, Paul Schlesinger
  • Method of Making Trabecular Bone
    Publication number: 20180258399
    Abstract: Provided herein are methods of producing trabecular bone material, such as trabecular bone or trabecular bone matrix and cells useful in preparing the trabecular bone material.
    Type: Application
    Filed: September 16, 2016
    Publication date: September 13, 2018
    Inventors: Harry Colbert Blair, Quitterie Larrouture, Irina L. Tourkova, Deborah J. Nelson, Paul Schlesinger
  • NANOPARTICLE DELIVERY SYSTEMS FOR CYTOLYTIC PEPTIDE PRODRUGS
    Publication number: 20160296628
    Abstract: Compositions and methods of treatment using conjugates of pore-forming compounds coupled to blocking segments by protease-cleavable linkers and absorbed onto lipid-based delivery vehicles are described. These compositions and methods permit personalization of treatment.
    Type: Application
    Filed: January 22, 2016
    Publication date: October 13, 2016
    Applicant: Washington University
    Inventors: Samuel A. WICKLINE, Andrew JALLOUK, Paul SCHLESINGER, Hua PAN
  • Nanoparticle delivery systems for membrane-integrating peptides
    Patent number: 8496945
    Abstract: Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
    Type: Grant
    Filed: May 17, 2011
    Date of Patent: July 30, 2013
    Assignee: Washington University
    Inventors: Paul Schlesinger, Neelesh Soman, Gregory Lanza, Samuel A. Wickline
  • NANOPARTICLE DELIVERY SYSTEMS FOR MEMBRANE-INTEGRATING PEPTIDES
    Publication number: 20120128590
    Abstract: Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
    Type: Application
    Filed: May 17, 2011
    Publication date: May 24, 2012
    Applicant: Washington University
    Inventors: Paul Schlesinger, Neelesh Soman, Gregory Lanza, Samuel A. Wickline
  • Nanoparticle delivery systems comprising a hydrophobic core and a lipid/surfactant layer comprising a membrane-lytic peptide
    Patent number: 7943168
    Abstract: Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
    Type: Grant
    Filed: March 5, 2008
    Date of Patent: May 17, 2011
    Assignee: Washington University
    Inventors: Paul Schlesinger, Neelesh Soman, Gregory Lanza, Samuel A. Wickline
  • NANOPARTICLE DELIVERY SYSTEMS FOR MEMBRANE-INTEGRATING PEPTIDES
    Publication number: 20080274056
    Abstract: Compositions which comprise emulsions of nanoparticles for delivery of membrane-integrating peptides are described. The nanoparticles comprise a liquid hydrophobic core coated with a lipid/surfactant layer which contains the membrane-integrating peptides. Methods to use such compositions are also described.
    Type: Application
    Filed: March 5, 2008
    Publication date: November 6, 2008
    Inventors: Paul Schlesinger, Neelesh Soman, Gregory Lanza, Samuel A. Wickline