Abstract: A search engine system generally includes a user interface in a computing environment configured to receive at least a first fragment from a user and a content display module configured to automatically generate an anticipated search result in the computing environment based on at least the first fragment. The content display module is configured to automatically display search results that include an arrangement of a plurality of visual content elements based on the anticipated search result. The content display module is configured to direct the user to content at one of a network and a local destination associated with one of the visual content elements selectable by the user with the user interface.

Abstract: We describe a user exercise-tolerance measuring pulse oximeter system, for determining the exercise tolerance or capacity of a user undergoing exercise, the system comprising: a wireless fingerband comprising an optical sensor to provide an oxygen saturation signal, a chargeable power supply, and a wireless transmitter/receiver; a motion detector to provide a user motion signal; and a signal processor coupled to said wireless fingerband to data from said optical sensor, and coupled to said motion detector; wherein said signal processor is configured to: process a combination of said oxygen saturation signal and said user motion signal to determine exercise tolerance data, wherein said exercise tolerance data is dependent upon said oxygen saturation signal and a level of exertion of said user determined from said user motion signal; and to time or count a period or quantity of user motion or movements, during said exercise, identified by said motion detector, to determine said level of exertion; to measure a d

Abstract: A search engine system generally includes a user interface in a computing environment configured to receive at least a first fragment from a user and a content display module configured to automatically generate an anticipated search result in the computing environment based on at least the first fragment. The content display module is configured to automatically display search results that include an arrangement of a plurality of visual content elements based on the anticipated search result. The content display module is configured to direct the user to content at one of a network and a local destination associated with one of the visual content elements selectable by the user with the user interface.

Abstract: We describe a user exercise-tolerance measuring pulse oximeter system, for determining the exercise tolerance or capacity of a user undergoing exercise, the system comprising: a wireless fingerband comprising an optical sensor to provide an oxygen saturation signal, a chargeable power supply, and a wireless transmitter/receiver; a motion detector to provide a user motion signal; and a signal processor coupled to said wireless fingerband to data from said optical sensor, and coupled to said motion detector; wherein said signal processor is configured to: process a combination of said oxygen saturation signal and said user motion signal to determine exercise tolerance data, wherein said exercise tolerance data is dependent upon said oxygen saturation signal and a level of exertion of said user determined from said user motion signal; and to time or count a period or quantity of user motion or movements, during said exercise, identified by said motion detector, to determine said level of exertion; to measure a d

Abstract: An assay device in which to carry out a fluid-phase chemical assay, comprising means for supporting a test substrate, a sample chamber for receiving a fluid sample and at least one fluid control device for controlling the movement of fluid into and/or out of the sample chamber, wherein the fluid control device comprises a fluid outlet chamber in fluid communication with the sample chamber, and a displaceable flexible diaphragm the displacement of which alters the volume of the outlet chamber so as to allow and/or restrict fluid flow between the outlet and sample chambers. The invention also provides assay apparatus incorporating such a device, an assay station for use as part of such apparatus, a fluid control unit for use as part of the assay device and a method of conducting an assay which may involve the use of such apparatus and devices.

Abstract: An assay device in which to carry out a fluid-phase chemical assay, comprising means for supporting a test substrate, a sample chamber for receiving a fluid sample and at least one fluid control device for controlling the movement of fluid into and/or out of the sample chamber, wherein the fluid control device comprises a fluid outlet chamber in fluid communication with the sample chamber, and a displaceable flexible diaphragm the displacement of which alters the volume of the outlet chamber so as to allow and/or restrict fluid flow between the outlet and sample chambers. The invention also provides assay apparatus incorporating such a device, an assay station for use as part of such apparatus, a fluid control unit for use as part of the assay device and a method of conducting an assay which may involve the use of such apparatus and devices.

Abstract: A system for automated excision of one or more samples from a sample media, including by using a device for electronically capturing one or more traits of samples in the media, using a microprocessor linked to the device to analyze the captured traits by comparison to reference databases, identifying samples of interest at location coordinates in the sample media, and automatically excising and processing the samples through the use of a novel robotic excision tool.

Abstract: A system for automated excision of one or more samples from a sample media, including by using a device for electronically capturing one or more traits of samples in the media, using a microprocessor linked to the device to analyze the captured traits by comparison to reference databases, identifying samples of interest at location coordinates in the sample media, and automatically excising and processing the samples through the use of a novel robotic excision tool.

Abstract: Electrophoretic separation device comprising first and second separation zones for containing first and second separation media, and barrier means, preferably automatically operable, by which fluid communication between the two zones may be reversibly prevented, the barrier means comprising a sealing element which is deformable between two positions to allow or prevent the fluid communication. The sealing element may comprise a flexible sheet carrying the first separation medium. Also provided are apparatus comprising such a separation device, and methods of electrophoretic separation, in one of which a first dimension separation is carried out in a chamber in the absence of any other separation medium, followed by introduction into the same chamber of a second separation medium, adjacent or in contact with the first, the analytes being allowed to migrate from the fist to the second separation medium prior to conducting the second dimension separation.

Abstract: An assay device in which to carry out a fluid-phase chemical assay, comprising means for supporting a test substrate, a sample chamber for receiving a fluid sample and at least one fluid control device for controlling the movement of fluid into and/or out of the sample chamber, wherein the fluid control device comprises a fluid outlet chamber in fluid communication with the sample chamber, and a displaceable flexible diaphragm the displacement of which alters the volume of the outlet chamber so as to allow and/or restrict fluid flow between the outlet and sample chambers. The invention also provides assay apparatus incorporating such a device, an assay station for use as part of such apparatus, a fluid control unit for use as part of the assay device and a method of conducting an assay which may involve the use of such apparatus and devices.

Abstract: An apparatus and method for chemical processing of multiple mixtures is disclosed. The apparatus provides selective purging of a liquid-phase of the mixtures. The apparatus can be used for processing many different types of mixtures under a wide variety of processing conditions, including but not limited to protein digestions, and is particularly well suited for processes requiring solid-liquid contacting. The apparatus includes an array of vessels or wells for containing the mixtures. The wells have openings that generally define a surface. A perforated plate and a film are disposed above the openings of the wells. The film is sandwiched between the perforated plate and the surface defined by the openings of the vessels, covering and sealing the vessels. A probe is used to perforate the film and to pressurize the vessels, which drives liquid out of the wells via through-holes formed in their bottoms.

Abstract: Placed near the transition point between power sources of different voltages or frequencies, is a wayside signal producing device which activates an on-board circuit for disconnecting the on-coming vehicle from the power source. When the vehicle has crossed the transition point, another signal producing device causes the vehicle to be connected to the other power source so as to resume power application. When the vehicle is proceeding in the opposite direction the sequence is reversed. In this way a multicar train can have the power source reliably switched in a car-by-car sequence without any appreciable loss in train speed.