Patents by Inventor Paul Stauffer

Paul Stauffer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250137734
    Abstract: System for cooling and/or heating at least one medium, comprising: a first heat exchanger comprising a first outer end and a second outer end, wherein the second outer end is closed, wherein the first heat exchanger is configured to receive a phase change material; a force unit configured to be fluidly connected to the first outer end of the first heat exchanger and configured to compress the phase change material in the first heat exchanger; a PCM accumulator configured to receive phase change material; and a control unit configured to: during compression of the phase change material in the first heat exchanger by the force unit, fluidly disconnect the PCM accumulator from the first heat exchanger; and during expansion of the phase change material in the first heat exchanger, fluidly connect the PCM accumulator with the first heat exchanger for allowing phase change material to expand into the PCM accumulator.
    Type: Application
    Filed: October 19, 2022
    Publication date: May 1, 2025
    Inventors: Heinrich Paul STAUFFER, Juan Enrique STAUFFER, Rodrigo Ignacio SLIVA BRAVO
  • Publication number: 20240181274
    Abstract: A device having a biocompatible polymer as a body and regularly spaced radiation seeds and regularly spaced magnetic materials disposed of within the body of the biocompatible polymer, or uniformly distributed liquid radiation and magnetic fluid materials within a polymer slab, hollow thick wall polymer shell, or thin wall polymer balloon, as suitable for surgical placement within a resection cavity for treatment of at-risk tissue in the tumor margin with local hyperthermia in combination with radiation and potentially also with chemotherapy and/or immunotherapy that is slowly released from the biocompatible polymer.
    Type: Application
    Filed: January 18, 2024
    Publication date: June 6, 2024
    Inventors: Paul Stauffer, Voichita Bar-ad, Mark Hurwitz, Adam Luginbuhl, Michele Marcolongo, Dario Rodrigues, David Cognetti, Joseph Curry, Katsiaryna Prudnikova
  • Patent number: 11911631
    Abstract: A device having a biocompatible polymer as a body and regularly spaced radiation seeds and regularly spaced magnetic materials disposed of within the body of the biocompatible polymer, or uniformly distributed liquid radiation and magnetic fluid materials within a polymer slab, hollow thick wall polymer shell, or thin wall polymer balloon, as suitable for surgical placement within a resection cavity for treatment of at-risk tissue in the tumor margin with local hyperthermia in combination with radiation and potentially also with chemotherapy and/or immunotherapy that is slowly released from the biocompatible polymer.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: February 27, 2024
    Assignees: Thomas Jefferson University, Drexel University
    Inventors: Paul Stauffer, Voichita Bar-ad, Mark Hurwitz, Adam Luginbuhl, Michele Marcolongo, Dario Rodrigues, David Cognetti, Joseph Curry, Katsiaryna Prudnikova
  • Publication number: 20220107143
    Abstract: The invention relates to a method for transferring heat between to or more media, which can be used for domestic, commercial or industrial purposes, subject only to the existence of temperature difference and to pressure variations. The invention also relates to a system for transferring heat.
    Type: Application
    Filed: October 20, 2021
    Publication date: April 7, 2022
    Applicant: Energy Innovation Systems Limited
    Inventors: Jean Baptiste Claudio SANTANDER KUBORN, Heinrich Paul STAUFFER, Rodrigo Ignacio SILVA BRAVO
  • Publication number: 20190099618
    Abstract: A device having a biocompatible polymer as a body and regularly spaced radiation seeds and regularly spaced magnetic materials disposed of within the body of the biocompatible polymer, or uniformly distributed liquid radiation and magnetic fluid materials within a polymer slab, hollow thick wall polymer shell, or thin wall polymer balloon, as suitable for surgical placement within a resection cavity for treatment of at-risk tissue in the tumor margin with local hyperthermia in combination with radiation and potentially also with chemotherapy and/or immunotherapy that is slowly released from the biocompatible polymer.
    Type: Application
    Filed: March 31, 2017
    Publication date: April 4, 2019
    Inventors: Paul Stauffer, Voichita Bar-ad, Mark Hurwitz, Adam Luginbuhl, Michele Marcolongo, Dario Rodrigues, David Cognetti, Joseph Curry, Katsiaryna Prudnikova
  • Publication number: 20050251235
    Abstract: A combination applicator is able to deliver heat and radiation, either simultaneously or sequentially, for the treatment of cancer or other disease. The combination applicator is flexible and able to conform to contoured anatomy of the patient. The combination applicator comprises a flexible, dielectric containing compartment having a tissue-engaging surface and an opposite, non-tissue-engaging surface. A heating surface comprising one or more RF or microwave antennas or ultrasound transducers is supported adjacent to the non-tissue-engaging surface. In addition, a plurality of conduits are also supported on the dielectric containing compartment, the conduits being adapted to communicate with at least one brachytherapy source. Additional conduits may be located on the tissue contacting surface of the dielectric containing compartment to accommodate moving or stationary temperature monitoring sensors.
    Type: Application
    Filed: March 30, 2005
    Publication date: November 10, 2005
    Inventors: Jaime Schlorff, Paul Stauffer
  • Patent number: 5636632
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultra sound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: March 9, 1994
    Date of Patent: June 10, 1997
    Assignees: Cygnus, Inc., The Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn
  • Patent number: 5323769
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: August 2, 1993
    Date of Patent: June 28, 1994
    Assignees: Cygnus Therapeutic Systems, The Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn
  • Patent number: 5231975
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: March 2, 1992
    Date of Patent: August 3, 1993
    Assignees: Cygnus Therapeutic Systems, Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn
  • Patent number: 5115805
    Abstract: A method for enhancing the permeability of the skin or other biological membrane to a material such as a drug is disclosed. In the method, the drug is delivered in conjunction with ultrasound having a frequency of above about 10 MHz. The method may also be used in conjunction with chemical permeation enhancers and/or with iontophoresis.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: May 26, 1992
    Assignees: Cygnus Therapeutic Systems, The Regents of the University of California
    Inventors: Durairaj Bommannan, Hirohisa Okuyama, Richard H. Guy, Paul Stauffer, Gordon L. Flynn