Patents by Inventor Paul Willem Henri Ida PARREN

Paul Willem Henri Ida PARREN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES THAT BIND PSMA AND GAMMA-DELTA T CELL RECEPTORS
    Publication number: 20240317888
    Abstract: The present invention relates to antibodies capable of binding human PSMA and capable of binding a human V?9V?2 T cell receptor. The invention further relates to pharmaceutical compositions comprising the antibodies of the invention and to uses of the antibodies of the invention for medical treatment.
    Type: Application
    Filed: May 6, 2024
    Publication date: September 26, 2024
    Inventors: Robertus Cornelis ROOVERS, Johannes Jelle VAN DER VLIET, Lisa Anna KING, Paul Willem Henri Ida PARREN, Victoria IGLESIAS GUIMARAIS, David LUTJE HULSIK, Peter Alexander Gerardus Maria MACHIELSEN
  • Bispecific antibodies for use in the treatment of hematological malignancies
    Patent number: 12077586
    Abstract: The present invention relates to novel methods for the treatment of hematological malignancies. In particular, the invention relates to the treatment of hematological malignancies using antibodies comprising a first binding moiety that is able to bind human CD1d and a second binding moiety that is able to bind the human V?9V?2-TCR.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: September 3, 2024
    Assignee: LAVA THERAPEUTICS N.V.
    Inventors: Iris De Weerdt, Arnon Philip Kater, Paul Willem Henri Ida Parren, Tanja Denise De Gruijl, Johannes Jelle Van Der Vliet, Roeland Lameris
  • ANTIBODIES THAT BIND CD123 AND GAMMA-DELTA T CELL RECEPTORS
    Publication number: 20240141071
    Abstract: The present invention relates to antibodies capable of binding human CD123 and capable of binding the V?2 chain of a human V?9V?2 T cell receptor. The invention further relates to pharmaceutical compositions comprising the antibodies of the invention and to uses of the antibodies of the invention for medical treatment.
    Type: Application
    Filed: February 28, 2022
    Publication date: May 2, 2024
    Inventors: Robertus Cornelis ROOVERS, Johannes Jelle VAN DER VLIET, David LUTJE HULSIK, Paul Willem Henri Ida PARREN, Jurjen Matthijs RUBEN, Charlotte Merette MOUSSET
  • ANTIBODIES THAT BIND GAMMA-DELTA T CELL RECEPTORS
    Publication number: 20230303694
    Abstract: The present invention relates to antibodies capable of binding a human V?9V?d2 T cell receptor. The invention further relates to pharmaceutical compositions comprising the antibodies of the invention and to uses of the antibodies of the invention for medical treatment.
    Type: Application
    Filed: June 9, 2023
    Publication date: September 28, 2023
    Inventors: Paul Willem Henri Ida PARREN, Robertus Cornelis ROOVERS, Johannes Jelle VAN DER VLIET, David LUTJE HULSIK, Peter Alexander Gerardus Maria MACHIELSEN, Michiel VAN WESTERHOVEN, Lisa Anna KING, Felix-Lennart FENNEMANN
  • ANTIBODIES THAT BIND PSMA AND GAMMA-DELTA T CELL RECEPTORS
    Publication number: 20230272110
    Abstract: Provided herein are antibodies capable of binding human PSMA and capable of binding a human V?9V?2 T cell receptor. In particular, provided herein are pharmaceutical compositions comprising the antibodies capable of binding human PSMA and capable of binding a human V?9V? T cell receptor and uses of the antibodies for medical treatment.
    Type: Application
    Filed: July 8, 2021
    Publication date: August 31, 2023
    Inventors: Robertus Cornelis Roovers, Johannes Jelle VAN DER VLIET, Lisa Anna KING, Paul Willem Henri Ida PARREN, Victoria IGLESIAS GUIMARAIS, David LUTJE HULSIK, Peter Alexander Gerardus Maria MACHIELSEN
  • TREATMENT OF CANCER COMPRISING ADMINISTRATION OF Vg9Vd2 T CELL RECEPTOR BINDING ANTIBODIES
    Publication number: 20230036284
    Abstract: The invention relates to methods for the treatment of cancer. In particular, the invention relates to methods for the treatment of cancer, comprising administration of a high dose of an antibody capable of binding a human V?9V?2 T cell receptor.
    Type: Application
    Filed: September 16, 2020
    Publication date: February 2, 2023
    Inventors: Robertus Cornelis Roovers, Gerard Joseph Maria Jean Horbach, Thilo Alexander Riedl, Johannes Jelle Van Der Vliet, Paul Willem Henri Ida Parren
  • DUAL ACTING CD1D IMMUNOGLOBULIN
    Publication number: 20220111043
    Abstract: The present invention relates to the field of immunology, more in particular to the field of binding moieties and/or immunoglobulins which bind to human CD1d, including antibodies and fragments thereof that modify CD1d-mediated biological functions such as enhanced activation and reduced activation of CD1d-restricted T cells, including the natural killer T-cells and gamma-delta T-cells, and modulation of the function of cells expressing CD1d. The invention also relates to bi-, tri- or multi-specific immunoglobulins that bind to CD1d and a gamma-delta TCR and/or a tumor target. The invention further relates to pharmaceutical preparations and use of such mono-, bi-, and tri- or multi-specific binding moieties and/or immunoglobulins in the treatment of diseases or disorders.
    Type: Application
    Filed: September 19, 2019
    Publication date: April 14, 2022
    Inventors: Johannes Jelle VAN DER VLIET, Roeland LAMERIS, Tanja Denise DE GRUIJL, Paul Willem Henri Ida PARREN
  • NOVEL BISPECIFIC ANTIBODIES FOR USE IN THE TREATMENT OF HEMATOLOGICAL MALIGNANCIES
    Publication number: 20210371525
    Abstract: The present invention relates to novel methods for the treatment of hematological malignancies. In particular, the invention relates to the treatment of hematological malignancies using antibodies comprising a first binding moiety that is able to bind human CD1d and a second binding moiety that is able to bind the human V?9V?2-TCR.
    Type: Application
    Filed: September 19, 2019
    Publication date: December 2, 2021
    Inventors: Iris DE WEERDT, Arnon Philip KATER, Paul Willem Henri Ida PARREN, Tanja Denise DE GRUIJL, Johannes Jelle VAN DER VLIET, Roeland LAMERIS