Abstract: A device for delivering a medicated product into a bodily cavity includes a barrel member having a dispensing end, a proximal end, which is positioned opposite the dispensing end, and a bore, which extends through the barrel member. The bore is sized and shaped so as to receive a medicated product therein and includes an opening formed in the dispensing end of the barrel member. The opening is sized and shaped so as to permit a medicated product received in the bore to be dispensed therethrough. The applicator is also provided with a plunger member movably extending through the bore of the barrel member for dispending a medicated product from the bore through the opening. The barrel member includes at least one substantially flexible section located between the dispending end and the proximal end such that the barrel member is bendable about the flexible section.

Abstract: An applicator for delivering pharmaceutical products or the like to a bodily cavity includes a barrel member having a distal end which is equipped with an opening. The applicator also includes a plurality of petals extending outwardly from the distal end in a generally axial direction. The petals cooperate with the opening so as to form a receptacle for releasably receiving a pharmaceutical product in the distal end of the barrel member. Each of the petals has a truncated flexible tip sized and shaped so as to engage a substantially central portion of the pharmaceutical product such that a large section of the pharmaceutical product extends outwardly beyond the petals so as to facilitate the release of the pharmaceutical product from the receptacle. The device also includes a plunger member for releasing the pharmaceutical product from the receptacle. In accordance with the present invention, the device can be packaged in a package together with the pharmaceutical product received in the receptacle.

Abstract: This invention relates to a novel method of manufacturing a lyophilized suppository composition wherein said suppository is made in situ in an applicator cartridge.