Abstract: The disclosed technology includes a medical probe. The medical probe includes an elongated body, a flexible circuit and one or more electrodes. The elongated body extends along a longitudinal axis from a proximal end to a distal end, defines a lumen, and includes a tube and outer wall jacket. The tube extends along the longitudinal axis and includes slits that permit the elongated body to deflect relative to the longitudinal axis. The outer wall jacket surrounds the tube. The flexible circuit is disposed on the outer wall jacket. The one or more electrodes are disposed on the flexible circuit and are designed to be placed in contact with tissue of an organ.

Abstract: A medical probe can comprise a tube comprising a proximal end and a distal end, the tube extending along a longitudinal axis. The medical probe can further comprise a plurality of spines disposed at the distal end of the tube, each spine of the plurality of spines comprising a first end that is fixed in relation to the tube and a second end that is unattached in relation to the tube. Each spine of the plurality of spines can be configured to transition between a collapsed configuration and an expanded configuration, the plurality of spines forming a basket when in the expanded configuration. The medical probe can further comprise a plurality of electrodes attached to the plurality of spines.

Abstract: The disclosed technology includes medical probe that includes an elongated shaft, a guidewire, coils, and electrodes. The elongated shaft extends along a longitudinal axis and is dimensioned to be inserted into a vein of Marshall. The guidewire extends through a lumen in the elongated shaft. The coils are connected to the distal dip of the elongated shaft and each coil is configured to generate a current when subjected to a magnetic field, the current being indicative of a position of the respective coil. The electrodes are connected to the distal tip. Each electrode is designed to (i) sense anatomical signals in the vein of Marshall and provide electrical signals which are indicative of the anatomical signals or (ii) convey ablation energy to a target tissue region proximal the vein of Marshall.

Abstract: The disclosed technology includes electrode attachments for a medical probe, including an electrode body configured to deliver electrical energy to biological tissues. Elongated member(s) of the medical probe can include one or more apertures, and the electrode(s) can include one or more electrode apertures to align with the apertures of the elongated member. A pin is placed into the aligned apertures to secure the electrode to the elongated member.

Abstract: A catheter includes a catheter body and a distal tip section that includes an elongated member that extends along a longitudinal axis. An anchor mechanism can be disposed along an outer surface of the elongated member and/or within the elongated member in a first configuration. In a second configuration, the anchor mechanism can be configured to extend radially outward with respect to the longitudinal axis to surround at least a portion of the distal tip section.

Abstract: A basket catheter having an end effector with multiple spines can be constructed with a combination of manufacturing techniques including at least two of the following techniques: individual spines, a loop with two spines, a cut sheet, and a cut tube. A cut sheet or a cut tube can be formed to include a distal hub that has openings through which spines of one or more additional structure can pass through so that the distal hub joins distinct structures of the end effector. This provides several alternative manufacturing techniques compared to those presently used in basket catheters which rely on only one of the aforementioned manufacturing techniques.

Abstract: The disclosed technology includes a medical end effector comprising one or more spines extending along a longitudinal axis. The spines further comprising a first surface being outward from the longitudinal axis; one or more contact pads affixed to a portion of the first surface of the spine; and one or more flexible circuits disposed over respective ones of the one or more contact pads, the one or more flexible circuits each comprising an electrode and an inductive coil as one unit.

Abstract: A sensor unit for a medical probe having coils that each have a respective central axis that is orthogonal to a longitudinal axis of the medical probe such that the coils are disposed one or more substrates. A first coil can have conductive surfaces exposed to an external environment while a second coil has its conductive surfaces insulated or sealed from the external environment. The coils can be configured to output 1) physiologic electrical signals (e.g., ECG) received at the at least two exposed windings, and 2) signals indicative of environmental impedance/conductance in the vicinity of the at least two exposed windings. The coils can further be configured to determine a position of the sensor based on magnetic field, determine a curvature of the sensor, directionally measure environmental impedance/conductance, and/or measure temperature.

Abstract: Examples presented herein illustrate various end effector designs with multiple spines that can expand from a collapsed configuration as the end effector traverses vasculature to an expanded configuration when the end effector is at a treatment site. In some examples, the end effector includes three frame loops which each include a pair of spines. At least one of the three frame-loops can have a bend at a distal end of the end effector so that the spines of the frame loop are not directly opposite each other with respect to the longitudinal axis. In some examples, the end effector includes an inner and an outer frame, each having multiple spines and configured such that one or both of the frames can rotate from an aligned configuration to an unaligned configuration.

Abstract: A sensor for a medical probe having one or more coils with at least two exposed winding portions. The one or more coils can be configured to output 1) electrocardiogram (ECG) signals received at the at least two exposed windings, and 2) signals indicative of environmental impedance/conductance in the vicinity of the at least two exposed windings. The one or more coils can further be configured to determine a position of the sensor based on magnetic field, determine a curvature of the sensor, directionally measure environmental impedance/conductance, and/or measure temperature. Insulated portions of the one or more coils can be interleaved with the at least two exposed winding portions. The sensor can be integral to a catheter or guide wire.

Abstract: The disclosed technology includes a medical probe comprising a tubular shaft having a proximal end and a distal end, the tubular shaft extending along a longitudinal axis. The medical probe further comprises an expandable basket assembly coupled to the distal end of the tubular shaft. The basket assembly includes a plurality of electrodes with each electrode of the plurality of electrodes having a lumen therethrough. The basket assembly further includes a plurality of spines extending along the longitudinal axis and configured to bow radially outward from the longitudinal axis when the expandable basket assembly is transitioned from a collapsed form to an expanded form. Each spine includes a proximal and a distal end and a strut passing through the lumen of an electrode. The strut includes a mechanical retainer disposed on the strut to prevent the electrode from sliding proximally or distally along a length of the spine.

Abstract: The disclosed technology includes a catheter comprising an elongated deflectable element extending along a longitudinal axis from a proximal end to a distal end, a position electrode attached to the elongated deflectable element proximate the distal end and configured for impedance-based position tracking, and a covering at least partially enclosing the position electrode. The covering can comprise a plurality of apertures such that a portion of a conductive surface of the position electrode is exposed through each aperture of the plurality of apertures.

Abstract: A catheter including: an elongated body sized to traverse vasculature, defining a longitudinal axis, and including: an outer surface; and a proximal end and a distal end disposed on opposite sides thereof; an orientation lumen formed in the elongated body and defining a curved path extending proximally from the distal end towards the proximal end and about the longitudinal axis; an orientation insert disposed within the orientation lumen, the orientation insert including an oriented pull-wire attached to the distal end of the elongated body such that tightening the oriented pull-wire deflects the distal end to form a curve; and a flexible circuit disposed on the outer surface of the elongated body, the elongated body being substantially rotationally fixed about the longitudinal axis relative to the oriented pull-wire such that the flexible circuit is disposed toward an outer bend of the curve when the oriented pull-wire is tightened.

Abstract: A guiding sheath has a hemostatic valve and a central lumen into which a diagnostic or treatment catheter can be introduced and guided into a patient. The hemostatic valve also includes an electrically conducting element or proximity sensing element on its proximal end that interacts with a second electrically conducting element or proximity sensing element on a proximal end of the diagnostic or treatment catheter that can be passed through the central lumen of the guiding sheath and into the patient's heart. The interaction between the two electrically conducting elements or proximity sensing elements enables the location of the distal end of the diagnostic or treatment catheter in the patient's heart without the need for irradiating the patient.

Abstract: A catheter includes a catheter body and a distal tip section that includes an elongated member that extends along a longitudinal axis. An anchor mechanism can be disposed along an outer surface of the elongated member and/or within the elongated member in a first configuration. In a second configuration, the anchor mechanism can be configured to extend radially outward with respect to the longitudinal axis to surround at least a portion of the distal tip section.

Abstract: A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.

Abstract: A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.

Abstract: A system and associated method for manipulating tissues and anatomical or other structures in medical applications for the purpose of treating diseases or disorders or other purposes. In one aspect, the system includes a delivery device configured to deploy and implant anchor devices for such purposes.