Abstract: Devices, systems and methods for removing heat from subcutaneously disposed lipid-rich cells are disclosed. In selected embodiments, suction and/or heat removal sources are coupled to an applicator. The applicator includes a flexible portion and a rigid portion. The rigid portion includes a thermally conductive plate and a frame coupling the thermally conductive plate and the flexible portion. An interior cavity of the applicator is in fluid communication with the suction source, and the frame maintains contiguous engagement between the heat removal source and the thermally conductive plate.

Abstract: An inflatable cuff may be adapted to seal a vessel of a patient, such as a trachea when associated with a medical device, such as an endotracheal tube. In one embodiment, an inflatable cuff made from multiple layers is provided where one or more layers are chosen to improve sealing of the tube in the vessel. In exemplary embodiments, the individual layers may improve sealing by swelling in the presence of moisture, being wettable by the tissues of the trachea, or both. In one implementation, the inflatable cuff may be made of any combination of layers that perform either or both of these functions.

Abstract: A composition or cryoprotectant for use with a system for improved cooling of subcutaneous lipid-rich tissue of a subject having skin is provided. The cryoprotectant is a non-freezing liquid, gel, or paste for allowing pre-cooling of a treatment device below about 0° C. while preventing the formation of ice thereon. The cryoprotectant may also prevent freezing of the treatment device to the skin and protect tissue of a subject from freezing damage due to, e.g., ice formation. The cryoprotectant can also include an authentication or anti-counterfeiting agent to authenticate an origin of the cryoprotectant, a lubricating agent to increase lubriciousness of the cryoprotectant, and a thixotropic or pseudoplastic agent in an amount effective substantially to render the gel dimensionally stable unless agitated.

Abstract: An inflatable balloon cuff associated with a tracheal tube may be adapted to filter microbial secretions and reduce their passage into the lungs. A cuff as provided may include a cross-linked polymeric structure that may serve to exclude certain secretions on the basis of size. The polymeric structure may be incorporated onto all or part of the surface of the inflatable balloon cuff.

Abstract: A medical device includes a conduit for a fluid. The conduit has a wall formed of a hydrophobic polymer with a hydrophilic polymer layer extruded over it, and an antimicrobial substantially dispersed within the hydrophilic polymer. The antimicrobial compound may be a predetermined amount of phosphorus-based glass having a predetermined quantity of a metal such as silver substantially dispersed therein. The medical device may be an endotracheal tube made by providing a hydrophobic polymer, a hydrophilic polymer and an antimicrobial compound, forming the hydrophobic polymer, the hydrophilic polymer and the antimicrobial compound into a conduit, and forming a cuff on an end of the conduit.

Abstract: A fluid warming device for warming medical fluids, such as intravenously administered blood or saline solutions, is provided. The fluid warming device includes a conduit at least partially formed from a material with positive temperature coefficient properties. A supply of blood or other fluids may pass through the device and be heated to temperatures appropriate for administration to a patient.

Abstract: An inflatable balloon cuff associated with a tracheal tube may be adapted to filter microbial secretions and reduce their passage into the lungs. A cuff as provided may include a cross-linked polymeric structure that may serve to exclude certain secretions on the basis of size. The polymeric structure may be incorporated onto all or part of the surface of the inflatable balloon cuff.

Abstract: An inflatable cuff may be adapted to seal a vessel of a patient, such as a trachea when associated with a medical device, such as an endotracheal tube. In one embodiment, an inflatable cuff made from multiple layers is provided where one or more layers are chosen to improve sealing of the tube in the vessel. In exemplary embodiments, the individual layers may improve sealing by swelling in the presence of moisture, being wettable by the tissues of the trachea, or both. In one implementation, the inflatable cuff may be made of any combination of layers that perform either or both of these functions.

Abstract: An inflatable balloon cuff may be adapted to include a gas barrier material in order to seal a patient's trachea when associated with an endotracheal tube. The gas barrier material may preserve a cuff's mechanical pressure seal during lengthy intubation times or during surgical procedures. The gas barrier on the inflatable cuff may be a general gas barrier, or may be specific to certain gases.

Abstract: There is disclosed an endotracheal tube to which an adhesion-resistant material, adhesion-resistant material is applied. Several techniques are disclosed for applying the adhesion-resistant material, adhesion-resistant material, including surface treatments, co-extrusion, and compounding. The adhesion-resistant material, adhesion-resistant material helps prevent the adhesion of microbes to the surface of the endotracheal tube. In this manner the cross-sectional area through which the patient may breathe is increased, effectively decreasing the work of breathing for the patient.

Abstract: A fluid warming device for warming medical fluids, such as intravenously administered blood or saline solutions, is provided. The fluid warming device includes a conduit at least partially formed from a material with positive temperature coefficient properties. A supply of blood or other fluids may pass through the device and be heated to temperatures appropriate for administration to a patient.

Abstract: A medical device includes a conduit for a fluid. The conduit has a wall formed of a hydrophobic polymer with a hydrophilic polymer layer extruded over it, and an antimicrobial substantially dispersed within the hydrophilic polymer. The antimicrobial compound may be a predetermined amount of phosphorus-based glass having a predetermined quantity of a metal such as silver substantially dispersed therein. The medical device may be an endotracheal tube made by providing a hydrophobic polymer, a hydrophilic polymer and an antimicrobial compound, forming the hydrophobic polymer, the hydrophilic polymer and the antimicrobial compound into a conduit, and forming a cuff on an end of the conduit.

Abstract: Conventional foamable cavity sealing articles are susceptible to sagging when expanded in a vertical orientation with the foaming material facing downwards, because of gravitational drag on the molten material during expansion. The problem is particularly pronounced in foaming materials formulated to have high expansion ratios and low melt viscosities. A solution to the problem is presented in the form of a cavity sealing article having a planar holder and a foamable sealer, the foamable sealer circumscribing the edge of the support member. This construction creates a gripping effect which prevents sagging of the sealing member during expansion.