Patents by Inventor Paul Wu

Paul Wu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9133433
    Abstract: The present invention relates to a process and apparatus for purifying a molecule of interest from a heterogeneous clarified fluid mixture. The apparatus of the invention generally comprises a continuous perfusion fermentation system, a continuous particle removal system integrated with the perfusion fermentation system; and a continuous purification system integrated with the particle removal system, which is maintained under sterile conditions. The process comprises filtering a heterogeneous clarified fluid mixture by continuous ultrafiltration at a specific flow rate below the transition point of the molecule of interest in the pressure-dependent region of the flux versus TMP curve, wherein the specific flow rate is maintained substantially constant throughout the continuous ultrafiltration.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: September 15, 2015
    Assignee: Bayer HealthCare LLC
    Inventors: Jens Holger Vogel, Roberto Giovannini, Konstantin B. Konstantinov, Huong My Nguyen, Paul Wu
  • Patent number: 9045725
    Abstract: The present invention relates to a process and apparatus for purifying a molecule of interest from a heterogeneous clarified fluid mixture. The apparatus of the invention generally comprises a continuous perfusion fermentation system, a continuous particle removal system integrated with the perfusion fermentation system; and a continuous purification system integrated with the particle removal system, which is maintained under sterile conditions. The process comprises filtering a heterogeneous clarified fluid mixture by continuous ultrafiltration at a specific flow rate below the transition point of the molecule of interest in the pressure-dependent region of the flux versus TMP curve, wherein the specific flow rate is maintained substantially constant throughout the continuous ultrafiltration.
    Type: Grant
    Filed: September 30, 2005
    Date of Patent: June 2, 2015
    Assignee: Bayer Healthcare LLC
    Inventors: Jens Holger Vogel, Roberto Giovannini, Konstantin B. Konstantinov, Huong My Nguyen, Paul Wu
  • Publication number: 20140351800
    Abstract: The present invention relates to an application program establishing platform and a system of performing the same. The application program establishing platform, which is configured to be implementable on a computer to provide a user with a user interface for establishing an application program based on a user-defined logical determining criterion and implementable on a mobile device, includes: a managing module configured to provide the user to set the user-defined logical determining criterion, wherein the user-defined logical determining criterion is based on an if-this-than-that rule, and to compile the application program into a format implementable on the mobile device.
    Type: Application
    Filed: May 21, 2014
    Publication date: November 27, 2014
    Applicant: EVERMORE TECHNOLOGY INC.
    Inventors: Jui-Chi JAO, Ein-Paul WU, Wu-Hsiung HUANG, Feng-Chi YU
  • Patent number: 8536125
    Abstract: The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of ?56° C. or higher.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: September 17, 2013
    Assignee: Bayer Healthcare LLC
    Inventors: Nelly Tsvetkova, Omkar Joshi, Paul Wu, Deqian Wang, Arnaud Desponds
  • Publication number: 20130075891
    Abstract: This invention reveals a flip-chip type full-wave rectification semiconductor device which includes at least a PNNP type and/or NPPN type flip-chip, and a sheet stuff or substrate including a plurality pins, and which is characterized in that: all the soldering points (bumps) of the PNNP type and/or the NPPN type flip-chip are on an identical surface, this can make easy connecting of the pins with the bumps of the flip-chips by soldering in pursuance of circuit arrangement of the full-wave rectification device, and complete manufacturing product after the steps of shaping/packing and cutting; such product has a function of making full-wave rectifying, and can simplify the manufacturing process, reduce the manufacturing cost, and get an effect of reducing the size of the product with better heat dissipation, being different from traditional full wave rectification semiconductor devices composed of two/four grains.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 28, 2013
    Applicant: FORMOSA MICROSEMI CO., Ltd.
    Inventors: Wen-Ping HUANG, Paul Wu
  • Patent number: 8404565
    Abstract: A manufacturing method and a structure of a surface-mounting type diode co-constructed from a silicon wafer and a base plate, in the method, a diffused wafer is stacked with a high temperature durable high strength base plate to have them sintered and molten together for connecting with each other to form a co-constructure; then the diffused wafer is processed by etching and ditching for filling with insulation material, electrodes of the diffused wafer are metalized and all on an identical plane, then production of all functional lines is completed; and then the co-constructure is cut to form a plurality of separated individuals which each forms a surface-mounting type diode to be applied straight. In comparison with the conventional techniques, manufacturing of the present invention is simplified and economic in reducing working hours, size and cost of production and the wafer is not subjected to breaking during manufacturing.
    Type: Grant
    Filed: May 4, 2010
    Date of Patent: March 26, 2013
    Assignee: Formosa Microsemi Co., Ltd.
    Inventors: Wen-Ping Huang, Paul Wu
  • Publication number: 20120211698
    Abstract: The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of ?56° C. or higher.
    Type: Application
    Filed: April 30, 2012
    Publication date: August 23, 2012
    Applicant: Bayer HealthCare LLC
    Inventors: Nelly Tsvetkova, Omkar Joshi, Paul Wu, Deqian Wang, Arnaud Desponds
  • Patent number: 8187799
    Abstract: The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of ?56° C. or higher.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: May 29, 2012
    Assignee: Bayer HealthCare LLC
    Inventors: Nelly Tsvetkova, Omkar Joshi, Paul Wu, Deqian Wang, Arnaud Desponds
  • Publication number: 20110272777
    Abstract: A manufacturing method and a structure of a surface-mounting type diode co-constructed from a silicon wafer and a base plate, in the method, a diffused wafer is stacked with a high temperature durable high strength base plate to have them sintered and molten together for connecting with each other to form a co-constructure; then the diffused wafer is processed by etching and ditching for filling with insulation material, electrodes of the diffused wafer are metalized and all on an identical plane, then production of all functional lines is completed; and then the co-constructure is cut to form a plurality of separated individuals which each forms a surface-mounting type diode to be applied straight. In comparison with the conventional techniques, manufacturing of the present invention is simplified and economic in reducing working hours, size and cost of production and the wafer is not subjected to breaking during manufacturing.
    Type: Application
    Filed: May 4, 2010
    Publication date: November 10, 2011
    Applicant: FORMOSA MICROSEMI CO., Ltd.
    Inventors: Wen-Ping Huang, Paul Wu
  • Publication number: 20110133011
    Abstract: Included are multiend packages of multicomponent yarns, where the yarn is separable into individual ends upon unwinding. The multicomponent yarn may be a bicomponent yarn, such as a yarn including compositionally different polyesters in a side-by-side or eccentric sheath-core configuration. Uses of such multiend packages are also included.
    Type: Application
    Filed: March 19, 2009
    Publication date: June 9, 2011
    Applicant: INVISTA NORTH AMERICA S.A.R.L.
    Inventors: Kah Leap Lee, Young D. Nguyen, Raymond S.P. Leung, Paul Wu
  • Publication number: 20100113744
    Abstract: The invention relates to a method for stabilizing a bulk solution of recombinant protein for frozen storage, which comprises providing a partially-purified solution of recombinant protein which has a monovalent salt concentration of at least 100 mM, and adding a carbohydrate to said solution in an amount sufficient that, upon freezing, the solution has a glass transition temperature of ?56° C. or higher.
    Type: Application
    Filed: April 22, 2008
    Publication date: May 6, 2010
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Nelly Tsvetkova, Omkar Joshi, Paul Wu, Deqian Wang, Amaud Desponds
  • Publication number: 20080269468
    Abstract: The present invention relates to a process and apparatus for purifying a molecule of interest from a heterogeneous clarified fluid mixture. The apparatus of the invention generally comprises a continuous perfusion fermentation system, a continuous particle removal system integrated with the perfusion fermentation system; and a continuous purification system integrated with the particle removal system, which is maintained under sterile conditions. The process comprises filtering a heterogeneous clarified fluid mixture by continuous ultrafiltration at a specific flow rate below the transition point of the molecule of interest in the pressure-dependent region of the flux versus TMP curve, wherein the specific flow rate is maintained substantially constant throughout the continuous ultrafiltration.
    Type: Application
    Filed: September 30, 2005
    Publication date: October 30, 2008
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Jens Holger Vogel, Roberto Giovannini, Konstantin B. Konstantinov, Huong My Nguyen, Paul Wu
  • Publication number: 20080216403
    Abstract: According to the present invention there is provided a stackable and nesting plant-growing container system for a growing medium. The system includes a first growing medium unit and a substantially identical second growing medium unit. The first and second units are each of a unitary construction and includes a sidewall. The sidewall includes an inner side and an outer side, a top edge and a bottom edge. The sidewall includes at least one primary lobe extending from the cross-sectional circumference of the sidewall and uniformly increases in diameter as its distance from the bottom edge of the side wall increases and terminates in the top edge and arranged with an outwardly curving inner side extending outside the growing medium units.
    Type: Application
    Filed: March 7, 2007
    Publication date: September 11, 2008
    Inventors: John Schmidt, Johnson Ling, Paul Wu
  • Publication number: 20070278806
    Abstract: A resilient clip-on handle for mounting on propane bottles includes a unitary resilient sheet including a base member and backing member mounted contiguous to each other so as to be de-formable to a position substantially orthogonally relative to each other. The backing member fits through an opening in a valve protecting collar on a propane bottle. The backing member is sized and shaped so that, when deformed, it may be mounted to lie flush along the underside of a rigid flange extending outwardly from the collar above the opening in the collar. When so deformed, the base and backing members form a common edge therebetween in an interior corner between the base member and backing member. The interior corner snugs against the seam between the flange and the collar. A distal end of the base member, when mounted on the flange, is coextensive with the distal end of the flange.
    Type: Application
    Filed: May 31, 2006
    Publication date: December 6, 2007
    Inventors: Boyd Bechler, Paul Wu
  • Patent number: 7289211
    Abstract: A method of visually quantifying a test material along with an imaging apparatus for practicing the method is disclosed. The method comprises: (a) illuminating the test material at a known angle of incidence with diffuse light of a known and adjustable polarization state; (b) receiving light from the test material with a polarization state modified by the test material; (c) measuring an intensity of the polarization components of the received light for each illuminated pixel substantially simultaneously; (d) calculating the Stokes Vector in two dimensions for each illuminated pixel; and (e) creating an image map for the known polarization state. The method may also include adjusting the known polarization or the incident angle of the diffuse light to create additional image maps. The method and apparatus are intended for use in medical imaging including minimally invasive surgery.
    Type: Grant
    Filed: April 11, 2005
    Date of Patent: October 30, 2007
    Inventors: Joseph T. Walsh, Jr., Paul Wu
  • Patent number: 7102817
    Abstract: An objective lens for a microscope has a casing, a telescopic tube assembly and a cap. The casing is tubular and has a through hole and a window. The telescopic tube assembly has an outer tube, an inner tube and an objective lens. The outer tube is mounted rotatably in the casing and has an inner thread and an annular knob aligned with the window. The inner tube mounted rotatably and moveably in the outer tube. The objective lens is mounted in the inner tube. The cap is mounted on the casing and has two guides mounted between the casing and the cap and slidably engaging the inner tube so the inner tube can move along the guides. The magnification and focal length of the microscope changes when the inner tube with the objective lens moves in the outer tube.
    Type: Grant
    Filed: January 19, 2006
    Date of Patent: September 5, 2006
    Assignee: Anmo Electronics Corporation
    Inventor: Paul Wu
  • Publication number: 20040163248
    Abstract: A thermally enhanced face-up BGA substrate consists of a metal (copper) core, layers, dielectric layers, conductive through-core and build-up vias. It is a new and simple structure with better thermal performance, resulting in lower cost and better reliability. Moreover, high degree of flexibility in choice of material and layer counts as well as layer thickness allows for a wide range of applications in packaging and high density printed circuit board.
    Type: Application
    Filed: February 24, 2004
    Publication date: August 26, 2004
    Applicant: Unicap Electronics Industrial Corporation
    Inventors: Jane Lu, Paul Wu, Ray Chen, Scott Chen, Jeff Chang
  • Publication number: 20040141299
    Abstract: This invention incorporates a new process and structure for manufacturing castellation via in plastic chip carrier. It allows the creation of uniform side wall contacts in the shape of half-cylinders, devoid of any burrs and power dust particles, which when present in a plastic chip carrier, would prevent reliable electrical contacts by causing either short or open circuits. Thus the invention enables plastic chip carrier as a practical way of replacing traditional ceramic chip carriers.
    Type: Application
    Filed: January 9, 2004
    Publication date: July 22, 2004
    Applicant: Unicap Electronics Industrial Corporation
    Inventors: Edward Huang, Jonny Ma, Scott Chen, Paul Wu
  • Patent number: 6711812
    Abstract: A method of making a thermally enhanced BGA substrate in which a metal (copper) core, has dielectric layers applied to each side thereof and conductive through-core build-up vias are provided. Rigidifying non-conductive dielectric sheets are laminated to the oppositely facing surfaces and then conductive layers are applied to at least one of the rigidifying non-conductive sheets and via connections are made through the dielectric layer(s) to the core conductive layer.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: March 30, 2004
    Assignee: Unicap Electronics Industrial Corporation
    Inventors: Jane Lu, Paul Wu, Ray Chen, Scott Chen, Jeff Chang
  • Patent number: 6675472
    Abstract: A process for forming a burrless castellation for a plastic chip carrier comprising forming one or more through holes in a substrate, plating the through holes with a metal to a thickness ranging from about 2 microns to about 6 microns, routing slots along the line extending through the through holes to produce half cylinder-shaped side-contact surfaces, and plating the half cylinder-shaped side-contact surfaces to a thickness in the range of 15 to 25 microns.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: January 13, 2004
    Assignee: Unicap Electronics Industrial Corporation
    Inventors: Edward Huang, Jonny Ma, Scott Chen, Paul Wu