Patents by Inventor Paul Wiedeman

Paul Wiedeman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV)
    Publication number: 20080119464
    Abstract: The present invention relates to compounds of formula (I), which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: January 30, 2008
    Publication date: May 22, 2008
    Inventors: Irini Akritopoulou-Zanze, Daria Darczak, Jurgen Dinges, Stevan Djuric, Ethan Hoff, Hana Kopecka, Jyoti Patel, Zhonghua Pei, Qi Shuai, Kathy Sarris, Hing Sham, Paul Wiedeman
  • PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV)
    Publication number: 20070265302
    Abstract: The present invention relates to compounds which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: July 25, 2007
    Publication date: November 15, 2007
    Inventors: David Madar, Stevan Djuric, Melissa Michmerhuizen, Hana Kopecka, Xiaofeng Li, Kenton Longenecker, Zhonghua Pei, Daisy Pireh, Hing Sham, Kent Stewart, Bruce Szezepankiewicz, Paul Wiedeman, Hong Yong
  • Pharmaceutical Compositions as Inhibitors of Dipeptidyl Peptidase-IV (DPP-IV)
    Publication number: 20070238753
    Abstract: The present invention relates to compounds that inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: June 1, 2007
    Publication date: October 11, 2007
    Inventors: David Madar, Stevan Djuric, Melissa Michmerhuizen, Hana Kopecka, Xiaofeng Li, Kenton Longenecker, Zhonghua Pei, Daisy Pireh, Hing Sham, Kent Stewart, Bruce Szczepankiewicz, Paul Wiedeman, Hong Yong
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20050215784
    Abstract: The present invention relates to compounds that inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, Syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: January 13, 2005
    Publication date: September 29, 2005
    Inventors: David Madar, Stevan Djuric, Melissa Michmerhuizen, Hana Kopecka, Xiaofeng Li, Kenton Longenecker, Zhonghua Pei, Daisy Pireh, Hing Sham, Kent Stewart, Bruce Szczepankiewicz, Paul Wiedeman, Hong Yong
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20050215603
    Abstract: The present invention relates to compounds of formula (I), which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: March 8, 2004
    Publication date: September 29, 2005
    Inventors: Irini Akritopoulou-Zanze, Daria Darczak, Jurgen Dinges, Stevan Djuric, Ethan Hoff, Hana Kopecka, Jyoti Patel, Zhonghua Pei, Qi Shuai, Kathy Sarris, Hing Sham, Paul Wiedeman
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20050209249
    Abstract: The present invention relates to compounds of formula (I), which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, obesity, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: March 8, 2005
    Publication date: September 22, 2005
    Inventors: Irini Akritopoulou-Zanze, Daria Darczak, Jurgen Dinges, Stevan Djuric, Ethan Hoff, Hana Kopecka, Jyoti Patel, Zhonghua Pei, Qi Shuai, Kathy Sarris, Hing Sham, Paul Wiedeman
  • Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV)
    Publication number: 20050131019
    Abstract: The present invention relates to compounds of formula (I), which inhibit dipeptidyl peptidase IV (DPP-IV) and are useful for the prevention or treatment of diabetes, especially type II diabetes, as well as hyperglycemia, syndrome X, hyperinsulinemia, ?-cell failure, obesity, satiety disorders, atherosclerosis, and various immunomodulatory diseases.
    Type: Application
    Filed: September 7, 2004
    Publication date: June 16, 2005
    Inventors: Zhonghua Pei, Xiaofeng Li, Kenton Longenecker, Hing Sham, Paul Wiedeman
  • Macrocyclic immunomodulators
    Patent number: 5708002
    Abstract: Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same.
    Type: Grant
    Filed: October 23, 1996
    Date of Patent: January 13, 1998
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, Megumi Kawai, Yat Sun Or, Paul Wiedeman, Rolf Wagner
  • Macrocyclic immunomodulators
    Patent number: 5457111
    Abstract: Immunomodulatory macrocyclic compounds having the formula ##STR1## and pharmaceutically acceptable salts, esters, amides and prodrugs thereof, wherein X is selected from one of the formulae ##STR2## as well as pharmaceutical compositions containing the same.
    Type: Grant
    Filed: November 9, 1993
    Date of Patent: October 10, 1995
    Assignee: Abbott Laboratories
    Inventors: Jay R. Luly, Megumi Kawai, Yat S. Or, Paul Wiedeman, Rolf Wagner
  • Hexa- and heptapeptide anaphylatoxin-receptor ligands
    Patent number: 5387671
    Abstract: Oligopeptide compounds or oligopeptide analogue compounds of the formula A-B-D-E-G-J-L-M-Q are ligands for the anaphylatoxin receptor and are useful in the treatment of inflammatory disease states.Also disclosed are anaphylatoxin receptor ligand compositions and a method for modulating anaphylatoxin activity.
    Type: Grant
    Filed: December 27, 1990
    Date of Patent: February 7, 1995
    Assignee: Abbott Laboratories
    Inventors: Megumi Kawai, Paul Wiedeman, Jay R. Luly, Yat S. Or