Patents by Inventor Paul Weissensee

Paul Weissensee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Identifying molecules modulating protein-protein interactions using protease activated reporters
    Patent number: 9023610
    Abstract: Assay methods and systems use enzymatic cleavage resulting from protein-protein interaction to modulate (activate or inactivate) a reporter.
    Type: Grant
    Filed: October 2, 2013
    Date of Patent: May 5, 2015
    Assignee: Sanofi
    Inventors: Paul Steven Wright, Paul Weissensee, Haifeng Eishingdrelo, Jidong Cai
  • IDENTIFYING MOLECULES MODULATING PROTEIN-PROTEIN INTERACTIONS USING PROTEASE ACTIVATED REPORTERS
    Publication number: 20140162289
    Abstract: Assay methods and systems use enzymatic cleavage resulting from protein-protein interaction to modulate (activate or inactivate) a reporter.
    Type: Application
    Filed: October 2, 2013
    Publication date: June 12, 2014
    Applicant: SANOFI
    Inventors: Paul Steven WRIGHT, Paul Weissensee, Haifeng Eishingdrelo, Jidong Cai
  • Methods and assays for identifying compounds that modulate protein-protein interactions
    Patent number: 8574865
    Abstract: Methods and assays for identifying a compound that modulates a protein-protein interaction between a first and a second protein. The methods and assays require a protease that is attached to the second protein and a split and rearranged reporter activating protein that is attached to the first protein, wherein the reporter activating protein comprises a cleavage site for the protease that is interposed between two portions of the reporter activating protein and wherein the two portions of the reporter activating protein are in a rearranged order.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: November 5, 2013
    Assignee: Sanofi
    Inventors: Paul Steven Wright, Paul Weissensee, Haifeng Eishingdrelo, Jidong Cai
  • IDENTIFYING MOLECULES MODULATING PROTEIN-PROTEIN INTERACTIONS USING PROTEASE ACTIVATED REPORTERS
    Publication number: 20100311096
    Abstract: Assay methods and systems use enzymatic cleavage resulting from protein-protein interaction to modulate (activate or inactivate) a reporter.
    Type: Application
    Filed: August 28, 2008
    Publication date: December 9, 2010
    Applicant: SANOFI-AVENTIS
    Inventors: Paul Steven Wright, Paul Weissensee, Haifeng Eishingdrealo, Jidong Cai
  • Gave10 agonists for treating inflammation
    Publication number: 20060111331
    Abstract: Disclosed is a method for inhibiting TNF?, IL-6, and activating GAVE10, treating, for example, inflammation thereby, the method comprising the step of administering to a subject an effective amount of a compound of the following formula: or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof, wherein B1 and B2 are each independently —OH, (C1-C6)alkyl, or —H; X is Z-K; Z is —CO or —CH2; K is —N(R1)n, —NR1N(R2)n, —NR1R5R2R4, —N(R1)pR2NR3R4, or —N(R1)pR5R2R4 R1, R2, and R3 are each independently (C1-C6)alkyl or absent; n is from 0 to 3; p is from 0 to 2; R4 is absent or is R5 is absent or is
    Type: Application
    Filed: November 23, 2004
    Publication date: May 25, 2006
    Applicant: Aventis Pharmaceuticals Inc.
    Inventors: Haifeng Eishingdrelo, Kin Yu, Jidong Cai, Paul Weissensee, Jian Shen
  • Novel G protein-coupled purinergic receptor, GAVE17
    Publication number: 20030215878
    Abstract: Novel GAVE17 polypeptides, proteins and nucleic acid molecules are provided. In addition to isolated, full-length GAVE17 proteins, isolated GAVE17 fusion proteins, antigenic peptides and anti-GAVE17 antibodies are taught.
    Type: Application
    Filed: April 7, 2003
    Publication date: November 20, 2003
    Inventors: Haifeng Eishingdrelo, Theresa Kuntzweiler, Paul Weissensee, Jidong Cai, Johan Gassenhuber