Patents by Inventor Paul Slusarewicz

Paul Slusarewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CROSSLINKER ENHANCED REPAIR OF KNEE MENISCUS
    Publication number: 20150217025
    Abstract: A method of treating a tear in a knee meniscus of a patient. The method includes exposing the torn knee meniscus to a protein crosslinker during surgery to repair the tear. Also provided is a fixation device for the surgical repair of tears of the meniscus of the knee, where the device contains one or more protein crosslinking reagents.
    Type: Application
    Filed: April 13, 2015
    Publication date: August 6, 2015
    Applicant: Orthopeutics, L.P.
    Inventors: Thomas P. Hedman, Paul Slusarewicz
  • CROSSLINKER ENHANCED REPAIR OF KNEE MENISCUS
    Publication number: 20130085569
    Abstract: A method of treating a tear in a knee meniscus of a patient. The method includes exposing the torn knee meniscus to a protein crosslinker during surgery to repair the tear. Also provided is a fixation device for the surgical repair of tears of the meniscus of the knee, where the device contains one or more protein crosslinking reagents.
    Type: Application
    Filed: May 26, 2011
    Publication date: April 4, 2013
    Applicant: Orthopeutics, L.P.
    Inventors: Thomas P. Hedman, Paul Slusarewicz
  • Formulations for nonsurgical exogenous crosslink therapy
    Patent number: 8283322
    Abstract: Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.
    Type: Grant
    Filed: July 1, 2009
    Date of Patent: October 9, 2012
    Assignee: Orthopeutics, LP
    Inventors: Paul Slusarewicz, Thomas P. Hedman
  • Formulations for nonsurgical exogenous crosslink therapy
    Patent number: 8198248
    Abstract: Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.
    Type: Grant
    Filed: September 3, 2008
    Date of Patent: June 12, 2012
    Assignee: Orthopeutics, LP
    Inventors: Thomas P. Hedman, Paul Slusarewicz
  • Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
    Patent number: 8119599
    Abstract: A method of treatment of native, non-denatured tissue to increase resistance to tearing, fissuring, rupturing, and/or delamination, comprising the step of: contacting at least a portion of the tissue with an effective amount of a reagent that increases crosslinks in the tissue.
    Type: Grant
    Filed: October 17, 2007
    Date of Patent: February 21, 2012
    Assignee: Orthopeutics, L.P.
    Inventors: Thomas P. Hedman, Paul Slusarewicz
  • FORMULATIONS FOR NONSURGICAL EXOGENOUS CROSSLINK THERAPY
    Publication number: 20100040594
    Abstract: Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.
    Type: Application
    Filed: July 1, 2009
    Publication date: February 18, 2010
    Inventors: Paul Slusarewicz, Thomas P. Hedman
  • Formulations for Nonsurgical Exogenous Crosslink Therapy
    Publication number: 20100041616
    Abstract: Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.
    Type: Application
    Filed: September 3, 2008
    Publication date: February 18, 2010
    Inventors: Thomas P. Hedman, Paul Slusarewicz
  • FORMULATIONS FOR NONSURGICAL EXOGENOUS CROSSLINK THERAPY
    Publication number: 20100040593
    Abstract: Improved methods and compositions for the treatment of native tissues with crosslinkers are provided. The methods and compositions will find particular use in increasing resistance to tearing, fissuring, rupturing, and/or delamination.
    Type: Application
    Filed: August 15, 2008
    Publication date: February 18, 2010
    Inventors: Thomas P. Hedman, Paul Slusarewicz
  • Heat shock protein-based vaccines and immunotherapies
    Patent number: 7420037
    Abstract: Hybrid antigens comprising an antigenic domain and improved heat shock protein binding domains are described which are useful for the induction of an immune response to the antigenic domain and thus can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Grant
    Filed: February 12, 2004
    Date of Patent: September 2, 2008
    Assignee: Antigenics Inc.
    Inventors: Paul Slusarewicz, Sunil Mehta
  • Direct application of non-toxic crosslinking reagents to resist progressive spinal degeneration and deformity
    Publication number: 20080064021
    Abstract: A method of treatment of native, non-denatured tissue to increase resistance to tearing, fissuring, rupturing, and/or delamination, comprising the step of: contacting at least a portion of the tissue with an effective amount of a reagent that increases crosslinks in the tissue.
    Type: Application
    Filed: October 17, 2007
    Publication date: March 13, 2008
    Inventors: Thomas Hedman, Paul Slusarewicz
  • Heat shock protein-based vaccines and immunotherapies
    Patent number: 7309491
    Abstract: Hybrid antigens comprising at least one antigenic domain, at least one heat shock protein binding domain, and at least one improved peptide linker there between are described which are useful for the induction of an immune response to the antigenic domain when administered alone or in a complex with at least one heat shock protein. The hybrid antigens and complexes can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: December 18, 2007
    Assignee: Antigenics Inc.
    Inventors: Paul Slusarewicz, Jessica Baker Flechtner, Sunil Mehta, Kenya Prince-Cohane, Sofija Andjelic, Brian H. Barber
  • Heat shock protein-based vaccines and immunotherapies
    Publication number: 20050214312
    Abstract: Hybrid antigens comprising at least one antigenic domain, at least one heat shock protein binding domain, and at least one improved peptide linker there between are described which are useful for the induction of an immune response to the antigenic domain when administered alone or in a complex with at least one heat shock protein. The hybrid antigens and complexes can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Application
    Filed: April 8, 2004
    Publication date: September 29, 2005
    Inventors: Jessica Flechtner, Kenya Prince-Cohane, Sunil Mehta, Paul Slusarewicz, Sofija Andjelic, Brian Barber
  • Heat shock protein-based vaccines and immunotherapies
    Publication number: 20050202033
    Abstract: Hybrid antigens comprising an antigenic domain and improved heat shock protein binding domains are described which are useful for the induction of an immune response to the antigenic domain and thus can be used to treat infectious diseases and cancers that express an antigen of the antigenic domain.
    Type: Application
    Filed: February 12, 2004
    Publication date: September 15, 2005
    Inventors: Jessica Flechtner, Kenya Prince-Cohane, Sunil Mehta, Paul Slusarewicz, Sofija Andjelic, Brian Barber
  • Treating hair by targeting enzymes
    Publication number: 20020119112
    Abstract: The invention provides the use of a hair benefit agent as an ingredient in a topical hair treatment composition for the purpose of targeting an active endogenous hair fibre enzyme when the composition is applied to the hair, thereby delivering a hair benefit via the interaction of the hair benefit agent with the enzyme.
    Type: Application
    Filed: April 10, 2002
    Publication date: August 29, 2002
    Applicant: UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC.
    Inventors: Margaret Ann Blount, Michael Arthur Davis, Kelly Jackson, Nathalie Noel, Matthew Leslie Pearce, Paul Slusarewicz
  • Treating hair by targeting enzymes
    Patent number: 6399052
    Abstract: The invention provides the use of a hair benefit agent as an ingredient in a topical hair treatment composition for the purpose of targeting an active endogenous hair fiber enzyme when the composition is applied to the hair, thereby delivering a hair benefit via the interaction of the hair benefit agent with the enzyme.
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: June 4, 2002
    Assignee: Unilever Home & Personal Care USA division of Conopco, Inc.
    Inventors: Margaret Ann Blount, Michael Arthur Davis, Kelly Jackson, Nathalie Noel, Matthew Leslie Pearce, Paul Slusarewicz
  • HAIR TREATMENT COMPOSITION COMPRISING A SUGAR OR CARBOHYDRATE FOR THE PURPOSES OF PARTICIPATING IN OXYGEN CONSUMPTION OF A HAIR METHOD AND USE
    Publication number: 20020031483
    Abstract: Use in a topical hair composition of a compound selected from a TCA cycle intermediate, an amino acid which is catabolized to be consumed in the TCA cycle, a fatty acid, a glycolysis product, a sugar or a carbohydrate, for the purposes of participating in the oxygen consumption of a hair follicle.
    Type: Application
    Filed: September 21, 1999
    Publication date: March 14, 2002
    Inventors: JONATHAN SAMUEL BECK, MICHAEL ARTHUR DAVIS, PREYESH PARMAR, PAUL SLUSAREWICZ, GILLIAN ELIZABETH WESTGATE
  • Treating hair by targeting enzymes
    Publication number: 20010031250
    Abstract: The invention provides the use of a hair benefit agent as an ingredient in a topical hair treatment composition for the purpose of targeting an active endogenous hair fiber enzyme when the composition is applied to the hair, thereby delivering a hair benefit via the interaction of the hair benefit agent with the enzyme.
    Type: Application
    Filed: June 11, 2001
    Publication date: October 18, 2001
    Applicant: UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC.
    Inventors: Margaret Ann Blount, Michael Arthur Davis, Kelly Jackson, Nathalie Noel, Matthew Leslie Pearce, Paul Slusarewicz