Abstract: Method for detecting a urinary tract infection (UTI) in a subject comprising determining levels of one or more biomarkers selected from MMP8, HNE, Cystatin C, MMP9, HSA, IL-8, interleukin-6 (IL-6), interleukin-1 beta (IL-1b), fibrinogen, RBP4, active MMP9 and MMP2, NGAL, Desmosine, MPO and CRP in a urine sample obtained from the subject. The determined levels may then be compared with a threshold level, wherein increased levels of at least one of the biomarkers in the urine sample relative to the threshold level is indicative of the presence of a urinary tract infection. Methods for monitoring a UTI and monitoring treatment of a UTI are also provided as are companion systems or test kits.

Abstract: Methods, systems, and computer readable media for testing a system under test (SUT). An example system includes a fabric emulation device configured for emulating a data center switching fabric using emulated switch queues and for emulating one or more congestion control mechanisms for network traffic on the data center switching fabric from the SUT. The system includes a test execution manager configured for: executing a test case causing the fabric emulation device to invoke at least a first congestion control mechanism; logging one or more metrics characterizing the first congestion control mechanism in response to invoking the first congestion control mechanism, wherein logging the one or more metrics comprises logging at least one performance metric from at least one emulated switch queue of the fabric emulation device; and outputting a test report based on logging the one or more metrics.

Abstract: A breath actuated metered dose inhaler may comprise a canister fire system configured to fire a medicament containing canister in response to patient inhalation. The canister fire system may comprise a pneumatic force holding unit and having a rest configuration in which a metering valve of the canister is in a refill configuration; a prepared configuration in which a canister actuation force is retained by the pneumatic force holding unit and the canister fire system is actuatable by patient inhalation induced airflow; and a fire configuration in which the metering valve is in a dose delivery position. When in the prepared configuration, the force retained by the pneumatic force holding unit may be reduced by less than about 6% over a period of 5 minutes, preferably less than about 3% over a period of 5 minutes.

Abstract: Techniques are provided for implementing a unified object format. The unified object format is used to format data in a performance tier (e.g., infrequently accessed data, snapshot data, etc.) into objects that are stored into an object store for low cost, scalable, long term storage compared to storage of the performance tier. With the unified object format, compression of the data may be retained when the data is stored as the objects into the object store. Additional compression may also be provided for the data in the objects. The unified object format includes slot header metadata used to track the location of the data within the object notwithstanding the data being compressed and/or stored at non-fixed boundaries. The slot header metadata may be cached at the performance tier for improved read performance and may be repaired by a repair subsystem (a slot header repair subsystem).

Abstract: A hand held spray dispenser in which air and liquid are pressurised towards a mixing chamber by energy generated by a manual activation element that is rotated with a unidirectional twist to energise one or more energy storage bodies, energy from which is released to generate sufficient air pressure and air flow and sufficient liquid flow for a spray to be formed from the air-liquid mixture.

Abstract: Techniques are provided for remote object store error handling. A storage system may store data within one or more tiers of storage, such as a local storage tier (e.g., solid state storage and disks maintained by the storage system), a remote object store (e.g., storage provided by a third party storage provider), and/or other storage tiers. Because the remote object store may not provide the same data consistency and guarantees that the storage system provides for clients such as through the local storage tier, additional validation is provided by the storage system for the remote object store. For example, when data is put into an object of the remote object store, a verification get operation is performed to read and validate information within a header of the object. Other verifications and checks are performed such as using a locally stored metafile to detect corrupt or lost metadata and/or objects.

Abstract: One example method occurs in a test environment comprising network emulation platforms (NEPs), wherein the NEPs implement an emulated switching fabric comprising emulated switches, wherein the NEPs are connected via at least one physical cable. The method includes determining, using a network test system controller, at least one routing path group for communications between the emulated switches, wherein each of the at least one routing path group includes or uses virtual links utilizing one or more lanes of the at least one physical cable; configuring, using the network test system controller, physical ports of the NEPs to assign traffic during a test session to one of the virtual links based on a routing path group identifier associated with the traffic; and initiating, using the network test system controller, the test session involving the test environment.

Abstract: Articles of footwear and methods of making articles of footwear including one or more continuous threads wound around anchor points. The winding of the one or more continuous threads forms a thread pattern that imparts desired characteristics to components of the article of footwear. Thread lines of the thread pattern may be bonded together. In some embodiments, thread lines may be bonded with a bonding layer.

Abstract: A stent scaffold combined with amniotic tissue provides for a biocompatible stent that has improved biocompatibility and hemocompatibility. The amnion tissue can be variously modified or unmodified form of amnion tissue such as non-cryo amnion tissue, solubilized amnion tissue, amnion tissue fabric, chemically modified amnion tissue, amnion tissue treated with radiation, amnion tissue treated with heat, or a combination thereof. Materials such as polymer, placental tissue, pericardium tissue, small intestine submucosa can be used in combination with the amnion tissue. The amnion tissue can be attached to the inside, the outside, both inside and outside, or complete encapsulation of the stent scaffold. In some embodiments, at least part of the covering or lining comprises a plurality of layers of amnion tissue. The method of making the biocompatible stent and its delivery and deployment are also discussed.

Abstract: The disclosure provides antibody constructs that can reversibly bind to biological or chemical target analytes. Upon target analyte binding, the antibody construct can change its conformational state to produce a detectable readout. An antibody construct can be a single-antibody construct or a dual-antibody construct.

Abstract: A radar system includes two circuit boards, a first carries an array of antenna elements and the second carries power circuitry to power the circuitry of the first board. To provide adequate cooling whilst minimising the size of the system the two circuit boards are mounted in a sandwich arrangement on opposite sides of a heat sink. Data and power connections between the two boards are provided by a plurality of electrical cables that extend through apertures in the heat sink.

Abstract: A messaging apparatus for wearable items. The messaging apparatus may comprise a light source, at least one sensor to detect are event, and a controller to control the flashing of the light source in response to the detection of the event. The controlling of the flashing of the light source may generate at least one visible element that is visible to a viewer. Further, the light source may not be adapted in the form of the at least one visible element, but rather, the controlled flashing of the light source may be in the form of the at least one visible element.

Abstract: A method of associating a first party and a second party is provided, the method comprising receiving a first electronic message comprising information indicative of the first party; generating a first electronic token in response to receiving the information indicative of the first party; sending the first electronic token to the first party; receiving one or more second electronic messages from the second party, the one or more second electronic messages comprising the first electronic token and information indicative of the second party; generating a second electronic token in response to receiving the first electronic token and the information indicative of the second party from the second party; associating the information indicative of the first party, the second party and the second electronic token, the first party being identified on the basis of the first electronic token, and sending the second electronic token to the first party.

Abstract: Described herein are compositions and methods for treating inflammation, and inflammation-related conditions, using fumarate or fumarate analogs or inhibitors of fumarate hydratase (FH).

Abstract: A process allows the extraction of heavy hydrocarbon compounds from solid substrates in an economical and efficient fashion. Materials containing heavy hydrocarbons (i.e. oil sands or roofing shingles) are broken up into an auger and then mixed with light hydrocarbons. Subsequently, the resulting slurry is shaken to separate fluids from solids, and the fluids are subjected to one or more filtering processes to remove waste sediment. These filtering processes may include a series of one or more of centrifuges and nozzle purifier machines. Filtered fluids are distilled to separate heavy hydrocarbons from light hydrocarbons. Simultaneously, the solids are heated to remove the remaining light hydrocarbons as vapors. Light hydrocarbons are cooled in a condenser and coalesced in a holding tank, wherefrom they may be recirculated into the process and used repeatedly. The now-isolated heavy hydrocarbons resulting from the distillation process may be removed as a purified product.

Abstract: A messaging apparatus for wearable items. The messaging apparatus may comprise a light source, at least one sensor to detect are event, and a controller to control the flashing of the light source in response to the detection of the event. The controlling of the flashing of the light source may generate at least one visible element that is visible to a viewer. Further, the light source may not be adapted in the form of the at least one visible element, but rather, the controlled flashing of the light source may be in the form of the at least one visible element.

Abstract: A messaging apparatus for wearable items. The messaging apparatus may comprise a light source, at least one sensor to detect an event, and a controller to control the flashing of the light source in response to the detection of the event. The controlling of the flashing of the light source may generate at least one visible element that is visible to a viewer. Further, the light source may not be adapted in the form of the at least one visible element, but rather, the controlled flashing of the light source may be in the form of the at least one visible element.

Abstract: A radar system includes two circuit boards, a first carries an array of antenna elements and the second carries power circuitry to power the circuitry of the first board. To provide adequate cooling whilst minimising the size of the system the two circuit boards are mounted in a sandwich arrangement on opposite sides of a heat sink. Data and power connections between the two boards are provided by a plurality of electrical cables that extend through apertures in the heat sink.