Abstract: A physiological monitoring system may use photonic signals at one or more wavelengths to determine physiological parameters. The system may receive a photoplethysmograph signal, and generated a difference signal based on the photoplethysmograph signal. The system may specify a segment of the photoplethysmograph signal and a segment of the difference signal. The system may associate each value of the segment of the photoplethysmograph signal to a corresponding value of the segment of the difference signal to generate associated value pairs. The system may compare the associated value pairs to a reference characteristic, and determine a signal quality metric based on the comparison.

Abstract: A physiological monitoring system may use photonic signals at one or more wavelengths to determine physiological parameters. During monitoring, a physiological sensor may become improperly positioned, which may affect the physiological attenuation of the photonic signals, and accordingly a detected light signal. The detected light signal may include an ambient light component and a signal component corresponding to the one or more wavelengths of light. The physiological monitoring system may determine a reference characteristic based on the ambient light component, and compare the signal component with the ambient light component to determine a sensor-off condition.

Abstract: A physiological monitoring system may determine a probe-off condition. A physiological sensor may be used to emit one or more wavelengths of light. A received light signal may be processed to obtain a light signal corresponding to the emitted light and an ambient signal. The signals may be analyzed to identify similar behavior. The system may determine whether the physiological sensor is properly positioned based on the analysis.

Abstract: A physiological monitoring system may use photonic signals at one or more wavelengths to determine physiological parameters. During monitoring, a physiological sensor may become improperly positioned, which may affect the physiological attenuation of the photonic signals, and accordingly a detected light signal. The detected light signal may include an ambient light component and a signal component corresponding to the one or more wavelengths of light. One or both components may exhibit an interference signal component caused by environmental light. The physiological monitoring system may analyze the interference signal components to determine a sensor-off condition.

Abstract: According to embodiments, techniques for using continuous wavelet transforms and spectral transforms to determine oxygen saturation from photoplethysmographic (PPG) signals are disclosed. According to embodiments, a first oxygen saturation may be determined from wavelet transformed PPG signals and a second oxygen saturation may be determined from spectral transformed PPG signals. An optimal oxygen saturation may be determined by selecting one of the first and the second oxygen saturation or by combining the first and the second oxygen saturation. According to embodiments, a spectral transform of PPG signals may be performed to identify a frequency region associated with a pulse rate of the PPG signal. A continuous wavelet transform of the PPG signals at a scale corresponding to the identified frequency region may be performed to determine oxygen saturation from the wavelet transformed signal.

Abstract: One or more physiological conditions of a patient can be observed by obtaining a photoplethysmograph (“PPG”) signal from the patient and by only lightly filtering that signal. The light filtering of the PPG may be such as to only remove (for example) high frequency noise from that signal, while leaving in the signal most or all frequency components that are due to physiological events in the patient. In this way, such physiological events can be observed via a visual display of the lightly filtered PPG signal and/or via other signal processing of the lightly filtered PPG signal to automatically extract certain physiological parameters or characteristics from that signal.

Abstract: According to embodiments, techniques for detecting probe-off events are disclosed. A sensor or probe may be used to obtain a plethysmograph or photoplethysmograph (PPG) signal from a subject. A wavelet transform of the signal may be performed and a scalogram may be generated based at least in part on the wavelet transform. One or more characteristics of the scalogram may be determined. The determined characteristics may include, for example, an energy decrease, a broadscale high-energy cone, a regular, repeated high-scale pattern, a low-scale information pattern; and a pulse band. The absence or presence of these and other characteristics, along with information about the characteristics, may be analyzed to detect a probe-off event. A confidence indicator may be calculated in connection with probe-off event detections and alarms may be generated when probe-off events occur.

Abstract: Methods and systems are disclosed for analyzing multiple scale bands in the scalogram of a physiological signal in order to obtain information about a physiological process. An analysis may be performed to identify multiple scale bands that are likely to contain the information sought. Each scale band may be assessed to determine a band quality, and multiple bands may be combined based on the band quality. Information about a physiological process may determined based on the combined band. In an embodiment, analyzing multiple scale bands in a scalogram arising from a wavelet transformation of a photoplethysmograph signal may yield clinically relevant information about, among other things, the blood oxygen saturation of a patient.

Abstract: According to embodiments, techniques for using continuous wavelet transforms to process pulses from a photoplethysmographic (PPG) signal are disclosed. The continuous wavelet transform of the PPG signal may be used to identify and characterize features and their periodicities within a signal. Regions, phases and amplitudes within the scalogram associated with these features may then be analyzed to identify, locate, and characterize a true pulse within the PPG signal. Having characterized and located the pulse in the PPG (possibly also using information gained from conventional pulse processing techniques such as, for example, by identifying turning points for candidate pulse maxima and minima on the PPG, frequency peak picking for candidate scales of pulses, etc.), the PPG may be parameterized for ease of future processing.

Abstract: A sensor system is provided for determining a pulse transit time measurement of a patient. The sensor system includes a carotid sensor device configured to be positioned on a neck of the patient over a carotid artery of the patient. The carotid sensor device is configured to detect a plethysmograph waveform from the carotid artery. The sensor system includes a temporal sensor device that is operatively connected to the carotid sensor device. The temporal sensor device is configured to be positioned on the patient over a temporal artery of the patient. The temporal sensor device is configured to detect a plethysmograph waveform from the temporal artery.

Abstract: A PPG system for determining a stroke volume of a patient includes a PPG sensor configured to be secured to an anatomical portion of the patient. The PPG sensor is configured to sense a physiological characteristic of the patient. The PPG system may include a monitor operatively connected to the PPG sensor. The monitor receives a PPG signal from the PPG sensor. The monitor includes a pulse trending module determining a slope transit time of an upslope of a primary peak of the PPG signal. The pulse trending module determines a stroke volume of the patient as a function of the slope transit time.

Abstract: Methods and systems are provided that allow for the simultaneous calculation of pulse and regional blood oxygen saturation. An oximeter system that includes a sensor with a plurality of emitters and detectors may be used to calculate a pulse and/or regional blood oxygen saturation. A plurality of light signals may be emitted from light emitters. A first light signal may be received at a first light detector and a second light signal may be received at a second light detector. A pulse and/or regional blood oxygen saturation value may be calculated based on the received first and/or second light signals. The pulse and regional blood oxygen saturation values may be calculated substantially simultaneously. The calculated pulse and regional blood oxygen saturation values as well as other blood oxygen saturation values may be displayed simultaneously in a preconfigured portion of a display.

Abstract: A system for determining stroke volume of an individual. The system includes a skew-determining module that is configured to calculate a first derivative of photoplethysmogram (PPG) signals of the individual. The first derivative forms a derivative waveform. The skew-determining module is configured to determine a skew metric of the first derivative, wherein the skew metric is indicative of a morphology of at least one pulse wave detected from blood flow of the individual in the derivative waveform. The system also includes an analysis module that is configured to determine a stroke volume of the individual. The stroke volume is a function of the skew metric of the first derivative.

Abstract: A system is configured to determine cardiac output of a patient. The system may include a first sub-system configured to detect a first physiological signal, and a second sub-system configured to detect a second physiological signal that differs from the first physiological signal. The first and second sub-systems may be separate and distinct from one another. The system may also include a cardiac output determination module that is configured to determine the cardiac output based, at least in part, on the first and second physiological signals.

Abstract: A system to determine a resting heart rate (HR) of an individual. The system may include a monitor that is configured to be operatively connected to a sensor that obtains physiological signals from an individual. The monitor is configured to receive the physiological signals from the sensor. The monitor may include a validation module that is configured to analyze the physiological signals to identify valid heart beats from the physiological signals. The monitor may also include a rate-determining module that is configured to determine an HR signal that is based on the valid heart beats. The HR signal includes a series of data points. The monitor may also include an analysis module that is configured to analyze the HR signal and identify baseline data points from the series of data points. The analysis module is configured to calculate the resting HR based on the baseline data points.

Abstract: A system is configured to determine a fluid responsiveness index of a patient from a physiological signal. The system may include a sensor configured to be secured to an anatomical portion of the patient, and a monitor operatively connected to the sensor. The sensor is configured to sense a physiological characteristic of the patient. The monitor is configured to receive a physiological signal from the sensor. The monitor may include an index-determining module configured to determine the fluid responsiveness index through formation of a ratio of one or both of amplitude or frequency modulation of the physiological signal to baseline modulation of the physiological signal.

Abstract: According to embodiments, systems and methods for detecting the occurrence of events from a signal are provided. A signal processing system may analyze baseline changes and changes in signal characteristics to detect events from a signal. The system may also detect events by analyzing energy parameters and artifacts in a scalogram of the signal. Further, the system may detect events by analyzing both the signal and its corresponding scalogram.

Abstract: The present disclosure relates to signal processing systems and methods, and more particularly, to systems and methods for analyzing multiparameter spaces to determine changes in a physiological state. In embodiments, a first signal and a second signal may be obtained, from which a first plurality of values of a physiological parameter may be determined. At least one of the signals also may be used to generate a scalogram derived at least in part from the signal. A second plurality of values may be determined based at least in part on a feature in the scalogram. The first and second plurality of values may then be associated, and a physiological state may be analyzed using the associated first and second values. In an embodiment, the signals may be PPG signals and the associated first and second values may include a parameter scatter plot that may permit a user to determine changes in a patient's ventilation state over time.

Abstract: Methods and systems are disclosed for analyzing multiple scale bands in the scalogram of a physiological signal in order to obtain information about a physiological process. An analysis may be performed to identify multiple scale bands that are likely to contain the information sought. Each scale band may be assessed to determine a band quality, and multiple bands may be combined based on the band quality. Information about a physiological process may determined based on the combined band. In an embodiment, analyzing multiple scale bands in a scalogram arising from a wavelet transformation of a photoplethysmograph signal may yield clinically relevant information about, among other things, the blood oxygen saturation of a patient.

Abstract: According to embodiments, systems, devices, and methods for ridge selection in scalograms are disclosed. Ridges or ridge components are features within a scalogram which may be computed from a signal such as a physiological (e.g., photoplethysmographic) signal. Ridges may be identified from one or more scalograms of the signal. Parameters characterizing these ridges may be determined. Based at least in part on these parameters, a ridge density distribution function is determined. A ridge is selected from analyzing this ridge density distribution function. In some embodiments, the selected ridge is used to determine a physiological parameter such as respiration rate.