Abstract: Implant preparations capable of sustained action when inserted are comprised of powder of a natural lipoidal substance in thorough admixture with bioactive macromolecule, followed by compression under pressure into a disc or rod that can be broken and used in small pieces as well.

Abstract: An implant comprises interconnected compartments with intlet and outlet and can be used for sampling of entered serous fluid or to hold drug concentrate for selective delivery, if desired. The compartments are formed by sealing around porous foam rings between a top and a bottom layer of biocompatible elastic membrane with a polymer paste which sets to form a rubbery shell. The top membrane layer over the compartment is punctured to create a small resealable channel. Upon subcutaneous implantation, serous fluid under hydrostatic pressure seeps into the interior through the puncture orifice. The entered fluid may be withdrawn by an hypodermic syringe through the rubbery side wall to obtain serum-borne bioactive materials. If a drug concentrate is included, the entered fluid will dissolve some of the drug therein. When delivery is required, external sidewise compression of the elastic compartment over the skin fold expels the drug containing solution therein through the orifice.

Abstract: A compression device, which enables standard-size flexible solution containers to infuse at a constant flow rate, comprises a rigid external casing, in combination with two leak-proof sacs inflatable by a low pressure gas, and a flow moderator system. The flexible solution container must be positioned evenly in-between the inflatable sacs in order to obtain constant delivery rate while discharging about 80% of its intended maximum content. Flow moderators connected in series with by-passes can provide flow rates in discrete steps. The disposable compression device is adaptable to drug infusion and fluid replenishment therapy.

Abstract: The method of making skin covering materials especially for wounds comprising dextran C insolubilized by reaction with epichlorohydrin in combination with a suitable humectant. The compositions may be formed into coherent, self-supporting sheets of the insolubilized dextran C impregnated with humectant material, or in the form of pastes applied to the wound as such. The humectant material is preferably glycerin or isopropanolpropylene glycol and an oil. The wound covering material allows sufficient removal of exuded body fluid and seals the wound site against bacterial infection, while at the same time maintaining the wound moist to prevent scale formation. The method may include incorporating medicaments into the wound covering material, to assist in healing and further to safeguard against bacterial infection.

Abstract: Skin covering materials especially for wounds comprise dextran C insolubilized by reaction with epichlorohydrin in combination with a suitable humectant. The compositions may be in the form of coherent, self-supporting sheets of the insolubilized dextran C impregnated with humectant material, or in the form of pastes applied to the wound as such. The humectant material is preferably glycerin or isopropanolpropylene glycol and an oil. The wound covering material allows sufficient removal of exuded body fluid and seals the wound site against bacterial infection, whilst at the same time maintaining the wound moist to prevent scale formation. Medicaments may additionally be incorporated into the wound covering material, to assist in healing and further to safeguard against bacterial infection.