Patents by Inventor Paul W. Zinke

Paul W. Zinke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Patent number: 6933392
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: May 28, 2003
    Date of Patent: August 23, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Paul W. Zinke
  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Patent number: 6884816
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Grant
    Filed: August 30, 2002
    Date of Patent: April 26, 2005
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Paul W. Zinke
  • 5-Hydroxyl indole derivatives for treating glaucoma
    Patent number: 6806285
    Abstract: Novel 3-(2-aminopropyl)-H-indol-5-ols useful for lowering and controlling IOP and treating glaucoma are disclosed.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: October 19, 2004
    Assignee: Alcon, Inc.
    Inventors: Jesse A. May, Paul W. Zinke
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Publication number: 20040198817
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Application
    Filed: April 20, 2004
    Publication date: October 7, 2004
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke, George E. Barnes, Michael L. Chandler, Thomas R. Dean, Jesse A. May, Louis Desantis
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6723748
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues in combination with carbonic anhydrase inhibitors for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor.
    Type: Grant
    Filed: February 5, 2002
    Date of Patent: April 20, 2004
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke
  • 15-fluoro prostaglandins as ocular hypotensives
    Patent number: 6680339
    Abstract: 15-fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: January 20, 2004
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • 15-fluoro prostaglandins as ocular hypotensives
    Patent number: 6649653
    Abstract: 15-Fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: November 18, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Publication number: 20030181503
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: May 28, 2003
    Publication date: September 25, 2003
    Inventors: Jesse A. May, Paul W. Zinke
  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Publication number: 20030181504
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: May 28, 2003
    Publication date: September 25, 2003
    Inventors: Jesse A. May, Paul W. Zinke
  • Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
    Publication number: 20030083346
    Abstract: Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles are disclosed. Also disclosed are methods for the lowering and controlling of normal or elevated intraocular pressure as well as a method for the treatment of glaucoma using compositions containing one or more of the compounds of the present invention.
    Type: Application
    Filed: August 30, 2002
    Publication date: May 1, 2003
    Inventors: Jesse A. May, Paul W. Zinke
  • 15-fluoro prostaglandins as acular hypotensives
    Publication number: 20020151587
    Abstract: 15-fluoro substituted analogs of PGF2&agr; and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Application
    Filed: March 18, 2002
    Publication date: October 17, 2002
    Inventors: Peter G. Klimko, Mark R. Hellberg, Paul W. Zinke
  • 11-halo prostaglandins for the treatment of glaucoma or ocular hypertension
    Patent number: 6353000
    Abstract: A method of treating glaucoma or ocular hypertension in a patient, which comprises administering to the patient a pharmaceutically effective amount of a compound of formula I:
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 5, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Verney L. Sallee, Mark R. Hellberg, Peter G. Klimko, Paul W. Zinke
  • Method of prostaglandin synthesis
    Patent number: 6344581
    Abstract: Methods of synthesizing 9-Halo-13,14-dihydroprostaglandins useful in the treatment of glaucoma and ocular hypertension are disclosed. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 31, 1997
    Date of Patent: February 5, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Raymond E. Conrow, Paul W. Zinke, Peter G. Klimko, Robert D. Selliah
  • Use of cis-&Dgr;4 analogs of prostaglandins as ocular hypotensives
    Patent number: 6235779
    Abstract: Cis-&Dgr;4 analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: May 22, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, Paul W. Zinke
  • Substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 6197812
    Abstract: Substituted tetrahydrofuran analogs of prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: November 15, 1999
    Date of Patent: March 6, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert D. Selliah, Mark R. Hellberg, Peter G. Klimko, Verney L. Sallee, Paul W. Zinke
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 6184250
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues and combinations thereof with other medicaments for the treatment of glaucoma and ocular hypertension and ophthalmic compositions therefor. Also disclosed are methods of treating optic nerve disorders using the cloprostenol and fluprostenol analogues.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: February 6, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke, Tom R. Dean, George E. Barnes, Michael L. Chandler
  • 13-Thia prostaglandins for use in glaucoma therapy
    Patent number: 6172109
    Abstract: 13-thia prostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising said prostaglandins.
    Type: Grant
    Filed: June 3, 1998
    Date of Patent: January 9, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Paul W. Zinke, Mark R. Hellberg
  • Conformationally rigid aryl prostaglandins for use in glaucoma therapy
    Patent number: 6169111
    Abstract: Conformationally rigid aryl prostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic pharmaceutical compositions comprising said prostaglandins.
    Type: Grant
    Filed: May 12, 1999
    Date of Patent: January 2, 2001
    Assignee: Alcon Laboratories, Inc.
    Inventors: Paul W. Zinke, John E. Bishop, Thomas R. Dean, Mark R. Hellberg
  • substituted tetrahydrofuran analogs of prostaglandins as ocular hypotensives
    Patent number: 6025392
    Abstract: Substituted tetrahydrofuran analogs of F-series prostaglandins and methods of their use in treating glaucoma and ocular hypertension are disclosed.
    Type: Grant
    Filed: July 2, 1998
    Date of Patent: February 15, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert D. Selliah, Mark R. Hellberg, Peter G. Klimko, Verney L. Sallee, Paul W. Zinke
  • Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
    Patent number: 5889052
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.
    Type: Grant
    Filed: August 21, 1997
    Date of Patent: March 30, 1999
    Assignee: Alcon Laboraties, Inc.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke