Patents by Inventor Paul W. O'Toole

Paul W. O'Toole has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for Stratifying IBS Patients
    Publication number: 20210327580
    Abstract: A computer-implemented method for stratifying a patient with irritable bowel syndrome (IBS). The method comprises detecting the presence, absence, or abundance of multiple bacteria in a biological sample obtained from the patient to generate a patient microbiome profile; and operating a trained classifier on the patient microbiome profile to output a signal stratifying the patient with irritable bowel syndrome (IBS) into a first group or a second group. Stratification of the patient into the first group is indicative that the patient has a not significantly altered microbiome in comparison to the average microbiome not indicative of IBS. Stratification of the patient into the second group is indicative that the patient has an altered microbiome in comparison to the average microbiome not indicative of IBS.
    Type: Application
    Filed: December 4, 2020
    Publication date: October 21, 2021
    Inventors: Fergus SHANAHAN, Paul W. O'TOOLE, Ian B. JEFFERY
  • Lactobacillus rhamnosus polynucleotides, polypeptides and methods for using them
    Patent number: 7052896
    Abstract: Novel polynucleotides isolated from Lactobacillus rhamnosus, as well as probes and primers, genetic constructs comprising the polynucleotides, biological materials, including plants, microorganisms and multicellular organisms incorporating the polynucleotides, polypeptides expressed by the polynucleotides, and methods for using the polynucleotides and polypeptides are disclosed.
    Type: Grant
    Filed: October 2, 2001
    Date of Patent: May 30, 2006
    Inventors: Matthew Glenn, IIkka J. Havukkala, Leonard N. Bloksberg, Mark W. Lubbers, James Dekker, Anna C. Christensson, Ross Holland, Paul W. O'Toole, Julian R. Reid, Timothy Coolbear
  • Polynucleotides, materials incorporating them, and methods for using them
    Patent number: 6544772
    Abstract: Novel polynucleotides isolated from Lactobacillus rhamnosus, as well as probes and primers, genetic constructs comprising the polynucleotides, biological materials, including plants, microorganisms and multicellular organisms incorporating the polynucleotides, polypeptides expressed by the polynucleotides, and methods for using the polynucleotides and polypeptides are disclosed.
    Type: Grant
    Filed: August 8, 2000
    Date of Patent: April 8, 2003
    Assignees: Genesis Research & Development Corp. Ltd, Via Lachia Bioscience (NZ) Ltd.
    Inventors: Matthew Glenn, Ilkka J. Havukkala, Leonard N. Bloksberg, Mark W. Lubbers, James Dekker, Anna C. Christensson, Ross Holland, Paul W. O'Toole, Julian R. Reid, Timothy Coolbear
  • Lactobacillus rhamnosus polynucleotides, polypeptides and methods for using them
    Publication number: 20020159976
    Abstract: Novel polynucleotides isolated from Lactobacillus rhamnosus, as well as probes and primers, genetic constructs comprising the polynucleotides, biological materials, including plants, microorganisms and multicellular organisms incorporating the polynucleotides, polypeptides expressed by the polynucleotides, and methods for using the polynucleotides and polypeptides are disclosed.
    Type: Application
    Filed: October 2, 2001
    Publication date: October 31, 2002
    Inventors: Matthew Glenn, Ilkka J. Havukkala, Leonard N. Bloksberg, Mark W. Lubbers, James Dekker, Anna C. Christensson, Ross Holland, Paul W. O'Toole, Julian R. Reid, Timothy Coolbear