Patents by Inventor Paul Szymanski

Paul Szymanski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20130259806
    Abstract: The invention relates generally to dimeric molecular complexes comprising two fusion proteins. Each fusion protein comprises a biological effector moiety, a polypeptide spacer sequence, and an IgE CH4 dimerization domain. The dimeric molecular complexes may be conjugated, at a defined site, to other molecules including drug moieties, cytotoxic agents, labels (such as detectable labels), or biocompatible polymers.
    Type: Application
    Filed: December 7, 2011
    Publication date: October 3, 2013
    Inventors: David Light, Paul Szymanski, Marian Seto, Aline Cornelius
  • Publication number: 20110020925
    Abstract: The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.
    Type: Application
    Filed: April 11, 2008
    Publication date: January 27, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Maxine Bauzon, Peter Droescher, Richard N. Harkins, Terry Hermiston, Peter Kretschmer, Konstantin Levitsky, Paul Szymanski
  • Publication number: 20080076729
    Abstract: The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.
    Type: Application
    Filed: April 4, 2007
    Publication date: March 27, 2008
    Inventors: Maxine Bauzon, Richard Harkins, Terry Hermiston, Peter Kretschmer, Paul Szymanski
  • Publication number: 20070179113
    Abstract: The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.
    Type: Application
    Filed: April 4, 2007
    Publication date: August 2, 2007
    Inventors: Maxine Bauzon, Richard Harkins, Terry Hermiston, Peter Kretschmer, Harald Petry, Paul Szymanski
  • Publication number: 20060292609
    Abstract: The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.
    Type: Application
    Filed: May 18, 2006
    Publication date: December 28, 2006
    Applicant: Schering Aktiengesellschaft
    Inventors: Maxine Bauzon, Richard Harkins, Terry Hermiston, Peter Kretschmer, Paul Szymanski
  • Publication number: 20060281703
    Abstract: The present invention provides an improved, expression system for the regulated expression of an encoded protein or nucleic acid therapeutic molecule in the cells of a subject, for use in the treatment of disease. In particular, the present invention provides an improved, regulated gene expression system, and pharmaceutical compositions and uses thereof for treatment of disease.
    Type: Application
    Filed: May 18, 2006
    Publication date: December 14, 2006
    Applicant: Schering Aktiengesellschaft
    Inventors: Maxine Bauzon, Richard Harkins, Terry Hermiston, Peter Kretschmer, Paul Szymanski
  • Patent number: 5475741
    Abstract: This system is for use by a visitor to a facility that has multiple occupants, public-subscriber or other phone service, and an individual phone outlet at each occupant's part of the facility. A microphone and speaker are provided so that a visitor seeking access can speak with an occupant. A communication circuit carries signals between (1) the mike and speaker and (2) the phone service--to enable the conversation through an individual phone outlet. Manual controls, preferably including a standard phone keypad, are positioned for use by the visitor. An electronic memory holds directory information, particularly including occupant names and corresponding dial-up codes. An LCD, behind a protective window, shows the visitor the directory data. Names and other directory data can be fed into the memory remotely, preferably through either: ordinary phone connections using standard DTMF signals--with automated confirmation of input data by a voice-synthesis chip--or a modem.
    Type: Grant
    Filed: June 6, 1994
    Date of Patent: December 12, 1995
    Assignee: Sentex Systems, Inc.
    Inventors: William R. Davis, Dennis W. Mowers, Richard P. Greenthal, Paul Szymanski, Ronald A. Wray, Richard A. Davidson
  • Patent number: 5252955
    Abstract: A liquid-crystal display, preferably twenty-five lines of eighty characters each, is mounted in a case. The temperature of the display medium is maintained within operating limits for the display--notwithstanding ambient temperature and humidity variations over generally normal ranges for at least the temperate zones, and even if the display unit is placed to receive direct sunlight. The unit works outdoors as well as in buildings that lack temperature control. This is accomplished preferably by circulating air from outside the case through a space between the display face and an unperforated protective polycarbonate window. Intake and exhaust plena are long and narrow enough to deter manual access to the display and thus van dalism; however, the plena are straight and sufficiently free of obstructions that the fan can be a very small, low-power, quiet unit. A temperature sensor controls the fan, and also the contrast-adjusting voltage of the display --based on data in a digital-memory "look up" table.
    Type: Grant
    Filed: May 24, 1991
    Date of Patent: October 12, 1993
    Inventors: William R. Davis, Dennis W. Mowers, Richard P. Greenthal, Paul Szymanski, Ronald A. Wray, Richard A. Davidson
  • Patent number: 5027111
    Abstract: A liquid-crystal display, preferably twenty-five lines of eighty characters each, is mounted in a case. The temperature of the display medium is maintained within operating limits for the display--notwithstanding ambient temperature and humidity variations over generally normal ranges for at least the temperate zones, and even if the display unit is placed to receive direct sunlight. The unit works outdoors as well as in buildings that lack temperature control. This is accomplished preferably by circulating air from outside the case through a space between the display face and an unperforated protective polycarbonate window. Intake and exhaust plena are long and narrow enough to deter access to the display and thus vandalism; however, the plena are straight and sufficiently free of obstructions that the fan can be a very small, low-power, quiet unit. A temperature sensor controls the fan, and also the contrast-adjusting voltage of the display--based on data in a digital-memory "look up" table.
    Type: Grant
    Filed: July 7, 1988
    Date of Patent: June 25, 1991
    Assignee: Sentex Systems, Incorporated
    Inventors: William R. Davis, Dennis W. Mowers, Richard P. Greenthal, Paul Szymanski, Ronald A. Wray, Richard A. Davidson