Patents by Inventor Paul van Eikeren
Paul van Eikeren has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20080162530Abstract: A computer-readable extensible markup language data structure comprising structural elements for defining a data-analysis parts container in a data-analysis template comprising a word processor document is disclosed. The computer-readable data structure is comprised of at least one properties element for receiving properties associated with the data-analysis parts container and at least one data-analysis parts element for receiving data-analysis parts, wherein the properties and data-analysis parts elements define the data-analysis container. The computer-readable extensible markup language data structure allows the user/programmer to perform data analysis within the familiar environment of a word processor application using data-analysis templates. The extensible markup language data structure also allows the user/programmer to generate a programmable object model for accessing XLM-defined resources of the data-analysis parts container.Type: ApplicationFiled: January 3, 2007Publication date: July 3, 2008Applicant: Blue Reference, Inc.Inventors: Paul van Eikeren, Joshua S. van Eikeren
-
Publication number: 20080159633Abstract: An interactive data-analysis part pane is provided for receiving and displaying a data-analysis part in a word processor application. The interactive data-analysis part pane includes a content region for receiving and displaying the data-analysis part in at least one predefined area of the word processor document in a data-analysis template. The content region shares data with the data-analysis part in the data-analysis part container and the data-analysis template comprises a word processor document comprising a data-analysis parts container.Type: ApplicationFiled: January 3, 2007Publication date: July 3, 2008Applicant: Blue Reference, Inc.Inventors: Paul van Eikeren, Joshua S. van Eikeren
-
Publication number: 20080163043Abstract: A computer-implemented method for generating data-analysis results in a word processing program is disclosed. The method may entail the following: providing a data-analysis template, wherein the data-analysis template comprises a word processor document comprising a data-analysis parts container; including at least one data-analysis part in the data-analysis parts container; communicating the data-analysis parts container to a data-analysis processor for generating a data-analysis results collection using the data-analysis parts container; and generating a data-analysis results document.Type: ApplicationFiled: January 3, 2007Publication date: July 3, 2008Applicant: Blue Reference, Inc.Inventors: Paul van Eikeren, Joshua S. van Eikeren
-
Patent number: 6618852Abstract: An object oriented framework provides a set of objects that perform chemical-process-development decision-support functioning and that permit a framework user to add extensions for specific processing features, thereby producing an application program that supports decision-making during chemical development activities.Type: GrantFiled: September 13, 1999Date of Patent: September 9, 2003Assignee: Intellichem, Inc.Inventors: Paul van Eikeren, Joshua S. van Eikeren
-
Patent number: 5827538Abstract: An osmotic device that, following the imbibement of water vapor, provides for the controlled release of a beneficial agent to an aqueous environment. The device comprises a hydrophilic formulation including a beneficial agent, and if needed, an osmagent, surrounded by a wall. The wall is formed at least in part of a semipermeable hydrophobic membrane having an average pore size between about 0.1 .mu.m and 30 .mu.m. The pores are substantially filled with a gas phase. The hydrophobic membrane is permeable to water in the vapor phase and the hydrophobic membrane is impermeable to an aqueous medium at a pressure less than about 100 Pa. The beneficial agent is released, for example, by osmotic pumping or osmotic bursting upon imbibement of sufficient water vapor into the device core.Type: GrantFiled: January 17, 1996Date of Patent: October 27, 1998Assignee: Pfizer Inc.Inventors: Edward L. Cussler, Scott M. Herbig, Kelly L. Smith, Paul van Eikeren
-
Patent number: 5677469Abstract: A process for the full or partial resolution of a mixture of enantiomers of a genus of chiral carboxylic acids is disclosed. The process uses a pure enantiomer of 1-aminoindan-2-ol as the resolving agent and achieves separation of the diastereomeric salts by fractional crystallization followed by liberation of the chiral acid from the salt by treatment with mineral acid. Diastereomeric salts and solyates of those salts are disclosed. The production of ketoprofen, flurbiprofen and other chiral medicaments and precursors thereto is disclosed.Type: GrantFiled: May 18, 1995Date of Patent: October 14, 1997Assignee: Sepracor, Inc.Inventors: Paul van Eikeren, Francis X. McConville, Jorge L. Lopez
-
Patent number: 5603953Abstract: Supported liquid membrane delivery devices that release a beneficial agent to an aqueous environment following exposure to an environmental trigger. A microporous hydrophobic support membrane at least partially surrounds a beneficial agent- containing hydrophilic formulation. A hydrophobic liquid is held within the microporous support membrane by capillarity and the hydrophobic liquid is substantially permeable to the aqueous environment and the beneficial agent-containing hydrophilic formulation. The entrained hydrophobic liquid becomes substantially permeable to the aqueous environment upon exposure to an environmental trigger such as an enzyme, and the beneficial agent is subsequently released.Type: GrantFiled: May 23, 1995Date of Patent: February 18, 1997Assignee: Pfizer Inc.Inventors: Scott M. Herbig, Kelly L. Smith, Paul Van Eikeren, James B. West
-
Patent number: 5350681Abstract: The present invention discloses a method for the enzymatic synthesis of a peptide. A protected peptide having a C-terminal carboxylate group or a protected, N-acyl amino acid having an alpha carboxylate group is reacted with a protected peptide having an N-terminal ammonium group or a protected amino acid having an alpha ammonium group in the presence of a condensation enzyme under conditions in which the carboxylate group and the ammonium group condense to form a protected, uncharged, peptide product. This peptide product is transported across a water-immiscible hydrophobic phase into an aqueous product phase and prevented from back diffusing across the water-immiscible hydrophobic phase. The peptide product can be converted, chemically or enzymatically, to a charged species that cannot back diffuse across the water-immiscible phase into the aqueous reaction phase.Type: GrantFiled: August 12, 1992Date of Patent: September 27, 1994Assignee: The Coca-Cola CompanyInventors: Guillermo A. Iacobucci, Daniel J. Brose, Roderick J. Ray, Paul van Eikeren
-
Patent number: 5263409Abstract: There are disclosed two types of apparatus using membrane extractions of citrus juice bittering agents, both using extraction fluids. In one type, a membrane contactor facilitates contact between bittering agents present in a citrus juice feed and a hydrophobic bittering agents extraction fluid; a second membrane contactor may be used to extract bittering agents from the hydrophobic extraction fluid by use of a basic stripping fluid on the permeate side. In a second type, an immobilized liquid membrane containing hydrophobic extraction fluid supported within the pores of a microporous hydrophobic polymeric membrane is used to facilitate transport of bittering agents across the membrane.Type: GrantFiled: April 24, 1992Date of Patent: November 23, 1993Assignee: Bend Research, Inc.Inventors: Paul van Eikeren, Daniel J. Brose
-
Patent number: 5241087Abstract: A method of enantiomerically enriching chiral cyanohydrins is disclosed that involves selective cleavage of the unwanted enantiomer into its cleavage products HCN and the corresponding aldehyde or ketone by use of an enantioselective dehydrocyanation catalyst, coupled with simultaneous removal of at least one of the dehydrocyanation products.Type: GrantFiled: March 9, 1992Date of Patent: August 31, 1993Assignee: Bend Research, Inc.Inventor: Paul van Eikeren
-
Patent number: 5091080Abstract: Semipermeable membrane-enclosed solid core adsorbent devices for the selective removal of volatile chemical species from an aqueous environment are disclosed.Type: GrantFiled: November 30, 1990Date of Patent: February 25, 1992Assignee: Bend Research, Inc.Inventors: Paul van Eikeren, Daniel J. Brose, Scott M. Herbig
-
Patent number: 5071561Abstract: A supported-fluid membrane process for the removal of inhibitory ammonia formed during the culturing of mammalian cells is disclosed.Type: GrantFiled: February 24, 1989Date of Patent: December 10, 1991Assignee: Bend Research, Inc.Inventors: Paul van Eikeren, John M. Radovich
-
Patent number: 5041227Abstract: An improvement to processes for the selective extractation of organic solutes from organic solvents by water-based extractants is disclosed, the improvement comprising coupling various membrane separation processes with the organic extraction process, the membrane separation process being utilized to continuously recycle the water-based extractant and at the same time selectively remove or concentrate organic solute from the water-based extractant.Type: GrantFiled: October 9, 1990Date of Patent: August 20, 1991Assignee: Bend Research, Inc.Inventors: Paul van Eikeren, Daniel J. Brose, Roderick J. Ray
-
Patent number: RE35230Abstract: A method of enantiomerically enriching chiral cyanohydrins is disclosed that involves selective cleavage of the unwanted enantiomer into its cleavage products HCN and the corresponding aldehyde or ketone by use of an enantioselective dehydrocyanation catalyst, coupled with simultaneous removal of at least one of the dehydrocyanation products.Type: GrantFiled: February 7, 1994Date of Patent: May 7, 1996Assignee: Bend Research, Inc.Inventor: Paul van Eikeren