Patents by Inventor Paul Wayne Brown

Paul Wayne Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
    Publication number: 20230405137
    Abstract: The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.
    Type: Application
    Filed: November 4, 2021
    Publication date: December 21, 2023
    Inventors: Paul Wayne Brown, Kaushik Dutta, Jason Arnold Lotvin, Kelly Jeffrey Sackett
  • Novel 4-diphenylmethyl piperidine derivatives
    Publication number: 20040167169
    Abstract: This invention relates to novel substituted piperidine derivatives. More particularly, this invention relates to substituted phenyl 4-substituted-piperidinoalkanol derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Application
    Filed: March 1, 2004
    Publication date: August 26, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Kah Hiing Ling, Paul Wayne Brown, Robert M. Strom, Richard A. Wolf
  • Method for the isolation of sulfuric acid mono-[3({1-[2-(4-fluorophenyly)-ethyl]-piperidin-4-yl}-2-methoxy-phenyl}ester
    Publication number: 20040152900
    Abstract: The present invention is directed to the method of isolation of sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester, a metabolite of the 5HT2A antagonist (+)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.
    Type: Application
    Filed: January 20, 2004
    Publication date: August 5, 2004
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Ronald Charles Bernotas, Paul Wayne Brown, Gary Thomas Emmons, Chi-Hsin Richard King
  • Sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-YL}-hydroxy-methyl)-2-methoxy-phenyl]ester
    Patent number: 6716986
    Abstract: The present invention is directed to sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester, a metabolite of the 5HT2A antagonist (+)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and a processes for its preparation and its use in the treatment for a number of disease states.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: April 6, 2004
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Ronald Charles Bernotas, Paul Wayne Brown, Gary Thomas Emmons, Chi-Hsin Richard King
  • Novel 4-diphenylethyl piperidine derivatives
    Publication number: 20030065186
    Abstract: This invention relates to novel substituted piperidine derivatives. More particularly, this invention relates to substituted phenyl 4-substituted-piperidinoalkanol derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Application
    Filed: October 3, 2002
    Publication date: April 3, 2003
    Inventors: Kah Hiing Ling, Paul Wayne Brown, Robert M. Strom, Richard A. Wolf
  • Sulfuric acid mono-[3({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester
    Patent number: 6465490
    Abstract: The present invention is directed to sulfuric acid mono-[3-({1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-hydroxy-methyl)-2-methoxy-phenyl]ester a metabolite of the 5HT2A antagonist (+)-&agr;-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol and a processes for its preparation and its use in the treatment for a number of disease states.
    Type: Grant
    Filed: July 13, 2000
    Date of Patent: October 15, 2002
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Ronald Charles Bernotas, Paul Wayne Brown, Gary Thomas Emmons, Chi-Hsin Richard King
  • Novel 4-diphenylmethyl piperdine derivatives
    Publication number: 20020016467
    Abstract: This invention relates to novel substituted piperidine derivatives. More particularly, this invention relates to substituted phenyl 4-substituted-piperidinoalkanol derivatives which are useful as antihistamines, antiallergy agents and bronchodilators.
    Type: Application
    Filed: October 2, 2001
    Publication date: February 7, 2002
    Inventors: Kah Hiing Ling, Paul Wayne Brown, Robert M. Strom, Richard A. Wolf