Abstract: Systems and methods for replacing a native heart valve. An anchor comprises multiple coils adapted to support a heart valve prosthesis. At least one of the coils is normally at a first diameter, and is expandable to a second, larger diameter upon application of radial outward force from within the anchor. An expansible heart valve prosthesis is provided and is configured to be delivered into the anchor and expanded inside the multiple coils. This moves at least one coil from the first diameter to the second diameter while securing the anchor and the heart valve prosthesis relative to each other. The system further includes a seal on the anchor that can prevent at least some blood leakage after implantation of the heart valve prosthesis in the helical anchor. Additional apparatus and methods are disclosed.

Abstract: Systems and methods comprising an anchor adapted to be positioned at a native heart valve annulus. The anchor comprises multiple coils adapted to support a heart valve prosthesis. A flexible outer tube adapted to hold the multiple coils of the anchor can combine with the anchor to form an assembly. A delivery tool adapted to deliver the assembly into position at a native heart valve can be provided and used. The outer tube is adapted to be removed from the multiple coils of the anchor after the coil portions of the anchor are positioned above and/or below the heart valve annulus. Additional apparatus and methods are disclosed.

Abstract: The present disclosure provides medical devices, systems and methods and in particular to devices and methods useful for anchoring graft materials to bodily structures.

Abstract: Systems, devices and methods for removing a blood clot (10) from a blood vessel (12). Various uses of suction pressure and positive pressure, proximal and/or distal to the blood clot (10) assist with clot dislodgement and removal. The pressure(s) may be constant and/or cycled/pulsed to assist with clot dislodgement and/or removal. Various further devices assist with separating the clot (10) from the vessel (12).

Abstract: Various systems, devices and methods associated with the placement of a dock or anchor for a prosthetic valve. The anchor can take the form of an anchor having multiple coils. The distal end portion of the anchor can be spaced radially outwardly from the next adjacent coil to help direct the anchor around native leaflets of a native valve. Various methods include different procedures for delivering the anchor and prosthetic valve.

Abstract: A communications system for providing data communication to a vehicle (10), the communications system comprising: a mobile transport layer proxy (150) located on the vehicle; a parent transport layer proxy (170) located remote from the vehicle; the mobile transport layer proxy being configured to: accept a transport layer connection with a host device (32, 33), the transport layer connection being addressed to a remote server (160); and communicate with the parent transport layer proxy via multiple paths using a multipath transport layer protocol to communicate on behalf of the host device whilst identifying as the mobile transport layer proxy; and the parent transport layer proxy being configured to: communicate with the mobile transport layer proxy using the multipath transport layer protocol; and communicate with the remote server whilst identifying as the parent transport layer proxy to communicate on behalf of the mobile transport layer proxy to permit the host device to communicate with the remote serve

Abstract: Devices, systems and methods to position a prosthetic heart valve such that the prosthetic valve is more accurately positioned. Guide devices promote positioning the prosthetic valve within a native aortic valve and, optionally, to center the prosthetic valve within the native heart valve. Prosthetic valves may include one or more cut-outs, openings or recesses configured to align with the conduction tissue so that the conduction tissue is not contacted in a way that would lead to higher incidents of complete heart block.

Abstract: Systems, devices and methods for removing a blood clot (10) from a blood vessel (12). Various uses of suction pressure and positive pressure, proximal and/or distal to the blood clot (10) assist with clot dislodgement and removal. The pressure(s) may be constant and/or cycled/pulsed to assist with clot dislodgement and/or removal. Various further devices assist with separating the clot (10) from the vessel (12).

Abstract: Devices, systems and methods to position a prosthetic heart valve such that the prosthetic valve is more accurately positioned. Guide devices promote positioning the prosthetic valve within a native aortic valve and, optionally, to center the prosthetic valve within the native heart valve. Prosthetic valves may include one or more cut-outs, openings or recesses configured to align with the conduction tissue so that the conduction tissue is not contacted in a way that would lead to higher incidents of complete heart block.

Abstract: Anchors and systems for docking a prosthetic heart valve at a native heart valve are disclosed. An anchor can include at least three coils and a seal positioned between at least two adjacent coils of the at least three coils. The seal circumscribes at least a portion of the at least two adjacent coils and has opposite ends that are spaced away from corresponding opposite ends of the at least three coils.

Abstract: A communications system for providing data communication to a vehicle (10), the communications system comprising: a mobile transport layer proxy (150) located on the vehicle; a parent transport layer proxy (170) located remote from the vehicle; the mobile transport layer proxy being configured to: accept a transport layer connection with a host device (32, 33), the transport layer connection being addressed to a remote server (160); and communicate with the parent transport layer proxy via multiple paths using a multipath transport layer protocol to communicate on behalf of the host device whilst identifying as the mobile transport layer proxy; and the parent transport layer proxy being configured to: communicate with the mobile transport layer proxy using the multipath transport layer protocol; and communicate with the remote server whilst identifying as the parent transport layer proxy to communicate on behalf of the mobile transport layer proxy to permit the host device to communicate with the remote serve

Abstract: Prosthetic heart valves and anchors for use with such valves are provided that allow for an improved implantation procedure. In various embodiments, an anchoring device is formed as a coiled or twisted anchor that includes one or more turns that twist or curve around a central axis. One or more arms attached to the frame of the valve guide the anchoring device into position at the native valve as it exits the delivery catheter, and the expandable prosthetic valve is held within the coil of the anchoring device. The anchoring device and the valve can be delivered together, simplifying the valve replacement procedure.

Abstract: Apparatus for treating blood flow regurgitation through a native heart valve (16) includes a selective occlusion device sized and configured to be implanted in the native heart valve (16) and selectively operating with at least one of the first or second native leaflets (16a, 16b) to allow blood flow through the native heart valve (16) when the heart cycle is in diastole and reduce blood flow regurgitation through the native heart valve (16) when the heart cycle is in systole. A clip structure (50) is coupled with the selective occlusion device. The clip structure (50) is configured to be affixed to a margin of at least one of the first or second native leaflets (16a, 16b) to secure the selective occlusion device to the native heart valve (16).

Abstract: Systems and methods for docking a heart valve prosthesis. A system can include an anchor formed as multiple coils adapted to support a heart valve prosthesis with coil portions positioned above and below the heart valve annulus. At least one of the coil portions can normally be at a first diameter and be expandable to a second, larger diameter upon application of radial outward force from within the helical anchor. Methods can include delivering an anchor, positioning and implanting a heart valve prosthesis, and expanding the heart valve prosthesis inside the anchor.

Abstract: Systems, devices and methods for removing a blood clot (10) from a blood vessel (12). Various uses of suction pressure and positive pressure, proximal and/or distal to the blood clot (10) assist with clot dislodgement and removal. The pressure(s) may be constant and/or cycled/pulsed to assist with clot dislodgement and/or removal. Various further devices assist with separating the clot (10) from the vessel (12).

Abstract: Apparatus for treating blood flow regurgitation through a native heart valve (16) includes a selective occlusion device sized and configured to be implanted in the native heart valve (16) and selectively operating with at least one of the first or second native leaflets (16a, 16b) to allow blood flow through the native heart valve (16) when the heart cycle is in diastole and reduce blood flow regurgitation through the native heart valve (16) when the heart cycle is in systole. A clip structure (50) is coupled with the selective occlusion device. The clip structure (50) is configured to be affixed to a margin of at least one of the first or second native leaflets (16a, 16b) to secure the selective occlusion device to the native heart valve (16).

Abstract: Prosthetic heart valves and anchors for use with such valves are provided that allow for an improved implantation procedure. In various embodiments, an anchoring device is formed as a coiled or twisted anchor that includes one or more turns that twist or curve around a central axis. One or more arms attached to the frame of the valve guide the anchoring device into position at the native valve as it exits the delivery catheter, and the expandable prosthetic valve is held within the coil of the anchoring device. The anchoring device and the valve can be delivered together, simplifying the valve replacement procedure.

Abstract: Apparatus for treating blood flow regurgitation through a native heart valve (16) includes a selective occlusion device sized and configured to be implanted in the native heart valve (16) and selectively operating with at least one of the first or second native leaflets (16a, 16b) to allow blood flow through the native heart valve (16) when the heart cycle is in diastole and reduce blood flow regurgitation through the native heart valve (16) when the heart cycle is in systole. A clip structure (50) is coupled with the selective occlusion device. The clip structure (50) is configured to be affixed to a margin of at least one of the first or second native leaflets (16a, 16b) to secure the selective occlusion device to the native heart valve (16).

Abstract: A mobile device comprising: a first transceiver configured to communicate with a plurality of base stations; a positioning unit configured to provide location information of the mobile device; the mobile device being configured to store connection criteria associated with a first base station of the plurality of base stations; and the mobile device being configured to, based on a location of the mobile device and the connection criteria, select the first base station of the plurality of base stations to communicate with, and initiate a connection with the first base station.

Abstract: Devices, systems and methods to position a prosthetic heart valve such that the prosthetic valve is more accurately positioned. Guide devices promote positioning the prosthetic valve within a native aortic valve and, optionally, to center the prosthetic valve within the native heart valve. Prosthetic valves may include one or more cut-outs, openings or recesses configured to align with the conduction tissue so that the conduction tissue is not contacted in a way that would lead to higher incidents of complete heart block.