Abstract: Filaments that contain a filament-forming material and an additive, nonwoven webs, and methods for making such filaments are provided.

Abstract: A method for delivering one or more oral care active agents to a mammal's mouth using a nonwoven web of filaments and/or fibers containing one or more oral care active agents that are releasable from the filaments and/or fibers is provided.

Abstract: Embodiments are directed to structural fuses, structures including the same, and methods of using and forming the same. In an embodiment, a structural fuse is disclosed. The structural fuse includes a first attachment region defining one or more first bolt holes, a second attachment region defining one or more second bolt holes, and a yielding region between the first attachment region and the second attachment region. The yielding region defines one or more slots exhibiting an elongated shape.

Abstract: An example buckling restrained brace (“BRB”) includes a casing exhibiting a hollow cross-sectional shape defining an interior region. The BRB also includes a core and at least a portion of the core is disposed in the interior region of the casing. For example, the casing may exhibit a first length and the core may exhibit a second length that is greater than the first length such that a portion of the core extends from the casing. The core is separated from the casing by an minimum gap distance along at least a portion of the first length of the casing and a corresponding portion of the second length of the core.

Abstract: Embodiments are directed to structural fuses and connection systems including the same. An example structural fuse includes at least one plate. The structural fuse includes a plurality of cutouts formed in the plate. The cutouts are configured to cause at least one first yield region of the plate to yield when a first load is applied to the plate. Optionally, the plurality of cutouts are configured to cause at least one second yield region to yield when a second load is applied to the plate. At least a portion of the first yield region is distinct from at least a portion of the second yield region and the first load is different than the second load.

Abstract: Embodiments are directed to base connections, structures including base connections, kits for forming the base connections and/or structures, and method of repairing yielded base connections. In an embodiment, a base connection includes a base plate including a top surface and a bottom surface opposite the top surface. The top surface is configured to be adjacent to a terminal end of a column and the bottom surface adjacent to a foundation. The connection also includes one or more anchor rods attached to the base plate. The anchor rods are configured to secure the base plate to the foundation. The connection includes at least one structural fuse configured to be attached to the column and attached to the base plate. The fuse includes a plate with at least one cutout formed therein. The cutout is configured to form one or more yield regions that are configured to preferentially yield.

Abstract: Column-to-beam connection systems are disclosed herein, along with moment-resisting frames including the same and methods of repairing the same. An example column-to-beam connection system includes a shear component. The shear component includes abase plate that is connected to a column flange. The shear component also includes at least one vertical web extending from the base plate. The vertical web is connected to with a beam flange. The vertical web also defines one or more openings therein.

Abstract: An example buckling restrained brace (“BRB”) includes a casing exhibiting a hollow cross-sectional shape defining an interior region. The BRB also includes a core and at least a portion of the core is disposed in the interior region of the casing. For example, the casing may exhibit a first length and the core may exhibit a second length that is greater than the first length such that a portion of the core extends from the casing. The core is separated from the casing by an minimum gap distance along at least a portion of the first length of the casing and a corresponding portion of the second length of the core.

Abstract: Disclosed are peptide conjugates that are calcitonin gene-related peptide (CGRP) receptor antagonists comprising a CGRP peptide, wherein at least one amino acid of the peptide is covalently conjugated to a lipid-containing moiety. Also disclosed are pharmaceutical compositions and kits comprising such conjugates, methods of preparing such conjugates, and uses of such antagonists.

Abstract: Embodiments disclosed herein relate to a beam-to-column connection systems for a moment-resisting frame as well as moment-resisting frames that include such connection systems.

Abstract: Embodiments disclosed herein relate to a beam-to-column connection systems for a moment-resisting frame as well as moment-resisting frames that include such connection systems.

Abstract: Various embodiments disclosed herein relate to moment-resisting frames, kits for assembling such moment-resisting frames, and methods of repairing such moment-resisting frames. In an embodiment, a moment-resisting frame includes a beam connected to a column using a moment-resisting connection. The moment-resisting connection may include at least one exterior doubler plate (“EDP”) that is connected to the column and two or more connectors that are connected to both the beam and the EDP. In some embodiments, the moment-resisting frame may require less welding than conventional beam-to-column connections. Additionally or alternatively, such a moment-resisting frame may eliminate the need for components typically used in conventional beam-to-column connections (e.g., continuity plates).

Abstract: Various embodiments disclosed herein relate to moment-resisting frames, kits for assembling such moment-resisting frames, and methods of repairing such moment-resisting frames. In an embodiment, a moment-resisting frame includes a beam connected to a column using a moment-resisting connection. The moment-resisting connection may include at least one exterior doubler plate (“EDP”) that is connected to the column and two or more connectors that are connected to both the beam and the EDP. In some embodiments, the moment-resisting frame may require less welding than conventional beam-to-column connections. Additionally or alternatively, such a moment-resisting frame may eliminate the need for components typically used in conventional beam-to-column connections (e.g., continuity plates).

Abstract: Various embodiments disclosed herein relate to moment-resisting frames, kits for assembling such moment-resisting frames, and methods of repairing such moment-resisting frames. In an embodiment, a moment-resisting frame includes a beam connected to a column using a moment-resisting connection. The moment-resisting connection may include at least one exterior doubler plate (“EDP”) that is connected to the column and two or more connectors that are connected to both the beam and the EDP. In some embodiments, the moment-resisting frame may require less welding than conventional beam-to-column connections. Additionally or alternatively, such a moment-resisting frame may eliminate the need for components typically used in conventional beam-to-column connections (e.g., continuity plates).

Abstract: Embodiments disclosed herein relate to a beam-to-column connection systems for a moment-resisting frame as well as moment-resisting frames that include such connection systems.

Abstract: Embodiments disclosed herein relate to a beam-to-column connection systems for a moment-resisting frame as well as moment-resisting frames that include such connection systems.

Abstract: Embodiments of this invention include synthetic compounds (NRP analogues) of peptides termed neural regeneration peptides (NRPs). NRP analogues are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizing ?-turns, acetylation of terminal glycine residues or by cyclization. NRP analogues can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.

Abstract: Various embodiments disclosed herein relate to moment-resisting frames, kits for assembling such moment-resisting frames, and methods of repairing such moment-resisting frames. In an embodiment, a moment-resisting frame includes a beam connected to a column using a moment-resisting connection. The moment-resisting connection may include at least one exterior doubler plate (“EDP”) that is connected to the column and two or more connectors that are connected to both the beam and the EDP. In some embodiments, the moment-resisting frame may require less welding than conventional beam-to-column connections. Additionally or alternatively, such a moment-resisting frame may eliminate the need for components typically used in conventional beam-to-column connections (e.g., continuity plates).

Abstract: Embodiments of this invention include synthetic compounds (NRP analogs) of peptides termed neural regeneration peptides (NRPs). NRP analogs are made by substituting amino acids in the native peptide sequence, modifying amino acids chemically, by replacing amino acids with synthetic moieties, by stabilizing ?-turns, acetylation of terminal glycine residues or by cyclization. NRP analogs can be used to treat a variety of conditions involving degeneration of neural cells, and includes treating disorders of the nervous system, including peripheral neuropathy, multiple sclerosis, diabetic peripheral neuropathy, neurotoxin-induced neurodegeneration, and amyotrophic lateral sclerosis.

Abstract: Embodiments disclosed herein relate to structural, seismic beams and columns as well as to structures including such beams and columns. The seismic beams and columns may be sized, shaped, or otherwise configured to produce approximately even or uniform load distribution (e.g., during a seismic event and/or wind loading event).