Abstract: An embodiment includes a method of multi-leg transaction processing. The method includes receiving from a merchant server, a designation of two or more sub-transactions of a pending multi-leg transaction as a coupled group. The execution of any of the two or more sub-transactions in the coupled group is dependent on prior authorization of each of the two or more sub-transactions. The method includes receiving transaction input used to indicate conditional execution of the multi-leg transaction. Prior to execution of the multi-leg transaction and in substantially real time, the method includes determining whether each of the two or more sub-transactions in the coupled group is authorized. In response to any of the two or more sub-transactions being unauthorized, the method includes preventing execution of the multi-leg transaction. In response to authorization of each of the two or more sub-transactions, the method includes executing the multi-leg transaction non-sequentially.

Abstract: An embodiment includes a method of multi-leg transaction processing. The method includes receiving from a merchant server, a designation of two or more sub-transactions of a pending multi-leg transaction as a coupled group. The execution of any of the two or more sub-transactions in the coupled group is dependent on prior authorization of each of the two or more sub-transactions. The method includes receiving transaction input used to indicate conditional execution of the multi-leg transaction. Prior to execution of the multi-leg transaction and in substantially real time, the method includes determining whether each of the two or more sub-transactions in the coupled group is authorized. In response to any of the two or more sub-transactions being unauthorized, the method includes preventing execution of the multi-leg transaction. In response to authorization of each of the two or more sub-transactions, the method includes executing the multi-leg transaction non-sequentially.

Abstract: A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients.

Abstract: A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients.

Abstract: A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients.

Abstract: A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients.

Abstract: Damage to tissue, such as ischemic damage, can cause the release of mitochondrial markers. The released markers can be detected in a sample taken from a subject, indicating that the subject has suffered damage.

Abstract: Methods and assays for monitoring the cardiac health of a subject are provided. The method involves the detection of a urotensin surrogate in a sample leading to a more accurate and reliable diagnosis of early or late stages of decompensated heart failure, heart failure, risk of a heart failur in a subject than the measurement of the cyclic peptide of urotensin alone.

Abstract: An inflammatory peptide can be a marker for cardiac ischemia.

Abstract: A device for remote management of patients suffering from heart failure and hypertension can measure one or more biomarker. The device aids in monitoring the efficacy and safety of treatment in such patients.

Abstract: Enhanced extraction of solubilized antigens is obtained from bacteria such as Chlamydia and Neisseri by the use of a buffer containing a zwitterionic surface active agent, especially CHAPS or CHAPSO, in the absence of divalent cations. The extraction is conducted at elevated temperature, and provides a sample useful in assays for the presence of the bacteria.