Patents by Inventor Paul Sigala

Paul Sigala has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combination artemisinin and chemiluminescent photodynamic therapy and uses therefor
    Patent number: 10925963
    Abstract: Photodynamic therapy-based methods of treating diseases such as cancer and malaria are disclosed. These methods include administering 5-aminolevulinic acid (ALA), luminol and artemisinin (ART). ART and ALA administered in combination with luminol can kill malaria parasites without host toxicity. In some aspects, the methods further include administration of a luminol enhancer such as 4-iodophenol. The disclosed methods can also be used to remove potential malaria pathogens from the blood supply.
    Type: Grant
    Filed: June 22, 2016
    Date of Patent: February 23, 2021
    Inventors: Daniel E. Goldberg, Paul Sigala
  • COMBINATION ARTEMISININ AND CHEMILUMINESCENT PHOTODYNAMIC THERAPY AND USES THEREFOR
    Publication number: 20160367674
    Abstract: Photodynamic therapy-based methods of treating diseases such as cancer and malaria are disclosed. These methods include administering 5-aminolevulinic acid (ALA), luminol and artemisinin (ART). ART and ALA administered in combination with luminol can kill malaria parasites without host toxicity. In some aspects, the methods further include administration of a luminol enhancer such as 4-iodophenol. The disclosed methods can also be used to remove potential malaria pathogens from the blood supply.
    Type: Application
    Filed: June 22, 2016
    Publication date: December 22, 2016
    Inventors: Daniel E. Goldberg, Paul Sigala