Abstract: A system includes a polymer bag, a fluid network, a saturation block, and a wick. The polymer bag has a sealed envelope and a fitment. The fluid network is coupled to the fitment. The saturation block has a fluid inlet coupled to the fluid network and has a wick chamber. The wick is configured for disposition in the wick chamber.

Abstract: A system is described for interchange of problems and solutions by a human or computer which system has the capability to use market forces to determine a price of the solutions. The system comprises a client subsystem for solving problems, a client subsystem for submitting problems, an API by which to access the centralized exchange system, data storage, an administration subsystem, and a primary processing subsystem.

Abstract: The tool unit for the ultrasonically assisted rotary machining of a workpiece comprises a converter (23) including at least one electroacoustic transducer (22) for generating and transmitting ultrasonic oscillations, a tool (30) that is coupled to the converter, and a holder (21) in which the converter including the transducer is arranged and which is insertable at least partially in the retainer (11) of a tool spindle (10) and connectable thereto by means of a detachable connection (27).

Abstract: The tool unit for the ultrasonically assisted rotary machining of a workpiece comprises a converter (23) including at least one electroacoustic transducer (22) for generating and transmitting ultrasonic oscillations, a tool (30) that is coupled to the converter, and a holder (21) in which the converter including the transducer is arranged and which is insertable at least partially in the retainer (11) of a tool spindle (10) and connectable thereto by means of a detachable connection (27).

Abstract: The dicarboxylic, heterocyclic and substituted benzoic acid alkylene bridged piperidyl amides and esters are serotonin M antagonists.

Abstract: A diagnostic display system for indicating the status of elevator system operating conditions develops signals representing each operating condition and detects when a car is delayed in responding to a request for service. Signals representing each operating condition are stored when a delayed car response is detected so that the status of the operating conditions as they were at the time of delayed car response can be displayed at a later time.

Abstract: The dicarboxylic, heterocyclic and substituted benzoic acid alkylene bridged piperidyl amides and esters are serotonin M antagonists.

Abstract: The dicarboxylic, heterocyclic and substituted benzoic acid alkylene bridged piperidyl amides and esters are serotonin M antagonists.

Abstract: This invention provides compounds of ##STR1## wherein R.sub.1 is benzyl or benzyl substituted by hydroxy, chlorine, fluorine, amino, amido, (C.sub.2-5) alkanoylamino, (C.sub.1-4) alkyl, (C.sub.1-4) alkylamino, (C.sub.1-4) alkoxy, (C.sub.1-4) alkylamido, di[(C.sub.1-4) alkyl]amino, or di[(C.sub.1-4) alkyl]amino,R.sub.2, R.sub.4 and R.sub.5 are each (C.sub.1-4) alkyl, andR.sub.3 is (C.sub.2-4) alkylare prolactin secretion promoters.

Abstract: The invention provides indole compounds useful for the treatment of hypertension, processes for the preparation of said compounds and pharmaceutical compositions containing these compounds.The compounds of the invention have the formula ##STR1## wherein n is 2 or 3, A is 1,4-cyclohexylidene or trimethylene and R.sub.1 is H or alkyl, or A together with NR.sub.1 is 4-piperidyl, R.sub.2 is hydrogen or alkyl, R.sub.3 is alkyl, cycloalkyl, amino, alkylamino, dialkylamino, phenylamino, unsubstituted or substituted phenyl or benzyl, pyridylmethyl or an heterocycle, R.sub.4 is hydrogen, chlorine, bromine or alkyl, R.sub.5 is hydrogen, alkyl, alkoxy or alkylthio, and X is --CO-- or --CS.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein X is hydrogen, chlorine or bromine,R.sub.1 is methyl or ethyl, andR.sub.2 is CH.sub.2 --CN, or a group NR.sub.3 R.sub.4, whereinR.sub.3 is hydrogen or alkyl of 1 to 4 carbon atoms, andR.sub.4 is SO.sub.2 R.sub.5, wherein R.sub.5 is alkyl of 1 to 4 carbon atoms, mono- to tri-halogenalkyl of 1 to 4 carbon atoms, phenyl, pyridyl, phenyl monosubstituted by halogen or alkoxy of 1 to 4 carbon atoms, or a group NR.sub.6 R.sub.7, wherein each ofR.sub.6 and R.sub.7 is independently hydrogen or alkyl of 1 to 4 carbon atoms, orR.sub.6 and R.sub.7 together are one of the groups (CH.sub.2).sub.n or (CH.sub.2).sub.2 --A--(CH.sub.2).sub.2, whereinn is a number from 3 to 7, andA is oxygen, sulphur or nitrogen substituted by alkyl of 1 to 4 carbon atoms or phenyl,useful as prolactin secretion agents and antiparkinson agents.

Abstract: The present invention provides compounds of formula I, ##STR1## wherein X is hydrogen, chlorine or bromine,R.sub.1 is methyl or ethyl,R.sub.2 is alkyl of 1 to 4 carbon atoms or allyl,R.sub.3 is CH.sub.2 CN or a group --NR.sub.4 R.sub.5, wherein R.sub.4 is hydrogen or alkyl of 1 to 4 carbon atoms, and R.sub.5 is alkanoyl of 1 to 5 carbon atoms, alkoxycarbonyl of 2 to 5 carbon atoms in the aggregate thereof, or mono-, di- or tri-haloalkoxycarbonyl of 3 to 5 carbon atoms, wherein the alkoxy group is substituted by halogen other than in the .alpha. position to the oxygen atom, or R.sub.5 is SO.sub.2 R.sub.6, wherein R.sub.6 is alkyl of 1 to 4 carbon atoms, mono-, di- or tri-haloalkyl of 1 to 4 carbon atoms, phenyl, phenyl mono-substituted by halogen or alkoxy of 1 to 4 carbon atoms, or pyridyl, or R.sub.6 is a group NR.sub.7 R.sub.8, wherein R.sub.7 and R.sub.8 are, independently, hydrogen or alkyl of 1 to 4 carbon atoms, or R.sub.7 and R.sub.8 together form --[CH.sub.2 ].sub.n -- or --[CH.sub.2 ].sub.2 --A--[CH.

Abstract: The present invention provides compounds of formula I, ##STR1## wherein X is hydrogen, chlorine or bromine andY is hydrogen or bromine, with the proviso that when X is chlorine Y is hydrogen,Z is carbonyl or sulphonyl,R.sub.1 is alkyl of 1 to 4 carbon atoms, andeither (i)R.sub.2 is hydrogen or alkyl of 1 to 5 carbon atoms, andR.sub.3 is hydrogen, alkyl of 1 to 5 carbon atoms, or phenyl,or (ii)R.sub.2 together with R.sub.3 is a radical of formula ##STR2## wherein R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are, independently, hydrogen or alkyl of 1 to 4 carbon atoms,or (iii)R.sub.2 together with R.sub.4 is a radical of formula--(CH.sub.2).sub.2 --A--(CH.sub.2).sub.2 --wherein A is a bond, oxygen, sulphur or NR.sub.8 wherein R.sub.8 is hydrogen, alkyl of 1 to 4 carbon atoms, phenyl or alkoxyphenyl,useful as venotonising agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R is branched chain alkyl of 3 to 6 carbon atoms, useful as venoconstrictors and venotonics.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein R.sub.1 is alkyl or 2 to 5 carbon atoms, andR.sub.2 is methyl or ethyl,useful as anti-migraine agents and for the treatment of orthostatic disorders.

Abstract: The present invention provides compounds of formula I, ##STR1## wherein X is hydrogen, chlorine or bromine andY is hydrogen or bromine, with the proviso that when X is chlorine Y is hydrogen,Z is carbonyl or sulphonyl,R.sub.1 is alkyl of 1 to 4 carbon atoms, andeither (i)R.sub.2 is hydrogen or alkyl of 1 to 5 carbon atoms, andR.sub.3 is hydrogen, alkyl of 1 to 5 carbon atoms, or phenyl,or (ii)R.sub.2 together with R.sub.3 is a radical of formula ##STR2## wherein R.sub.4, R.sub.5, R.sub.6 and R.sub.7 are, independently, hydrogen or alkyl of 1 to 4 carbon atoms,or (iii)R.sub.2 together with R.sub.4 is a radical of formula--(CH.sub.2).sub.2 --A--(CH.sub.2).sub.2 --wherein A is a bond, oxygen, sulphur or NR.sub.8 wherein R.sub.8 is hydrogen, alkyl of 1 to 4 carbon atoms, phenyl or alkoxyphenyl,useful as venotonising agents.

Abstract: This invention provides new compounds of formula I, ##STR1## wherein X Y IS THE GROUP ##STR2## and R is hydrogen, cyano, a 5- or 6-membered unsaturated heterocyclic radical attached through a ring carbon atom and having 1, 2 or 3 hetero ring atoms, the first hetero atom being nitrogen, oxygen or sulphur, and the second and third hetero atoms, if present, being nitrogen, or 2- or 4-pyridyl monosubstituted by lower alkyl, lower alkoxy or halogen,Useful as anti-Parkinson agents.

Abstract: The present invention provides compounds of the formula, ##STR1## wherein R.sub.1 is alkyl (C.sub.1-5),R.sub.2 is alkyl (C.sub.1-5),R.sub.3 is hydrogen or halogen, and either each of R.sub.4 and R.sub.5 is hydrogen, orR.sub.4 and R.sub.5, together, are a bond,Which are useful as sleep-inducing and sleep-prolonging agents.

Abstract: The present invention provides a novel cyclization process useful for the production of the peptide moiety of an ergotalkaloid.

Abstract: Compounds of formula I, ##STR1## wherein R.sub.1 is alkyl of 1 to 4 carbon atoms,R.sub.2 is hydrogen, alkyl of 1 to 4 carbon atoms or benzyl,R.sub.3 and R.sub.5 are, independently, hydrogen or methyl,R.sub.4 is hydrogen or alkyl of 1 to 4 carbon atoms, andR.sub.6 and R.sub.7 together form a single bond, orR.sub.6 and R.sub.7 are each hydrogen,R.sub.6 is methoxy, andR.sub.7 is hydrogen,Are useful in the treatment of hypertension, angina pectoris, depressions, neuroses and psychoses.