Patents by Inventor Paul Stanley Bury

Paul Stanley Bury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of a boron-substituted porphyrin
    Patent number: 8680265
    Abstract: Processes are disclosed for the preparation of a compound having the formula: (I) and intermediate compounds wherein M is a single-photon-emission tomography imageable radiometal and/or a paramagnetic metal, R is hydrogen or a halogen provided that at least one R is halogen and Y is selected from ortho, meta or para O(CH2)nC2HB9H10 or O(CH2)nC2HB10H10 wherein n is 0 or an integer from 1 to 20 and O(CH2)nC2HB9H10 is nido ortho-, meta- or para-carborane and O(CH2)nC2HB10H10 is ortho-, meta- or para-carborane.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: March 25, 2014
    Assignee: PSIMEI Pharmaceuticals
    Inventors: Paul Stanley Bury, Ke-Dong Li, Anthony David Bentham, Bipin Chandra Muljibhai Patel
  • PROCESS FOR THE PREPARATION OF A BORON-SUBSTITUTED PORPHYRIN
    Publication number: 20100016613
    Abstract: Processes are disclosed for the preparation of a compound having the formula: (I) and intermediate compounds wherein M is a single-photon-emission tomography imageable radiometal and/or a paramagnetic metal, R is hydrogen or a halogen provided that at least one R is halogen and Y is selected from ortho, meta or para O(CH2)nC2HB9H10 or O(CH2)nC2HB10H10 wherein n is 0 or an integer from 1 to 20 and O(CH2)nC2HB9H10 is nido ortho-, meta- or para-carborane and O(CH2)nC2HB10H10 is ortho-, meta- or para-carborane.
    Type: Application
    Filed: December 13, 2005
    Publication date: January 21, 2010
    Applicant: PSIMEI PHARMACEUTICALS PLC
    Inventors: Paul Stanley Bury, Ke-Dong Li, Anthony David Bentham, Bipin Chandra Muljibhai Patel
  • Compounds, their preparation and use
    Patent number: 7220877
    Abstract: A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: May 22, 2007
    Assignee: Novo Nordisk A/S
    Inventors: Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, John Patrick Mogensen
  • Combination therapy using a dual PPAR-?/PPAR-? activator and a GLP-1 derivative for the treatment of metabolic syndrome and related diseases and disorders
    Patent number: 7202213
    Abstract: The present invention relates to a pharmaceutical composition comprising a dual Peroxisome Proliferator-Activated Receptor-alpha/Peroxisome Proliferator-Activated Receptor-gama activator (PPAR-?/PPAR-?) and a Glucagon Like Peptide-1 (GLP-1) derivative for treating, preventing and reducing the risk of developing Type 2 diabetes, insulin resistance, dyslipidemia, obesity, hypertension and other related diseases and disorders.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: April 10, 2007
    Assignee: Novo Nordisk A/S
    Inventors: John Patrick Mogensen, Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, Ingrid Pettersson
  • Compounds, their preparation and use
    Patent number: 7067530
    Abstract: Novel compounds of general formula (I), the use of these compounds as medicaments, pharmaceuticaly compositions comprising the compounds and methods of treatment employing these compounds and compostiones. The present compounds may be useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR). The compounds exert their effects by modulating the PPAR? response in a partial agonist manner.
    Type: Grant
    Filed: July 29, 2002
    Date of Patent: June 27, 2006
    Assignee: Novo Nordisk A/S
    Inventors: Lone Jeppesen, Paul Stanley Bury, John Patrick Mogensen, Ingrid Pettersson, Per Sauerberg
  • Compounds, their preparation and use
    Patent number: 6972294
    Abstract: Disclosed are novel compounds of formula (I) wherein A1, A2, Ar, R5, R6, R8, M, Q, Y, Z, k, m and n are as defined in the specification. These compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR). Such conditions include diabetes and obesity.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: December 6, 2005
    Assignee: Novo Nordisk, A/S
    Inventors: Anthony Murray, Per Sauerberg, Lone Jeppesen, Ingrid Pettersson, Paul Stanley Bury
  • Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives
    Patent number: 6869967
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPAR? suptype.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: March 22, 2005
    Assignee: Novo Nordisk A/S
    Inventors: Lone Jeppesen, Paul Stanley Bury, John Patrick Mogensen, Ingrid Pettersson, Per Sauerberg
  • Compounds, their preparation and use
    Patent number: 6867218
    Abstract: The present invention relates to compounds of the general formula (I) The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: February 20, 2003
    Date of Patent: March 15, 2005
    Assignee: Novo Nordisk A/S
    Inventors: John Patrick Mogensen, Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, Ingrid Pettersson
  • Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
    Publication number: 20040229899
    Abstract: The present invention relates to compounds of formula (I) 1
    Type: Application
    Filed: January 6, 2004
    Publication date: November 18, 2004
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
    Patent number: 6723731
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, Ar, X, Q, A, Y and Z are as defined in the specification. These compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: April 20, 2004
    Assignees: Novo Nordisk A/S, Dr. Reddy's Research Foundation
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Compounds, their preparation and use
    Patent number: 6703401
    Abstract: The present invention relates to compounds of the general formula (I) The compounds are useful in the treatment and/or prevention of conditions mediated by clear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: November 27, 2001
    Date of Patent: March 9, 2004
    Assignees: Novo Nordisk A/S, Dr. Reddy's Research Foundation
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Compounds, their preparation and use
    Patent number: 6683111
    Abstract: The present invention relates to compounds of the general formula (I) The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: January 27, 2004
    Assignees: Novo Nordisk A/S, Dr. Reddy's Research Foundation
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Combination therapy using a dual PPAR-a/PPAR-y activator and a GLP-1 derivative for the treatment of metabolic syndrome and related diseases and disorders
    Publication number: 20030199451
    Abstract: The present invention relates to a pharmaceutical composition comprising a dual Peroxisome Proliferator-Activated Receptor-alpha/Peroxisome Proliferator-Activated Receptor-gama activator (PPAR-&agr;/PPAR-&ggr;) and a Glucagon Like Peptide-1 (GLP-1) derivative for treating, preventing and reducing the risk of developing Type 2 diabetes, insulin resistance, dyslipidemia, obesity, hypertension and other related diseases and disorders.
    Type: Application
    Filed: May 20, 2003
    Publication date: October 23, 2003
    Inventors: John Patrick Mogensen, Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, Ingrid Pettersson
  • Compounds, their preparation and use
    Publication number: 20030195200
    Abstract: The present invention relates to compounds of the general formula (I) 1
    Type: Application
    Filed: February 20, 2003
    Publication date: October 16, 2003
    Inventors: John Patrick Mogensen, Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, Ingrid Pettersson
  • New compounds, their preparation and use
    Publication number: 20030171358
    Abstract: The present invention relates to compounds of the general formula (I) 1
    Type: Application
    Filed: January 27, 2003
    Publication date: September 11, 2003
    Inventors: Lone Jeppesen, Per Sauerberg, Anthony Murray, Paul Stanley Bury
  • Compounds useful in the treatment of conditions mediated by peroxisome proliferator-activated receptors (PPAR)
    Patent number: 6602901
    Abstract: The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, Ar, X, Q, A, Y and Z are as defined in the specification. These compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: April 13, 2001
    Date of Patent: August 5, 2003
    Assignee: Novo Nordisk A/S
    Inventors: Lone Jeppesen, Paul Stanley Bury, Per Sauerberg
  • Novel compounds, their preparation and use
    Publication number: 20030139473
    Abstract: Novel compounds of the general formula (I), the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR), in particular the PPAR&dgr; suptype.
    Type: Application
    Filed: July 19, 2002
    Publication date: July 24, 2003
    Inventors: Lone Jeppesen, Paul Stanley Bury, John Patrick Mogensen, Ingrid Pettersson, Per Sauerberg
  • Novel compounds, their preparation and use
    Publication number: 20030109560
    Abstract: Novel compounds of general formula (I), the use of these compounds as medicaments, pharmaceuticaly compositions comprising the compounds and methods of treatment employing these compounds and compostiones. The present compounds may be useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR). The compounds exert their effects by modulating the PPAR&ggr; response in a partial agonist manner.
    Type: Application
    Filed: July 29, 2002
    Publication date: June 12, 2003
    Inventors: Lone Jeppesen, Paul Stanley Bury, John Patrick Mogensen, Ingrid Pettersson, Per Sauerberg
  • Novel compounds, their preparation and use
    Publication number: 20030109579
    Abstract: A novel class of dicarboxylic acid derivatives, the use of these compounds as pharmaceutical compositions, pharmaceutical compositions comprising the compounds and methods of treatment employing these compounds and compositions. The present compounds may be useful in the treatment and/or prevention of conditions mediated by Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Application
    Filed: October 16, 2002
    Publication date: June 12, 2003
    Inventors: Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, John Patrick Mogensen
  • Alkynyl-substituted propionic acid derivatives, their preparation and use
    Patent number: 6569901
    Abstract: The present invention relates to compounds of formula (I) The compounds are useful in the treatment and/or prevention of conditions mediated by nuclear receptors, in particular the Peroxisome Proliferator-Activated Receptors (PPAR).
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: May 27, 2003
    Assignee: Novo Nordisk A/S
    Inventors: John Patrick Mogensen, Per Sauerberg, Paul Stanley Bury, Lone Jeppesen, Ingrid Pettersson