Patents by Inventor Paul T. Matsudaira

Paul T. Matsudaira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6991713
    Abstract: A technique processes a sample of biomolecular analyte. The technique uses an apparatus having a support assembly that receives and supports a test module, a load assembly that loads the sample of biomolecular analyte onto the test module, an electrophoresis assembly that applies a current to the test module such that components within the sample separate by electrophoresis, and a controller that controls operations of the load assembly and the electrophoresis assembly. The load assembly and the electrophoresis assembly are coupled to the support assembly. The controller controls the operation of the load assembly in an automated manner. Preferably, the test module includes a dielectric plate member having an upper planar surface and a lower planar surface that is spaced apart from and coplanar with the upper planar surface. The dielectric plate member has at least one set of channels that includes an injection channel and a separation channel.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: January 31, 2006
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Aram S. Adourian, Daniel J. Ehrlich, Lance B. Koutny, Paul T. Matsudaira, Dieter R. Schmalzing
  • Publication number: 20010020588
    Abstract: A technique processes a sample of biomolecular analyte. The technique uses an apparatus having a support assembly that receives and supports a test module, a load assembly that loads the sample of biomolecular analyte onto the test module, an electrophoresis assembly that applies a current to the test module such that components within the sample separate by electrophoresis, and a controller that controls operations of the load assembly and the electrophoresis assembly. The load assembly and the electrophoresis assembly are coupled to the support assembly. The controller controls the operation of the load assembly in an automated manner. Preferably, the test module includes a dielectric plate member having an upper planar surface and a lower planar surface that is spaced apart from and coplanar with the upper planar surface. The dielectric plate member has at least one set of channels that includes an injection channel and a separation channel.
    Type: Application
    Filed: January 23, 2001
    Publication date: September 13, 2001
    Applicant: Whitehead Institute for Biomedical Research
    Inventors: Aram S. Adourian, Daniel J. Ehrlich, Lance B. Koutny, Paul T. Matsudaira, Dieter R. Schmalzing
  • Patent number: 6207031
    Abstract: A technique processes a sample of biomolecular analyte. The technique uses an apparatus having a support assembly that receives and supports a test module, a load assembly that loads the sample of biomolecular analyte onto the test module, an electrophoresis assembly that applies a current to the test module such that components within the sample separate by electrophoresis, and a controller that controls operations of the load assembly and the electrophoresis assembly. The load assembly and the electrophoresis assembly are coupled to the support assembly. The controller controls the operation of the load assembly in an automated manner. Preferably, the test module includes a dielectric plate member having an upper planar surface and a lower planar surface that is spaced apart from and coplanar with the upper planar surface. The dielectric plate member has at least one set of channels that includes an injection channel and a separation channel.
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: March 27, 2001
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Aram S. Adourian, Daniel J. Ehrlich, Lance B. Koutny, Paul T. Matsudaira, Dieter R. Schmalzing
  • Patent number: 5102518
    Abstract: An electroelutor provides electroelution and concentration of small amounts of proteins from sample gels. The electroelutor elutes desired molecules from gels in a sample holder directly onto a membrane of a centrifuge concentrator or a sequencing membrane. After electroelution, the eluted molecules can be concentrated or processed in a sequencing device with minimized sample handling and minimized disturbance abouFUNDINGWork described herein relating to the present invention has been funded under contract no. DK35 306 awarded by the National Institutes of Health.
    Type: Grant
    Filed: September 27, 1990
    Date of Patent: April 7, 1992
    Assignee: Whitehead Institute for Biomedical Research
    Inventors: Don S. Doering, Paul T. Matsudaira