Abstract: A method and device for treatment of a varicose vein is provided which includes the step of applying to the skin of a subject superficial to the vein to be treated a device including: (a) an element for securing the device to the leg of a subject superficial to the vein to be treated such as a carrier tape; and (b) a one-way valve element such as a cantilever element biased by a spring for applying a selected amount of pressure to the skin superficial to the vein to be treated in a manner such that blood-flow toward the heart is permitted during peripheral venous pumping but wherein backflow away from the heart as a result of gravity is substantially reduced; and applying sufficient pressure to the skin superficial to the vein to be treated in a manner such that blood-flow toward the heart is permitted during peripheral venous pumping but wherein backflow away from the heart as a result of gravity is substantially reduced.