Abstract: Systems, method and computer readable medium are provided for automated storage and retrieval. User authentication information is received via a user interface for a dynamic storage and retrieval device. The user identity is verified based upon the authentication information and previously stored authentication data. Order information is retrieved for an order associated with the user following the verifying of user identity, the order information indicating one or more locations for items associated with the order. Instructions are transmitted to initiate a physical opening of at least one of the dynamic storage and retrieval device and at least one static storage location to enable the user to retrieve at least one item of the order, the static storage location including a controller controlling a locking mechanism and communicatively coupled to the dynamic storage and retrieval device.

Abstract: A transseptal puncture system and method uses a guiding instrument, and an atraumatic puncture instrument longitudinally movable therein, with a first electrode configured for ablation and a second electrode electrically insulated from the first electrode. An impedance monitoring module is configured to measure at least an impedance at the second electrode, and an electrical generator is configured to selectively apply electrical energy to the first electrode based at least in part on the measured impedance at the second electrode. Moreover, impedance measurements at the first and second electrodes are used to determine relative positions of the instruments in the approach, contact, ablation and puncture of the septum.

Abstract: An apparatus includes a body assembly, a shaft, and at least one tip member. The shaft extends distally from the body assembly and includes a distal end. The at least one tip member is secured at the distal end of the shaft. The at least one tip member and the distal end of the shaft are sized and configured to fit within a chamber of a heart of a human subject. The at least one tip member includes an atraumatic distal tip and an exterior dilation surface adjacent to the atraumatic distal tip. The atraumatic hollow distal tip may present an angled profile to minimize risk of coring tissue and is configured to deliver electrical energy to tissue for forming an opening through the tissue. The exterior dilation surface is configured to enlarge the opening formed by the atraumatic distal tip.

Abstract: An apparatus includes a body and a shaft assembly extending distally from the body. The shaft assembly includes a proximal portion defining a longitudinal axis, a steerable portion distal to the proximal portion, and a distal portion distal to the steerable portion. The steerable portion is operable to drive the distal portion laterally away from and toward the longitudinal axis. The shaft assembly further includes at least one flex circuit assembly. The at least one flex circuit assembly includes a first navigation sensor configured to measure impedance signals that indicate a real-time position of the steerable portion. The at least one flex circuit assembly further includes a second navigation sensor configured to measure magnetic signals that indicate a real-time position of the steerable portion.

Abstract: The disclosed technology includes a catheter comprising an elongated deflectable element extending along a longitudinal axis from a proximal end to a distal end, a position electrode attached to the elongated deflectable element proximate the distal end and configured for impedance-based position tracking, and a covering at least partially enclosing the position electrode. The covering can comprise a plurality of apertures such that a portion of a conductive surface of the position electrode is exposed through each aperture of the plurality of apertures.

Abstract: A catheter including: an elongated body sized to traverse vasculature, defining a longitudinal axis, and including: an outer surface; and a proximal end and a distal end disposed on opposite sides thereof; an orientation lumen formed in the elongated body and defining a curved path extending proximally from the distal end towards the proximal end and about the longitudinal axis; an orientation insert disposed within the orientation lumen, the orientation insert including an oriented pull-wire attached to the distal end of the elongated body such that tightening the oriented pull-wire deflects the distal end to form a curve; and a flexible circuit disposed on the outer surface of the elongated body, the elongated body being substantially rotationally fixed about the longitudinal axis relative to the oriented pull-wire such that the flexible circuit is disposed toward an outer bend of the curve when the oriented pull-wire is tightened.

Abstract: A guiding sheath has a hemostatic valve and a central lumen into which a diagnostic or treatment catheter can be introduced and guided into a patient. The hemostatic valve also includes an electrically conducting element or proximity sensing element on its proximal end that interacts with a second electrically conducting element or proximity sensing element on a proximal end of the diagnostic or treatment catheter that can be passed through the central lumen of the guiding sheath and into the patient's heart. The interaction between the two electrically conducting elements or proximity sensing elements enables the location of the distal end of the diagnostic or treatment catheter in the patient's heart without the need for irradiating the patient.

Abstract: A catheter includes a catheter body and a distal tip section that includes an elongated member that extends along a longitudinal axis. An anchor mechanism can be disposed along an outer surface of the elongated member and/or within the elongated member in a first configuration. In a second configuration, the anchor mechanism can be configured to extend radially outward with respect to the longitudinal axis to surround at least a portion of the distal tip section.

Abstract: A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.

Abstract: A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.

Abstract: A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.