Abstract: A system and method for distribution of a clock signal of a new timing reference which may employ an existing NTSC distribution network present in a conventional NTSC studio. NTSC-compliant horizontal, vertical, or other composite synchronization signals are generated from an HDTV primary reference clock, and are synchronized and locked to the HDTV primary reference, for distribution over the existing NTSC distribution network. HDTV studio components receive the horizontal, vertical, or other composite synchronization signals and generate a local HDTV clock signal using a phase-locked loop frequency synthesizer. The signal generated by the phase-locked loop frequency synthesizer is synchronized and locked to the HDTV primary reference.

Abstract: A timing synchronization method and apparatus for processing a compressed information stream comprising a plurality of information segments representative of a sequence of information frames. Information segments representative of information frames are deleted in response to an indicium of buffer overutilization.

Abstract: The invention provides for the production of several humanized murine antibodies specific for the Lewis b antigen, which is recognized by the murine antibody 58-1066. The antigen is expressed on cell lines from colon, lung, bladder, breast, renal, pancreatic and ovarian cancers. The expression of the antigen is greatly increased in cancer tissues as compared to its expression in the corresponding normal tissue. The invention also provides for numerous polynucleotide encoding humanized Lewis b antigen specific antibodies, expression vectors for producing humanized Lewis b antigen specific antibodies, and host cells for the recombinant production of the humanized antibodies. The invention also provides methods for detecting cancerous cells (in vitro and in vivo) using humanized Lewis b antigen specific antibodies. Additionally, the invention provides methods of treating cancer using Lewis b antigen specific antibodies.

Abstract: A method and apparatus for storing data values received within respective cycle periods of a clock signal are disclosed. Data values are alternately stored in first and second data hold registers and then output by each data hold register for a time greater than a cycle period of the clock signal. Address values at which the incoming data values are to be written are alternately stored in first and second address hold registers. Data stored in the first data hold register is written to a latch-based memory element in a first memory bank indicated by an address value stored in the first address hold register. Data stored in the second data hold register is written to a latch-based memory element in a second memory bank indicated by an address value stored in the second address hold register.

Abstract: The invention provides for the production of several humanized murine antibodies specific for the antigen LK26, which is recognized by the murine antibody LK26. This antigen is expressed on all choriocarcinoma, teratocarcinoma and renal cancer cell lines whereas it is not expressed on cell lines of leukaemias, lymphomas, neuroectodermally-derived and epithelial tumour cell lines (excepting a small subset of epithelial cell lines). Furthermore, whereas renal cancer cell lines express the LK26 antigen, normal renal epithelial cells do not. Similarly, with the exception of the trophoblast, all normal adult and fetal tissues tested are negative for the LK26 phenotype. The invention also provides for numerous polynucleotide encoding humanized LK26 specific antibodies, expression vectors for producing humanized LK26 specific antibodies, and host cells for the recombinant production of the humanized antibodies.

Abstract: A studio to transmitter link (STL) that comprises a relatively low error rate communication channel implements error correction techniques at the studio side which are designed to reduce errors in the combined low error rate STL channel and a relatively high error rate communication channel used by the transmitter.

Abstract: A transmitted high definition television signal is represented by a packetized datastream configured as a sequence of data fields with a non-uniform data rate due to different types of different duration non-data overhead information. Each data field is prefaced by a Field Sync overhead segment followed by 312 packetized data segments each with associated overhead information. At a transmitter, a transport processor forms data packets with associated headers and exhibits uninterrupted operation at a constant uniform data rate, while supplying a packetized datastream to a network which constructs sequential data fields by inserting the non-data overhead information into the datastream. The transport processor is advantageously operated at a constant uniform data rate without having to modify the original data field structure to accommodate the needs of the data field construction network.

Abstract: A transport stream encoder comprises a plurality of component signal sources. One of the component signals sources is a source of an opportunistic data component signal carrying a block of data having a predetermined size to be transferred within a predetermined period of time. A packet generator is coupled to the plurality of component signal sources, and produces a composite packet stream, partitioned into successive groups containing a plurality of packet slots. A memory stores a plurality of priority lists respectively associated with the plurality of packet slots. Each priority list contains a plurality of entries, and each entry contains data representing a respective one of the plurality of component signal sources. A scheduler is responsive to the entries in the plurality of priority lists and conditions the packet generator to generate a packet for each one of the packet slots.

Abstract: A system of the present invention addresses the difficulty of aligning a reference sync byte at the beginning of a data packet during situations where the system experiences severe problems such as arbitrary resets/restarts or transmission disturbances. Specifically, the sync byte at the beginning of the data packet is automatically aligned with the beginning of a data acquisition interval when data is requested, even when there are arbitrary system resets/restarts. The alignment of the first data packet following a system reset is facilitated by the use of a Start Of Packet flag concurrent with the reference byte, together with a controlled logic network.

Abstract: A transmission processor (16) receives an input packetized datastream (FIGS. 6-9; FIGS. 15-18 signal A) containing packets of data bytes including MPEG coded video information. The transmission processor outputs a symbol datastream (FIGS. 15-18 signal F) representing a sequence of data fields (FIG. 1) comprising groups of data segments (X) with an associated field sync segment. The transmission processor inserts overhead information. e.g., FEC error coding information, into each data segment, and inserts the longer duration field sync overhead segment between groups of data field segments. The frequency of the transmission processor input byte clock (SC/2, FIG. 6; FIG. 15) an integer sub-multiple of an output symbol clock (SC) frequency. The input datastream exhibits constant uniform inter-packet data gaps and a constant uniform data rate, thereby facilitating the seamless insertion of the field sync overhead segment into the datastream without interrupting the datastream.

Abstract: The invention provides for the production of several humanized murine antibodies specific for the antigen FB5, which is recognized by the murine antibody FB5. The FB5 antigen is expressed on the luminal surface of vascular endothelial cells of a wide range of malignant tumours. The invention also provides for numerous polynucleotide encoding humanized FB5 specific antibodies, expression vectors for producing humanized FB5 specific antibodies, and host cells for the recombinant production of the humanized antibodies. The invention also provides methods for detecting cancerous cells (in vitro and in vivo) using humanized FB5 specific antibodies. Additionally, the invention provides methods of treating cancer using FB5 specific antibodies.

Abstract: The invention provides for the production of several humanized murine antibodies specific for the Lewis b antigen, which is recognized by the murine antibody 58-1066. The antigen is expressed on cell lines from colon, lung, bladder, breast, renal, pancreatic and ovarian cancers. The expression of the antigen is greatly increased in cancer tissues as compared to its expression in the corresponding normal tissue. The invention also provides for numerous polynucleotide encoding humanized Lewis b antigen specific antibodies, expression vectors for producing humanized Lewis b antigen specific antibodies, and host cells for the recombinant production of the humanized antibodies. The invention also provides methods for detecting cancerous cells (in vitro and in vivo) using humanized Lewis b antigen specific antibodies. Additionally, the invention provides methods of treating cancer using Lewis b antigen specific antibodies.

Abstract: A method is disclosed for optimizing the operation of a packet transport system generating a packet stream carrying a plurality of component signals, and includes the following steps. First the packet stream is partitioned into successive groups, each group containing a predetermined number of packet slots. A plurality of lists are maintained, one associated with each packet slot in a group. A packet stream is generated by placing data representing a component signal selected in response to entries in the list associated with that packet slot into the packet slot. The contents of the plurality of lists are updated based on a predetermined parameter.

Abstract: The invention provides for the production of several humanized murine antibodies specific for the antigen LK26, which is recognized by the murine antibody LK26. This antigen is expressed on all choriocarcinoma, teratocarcinoma and renal cancer cell lines whereas it is not expressed on cell lines of leukaemias, lymphomas, neuroectodermally-derived and epithelial tumour cell lines (excepting a small subset of epithelial cell lines). Furthermore, whereas renal cancer cell lines express the LK26 antigen, normal renal epithelial cells do not. Similarly, with the exception of the trophoblast, all normal adult and fetal tissues tested are negative for the LK26 phenotype. The invention also provides for numerous polynucleotide encoding humanized LK26 specific antibodies, expression vectors for producing humanized LK26 specific antibodies, and host cells for the recombinant production of the humanized antibodies.

Abstract: A liquid composition for application as a coating to screens of video display terminals (VDT's). The composition comprises a mixture of pure silica as a flattening agent, a surface active copolymer to minimize the build-up of static electricity on the surface of the screen, hydroxyethyl cellulose polymer as a thickener and glycerol as a carrier. The ingredients are present in relative concentrations so as to be effective for their intended purpose in the final mixture. The composition according to the present invention when applied as a coating to a VDT screen results in dispersion or defraction of light in a very effective manner, while at that same time reducing static electricity on the screen and cleaning the screen.

Abstract: A method of measuring the load in a member subjected to longitudinal stress, a load measuring device and a fastener tightening device using the method of measuring, a load indicating member and a load indicating fastener for use in conjunction with the method of measuring, a method of making the load indicating fastener, and a method of tightening the load indicating fastener. A preselected end of a pin is secured to a shank of a load indicating member, such as a load indicating fastener, in a manner such that the pin is unaffected by the elastic deformation of the shank in response to longitudinal stress. Coplanar first and second flat surfaces are formed, respectively, adjacent to the longitudinal ends of the pin and the shank furthest from the preselected end of the pin such as to provide reference surfaces for the measurement of the elongation of the shank in response to longitudinal stress.

Abstract: A method of measuring the load in a member subjected to longitudinal stress, a load measuring device and a fastener tightening device using the method of measuring, a load indicating member and a load indicating fastener for use in conjunction with the method of measuring, a method of making the load indicating fastener, and a method of tightening the load indicating fastener. A preselected end of a pin is secured to a shank of a load indicating member, such as a load indicating fastener, in a manner such that the pin is unaffected by the elastic deformation of the shank in response to longitudinal stress. Coplanar first and second flat surfaces are formed, respectively, adjacent to the longitudinal ends of the pin and the shank furthest from the preselected end of the pin such as to provide reference surfaces for the measurement of the elongation of the shank in response to longitudinal stress.