Patents by Inventor Paul Thomas MACKLIN

Paul Thomas MACKLIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240069026
    Abstract: A method assessing tissue morphology using machine learning includes a step of training a machine learnable device to predict the status of a diagnostic feature in stained tissue samples. The machine learnable device is trained with a characterized set of digital images of stained tissue samples. Each digital image of the characterized set has a known status for the diagnostic feature and an extracted feature map provides values for a extracted feature over an associated 2-dimensional grid of spatial locations. A step of inputting the set of extracted feature maps is inputted into the machine learnable device to form associations therein between the set of extracted feature maps to and the known status for the diagnostic feature to form a trained machine learnable device. The status for the diagnostic feature of a stained tissue sample of unknown status for the diagnostic feature is predicted from the trained machine learnable device.
    Type: Application
    Filed: November 7, 2023
    Publication date: February 29, 2024
    Applicant: University of Southern California
    Inventors: David B. AGUS, Paul Thomas MACKLIN, Rishi Raghav RAWAT, Daniel Lee RUDERMAN
  • Patent number: 11835524
    Abstract: A method assessing tissue morphology using machine learning includes a step of training a machine learnable device to predict the status of a diagnostic feature in stained tissue samples. The machine learnable device is trained with a characterized set of digital images of stained tissue samples. Each digital image of the characterized set has a known status for the diagnostic feature and an extracted feature map provides values for a extracted feature over an associated 2-dimensional grid of spatial locations. A step of inputting the set of extracted feature maps is inputted into the machine learnable device to form associations therein between the set of extracted feature maps to and the known status for the diagnostic feature to form a trained machine learnable device. The status for the diagnostic feature of a stained tissue sample of unknown status for the diagnostic feature is predicted from the trained machine learnable device.
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: December 5, 2023
    Assignee: University of Southern California
    Inventors: David B. Agus, Paul Thomas Macklin, Rishi Raghav Rawat, Daniel Lee Ruderman
  • Publication number: 20200388028
    Abstract: A method assessing tissue morphology using machine learning includes a step of training a machine learnable device to predict the status of a diagnostic feature in stained tissue samples. The machine learnable device is trained with a characterized set of digital images of stained tissue samples. Each digital image of the characterized set has a known status for the diagnostic feature and an extracted feature map provides values for a extracted feature over an associated 2-dimensional grid of spatial locations. A step of inputting the set of extracted feature maps is inputted into the machine learnable device to form associations therein between the set of extracted feature maps to and the known status for the diagnostic feature to form a trained machine learnable device. The status for the diagnostic feature of a stained tissue sample of unknown status for the diagnostic feature is predicted from the trained machine learnable device.
    Type: Application
    Filed: March 6, 2018
    Publication date: December 10, 2020
    Applicant: UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: David B. AGUS, Paul Thomas MACKLIN, Rishi Raghav RAWAT, Daniel Lee RUDERMAN