Patents by Inventor Paul William Groundwater

Paul William Groundwater has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme inhibitors
    Patent number: 9856230
    Abstract: The present subject matter relates generally to compounds having the formula (I): wherein each of X, Y, R1, R2, R3, R4, and n are as defined herein. Compounds of formula (I) may act as inhibitors of the thioredoxin reductase enzyme system. The subject matter also relates to use, formulation and preparation of the compounds. The compounds may be useful in the treatment of inflammatory and oxidative diseases and conditions. The compounds may also provide useful anti-proliferative and anti-apoptotic effects.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: January 2, 2018
    Assignee: UNIVERSITY OF SUNDERLAND
    Inventors: Adam Todd, Rosaleen Joy Anderson, David Antony Phillip Small, Paul William Groundwater, Matthew Richard Benton
  • Enzyme Inhibitors
    Publication number: 20150322035
    Abstract: The present subject matter relates generally to compounds having the formula (I): wherein each of X, Y, R1, R2, R3, R4, and n are as defined herein. Compounds of formula (I) may act as inhibitors of the thioredoxin reductase enzyme system. The subject matter also relates to use, formulation and preparation of the compounds. The compounds may be useful in the treatment of inflammatory and oxidative diseases and conditions. The compounds may also provide useful anti-proliferative and anti-apoptotic effects.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 12, 2015
    Inventors: Adam Todd, Rosaleen Joy Anderson, David Antony Philip Small, Paul William Groundwater, Matthew Richard Benton
  • Melatonin derivatives and their use as antioxidants
    Patent number: 8258173
    Abstract: The present subject matter relates generally to antioxidant compounds having the formula (I): wherein each of R1, R2, R3, and R4 are as defined below. These compounds are potentially useful as, for example, antioxidants.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: September 4, 2012
    Assignee: University of Sunderland
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, David Antony Philip Small, Yu Gong
  • Enzymatic substrates derived from phenoxazinone and their use as developers in detection of microorganisms with peptidase activity
    Patent number: 7932050
    Abstract: Enzymatic phenoxazinone substrates of formula (I): in reaction media containing the same are used for detecting, identifying and/or quantifying microorganisms expressing at least one peptidase activity.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: April 26, 2011
    Assignee: bioMerieux
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, Arthur James, Daniel Monget, Andrey Victorovich Zaytsev
  • MELATONIN DERIVATIVES AND THEIR USE AS ANTIOXIDANTS
    Publication number: 20100063125
    Abstract: The present subject matter relates generally to antioxidant compounds having the formula (I): wherein each of R1, R2, R3, and R4 are as defined below. These compounds are potentially useful as, for example, antioxidants.
    Type: Application
    Filed: November 19, 2007
    Publication date: March 11, 2010
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, David Antony Philip Small, Yu Gong
  • Novel enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity
    Publication number: 20100028926
    Abstract: Novel enzymatic substrates of the general formula below: reaction media containing the same, and their use for detecting, identifying, and/or quantifying microorganisms expressing at least one peptidase activity.
    Type: Application
    Filed: September 22, 2009
    Publication date: February 4, 2010
    Applicant: BIOMERIEUX
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, Arthur James, Daniel Monget, Andrey Victorovich Zaytsev
  • Enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity
    Patent number: 7626018
    Abstract: Novel enzymatic substrates of the general formula below: reaction media containing the same and their use for detecting and/or identifying and/or quantifying microorganisms expressing at least one peptidase activity.
    Type: Grant
    Filed: September 9, 2005
    Date of Patent: December 1, 2009
    Assignee: bioMérieux
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, Arthur James, Daniel Monget, Andrey Victorovich Zaytsev
  • Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity
    Publication number: 20080293094
    Abstract: The invention concerns novel enzymatic substrates of the general formula below: wherein: R1, R2, R3, R4, R5, R6, A and X are as defined in claim 1, reaction media containing same and their use for detecting and/or identifying and/or quantifying microorganisms expressing at least one peptidase activity.
    Type: Application
    Filed: September 9, 2005
    Publication date: November 27, 2008
    Applicant: Biomerieux
    Inventors: Arthur James, Daniel Monget, Andrey Victorovich Zaytsev, Rosaleen Joy Anderson, Paul William Groundwater